i never shoot in the quads because of the pain, but in the past when i did shoot i nthe quads i would fill the syringe the poor really warm water over the syringe to warm the oil to make it easier to inject and also help it to spread out. then after injectiuon take a warm wash coth and just run the area a for a little while this will break down some of the oil and spread it out as well and this will also keep some swelling down which will keep away alot of pain.