Is Xantho Healthy?

[Singleton]

I know you hate studies, but these call the active constituent in Xantho, epipolythiodioxopiperazine, a toxin.

ETP toxins have been shown to inhibit a variety of enzymes via interaction with sensitive cysteine residues.

The toxin lowers ATP in intact cells and inhibits the rate of ATP synthesis in permeabilzed cells. Comparison with the effects of the known ATP synthase inhibitor oligomycin B is consistent with ATP synthase as an early target in scabrosin ester-induced cell death.

http://www.ncbi.nlm.nih.gov/entrez/...ve&db=pubmed&dopt=Abstract&list_uids=12902194


Influx of calcium through a redox-sensitive plasma membrane channel in thymocytes causes early necrotic cell death induced by the epipolythiodioxopiperazine toxins.
http://www.ncbi.nlm.nih.gov/entrez/...ve&db=pubmed&dopt=Abstract&list_uids=12063251


Gliotoxin induces apoptosis in macrophages unrelated to its antiphagocytic properties.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=2461370

Is attacking macrophages a good thing? Nelson, what's all this about?

There are more. Just search epipolythiodioxopiperaziabrogatedne

 

[ProtienFiend]

yipes...!! thats a long name!

 

[Nelson Montana]

No need for concern bro. For one thing, xantho has been tested and approved and found to be very safe. Did you know that yohimbe is considered a toxin, and in some cases an actual poison? Lots of things will cause macrophage damage, including exercise. DNA damage happens every time you take a breath. All these studies were done at the same place in Australia in vitro -- which about 20 steps before even animal studies. It's all abstracts with no real life applications. In other words, I wouldnt worry about it.

 

[Singleton]

Thanks for the answer.