Please Scroll Down to See Forums Below
Is Ephedrine Anti-catabolic???
- Thread starter AlPhASiLvErBaCk
- Start date
JP@Ironology
New member
Nelson Montana said:
I would say ephedrine is NOT one of the worst supplements available. Potentially dangerous yes, worthless hell no. I have never had a problem with ephedrine. I especially like it with caffeine.
There is not a wealth of data on ephedrine and nitrogen retention, but this study does suggest an anabolic effect.
Clin Sci (Lond) 1992 Jan;82(1):85-92
Effects of chronic administration of ephedrine during very-low-calorie diets on energy expenditure, protein metabolism and hormone levels in obese subjects.
Pasquali R, Casimirri F, Melchionda N, Grossi G, Bortoluzzi L, Morselli Labate AM, Stefanini C, Raitano A.
Istituto di Clinica Medica 1, Ospedale S. Orsola, University Alma Mater of Bologna, Italy.
1. We investigated the effects of the chronic administration of a sympathomimetic agent on energy expenditure, protein metabolism and levels of thyroid hormones and catecholamines in 10 obese subjects after a 6-week very-low-calorie-diet programme (1965 kJ, 60 g of protein, 45 g of carbohydrates). L-(-)-Ephedrine hydrochloride (50 mg three times a day by mouth) or placebo were administered during 2-week periods (weeks 2-5 of the VLCD programme) in a randomized, double-blind, cross-over design. Five subjects began with ephedrine and five with placebo. 2. The results were analysed separately in the two groups. No difference was found between them as regards weight loss during the very-low-calorie diet and drug treatments. Conversely, ephedrine therapy induced a significantly lower daily urinary excretion of nitrogen (and, consequently, a better nitrogen balance) with respect to placebo, independently of the drug sequence. Daily urinary levels of 3-methylhistidine during ephedrine and placebo treatments were similar. The fasting resting metabolic rate (oxygen consumption, ml STP/min) fell significantly during the very-low-calorie diet in both groups, but this effect was partially and significantly prevented by administration of ephedrine. Diet therapy significantly reduced 24 h urine levels of vanillylmandelic acid and homovanillic acid, which, however, increased to pretreatment values during ephedrine treatment. No significant effects were shown on 24 h urinary concentrations of adrenaline, noradrenaline and dopamine during the very-low-calorie diet and/or ephedrine treatment.
www.cuttingedgemuscle.com
JP@Ironology
New member
nandi12,
Excellent post bro.
Excellent post bro.
Good point gimp.
macdbo: Please do not buy my book. You may be forced to learn something and you'll hurt your head.
Let's take a look at the last study nandi posted. (Thanks bro). It essentially showed no fat loss between the two groups. The only difference was less nitrogen excretion, which does NOT suggest anabolism. There can be several reasons for this, among which is prostate enlargement and thus, lessened urinary flow. (Epehedra can cause BPH).
The first study shows an elevation of thermogenisis (albiet slight) and a quick return to homeostatsis. That's the problem with all CNS. They jack you up, then the body adapts and the effects plateau.
That's not so bad in itself, but there's more.
Once you go off, the metablism is more sluggish than before, leading to...you guessed it, hoarding fat. In order to maintain a thermogenic state, you'd have to use so much, you'll feel like you're on DNP.
Ephedrine is a quick fix that, in the long run, works against your goals. But again, people think it works, because it does -- for a while. Can anyone seriously say they kept the fat off from a cycle of ephedrine? Chances are, it just gets harder and harder.
Ephedrine would be good for someone who needed a boost of energy for a specific activity. But long term use makes it a terrible choice for bodybuilders looking to build muscle and burn fat.
You know what's a proven anti-catabolic? Carbs.
macdbo: Please do not buy my book. You may be forced to learn something and you'll hurt your head.
Let's take a look at the last study nandi posted. (Thanks bro). It essentially showed no fat loss between the two groups. The only difference was less nitrogen excretion, which does NOT suggest anabolism. There can be several reasons for this, among which is prostate enlargement and thus, lessened urinary flow. (Epehedra can cause BPH).
The first study shows an elevation of thermogenisis (albiet slight) and a quick return to homeostatsis. That's the problem with all CNS. They jack you up, then the body adapts and the effects plateau.
That's not so bad in itself, but there's more.
Once you go off, the metablism is more sluggish than before, leading to...you guessed it, hoarding fat. In order to maintain a thermogenic state, you'd have to use so much, you'll feel like you're on DNP.
Ephedrine is a quick fix that, in the long run, works against your goals. But again, people think it works, because it does -- for a while. Can anyone seriously say they kept the fat off from a cycle of ephedrine? Chances are, it just gets harder and harder.
Ephedrine would be good for someone who needed a boost of energy for a specific activity. But long term use makes it a terrible choice for bodybuilders looking to build muscle and burn fat.
You know what's a proven anti-catabolic? Carbs.
