igf-1 questions...need some help

[browndog1]

I have a friend who is looking into IGF-1, so I'm helping him out on this. There's a few questions that I have read conflicting views/answers on, so I'm hoping to get a general concensus from the experienced and well-read members here.

When I mention "igf-1" anytime below, I'm referring to "Long R3 IGF-1."

- What is the deal with igf-1 gyno? What is the cause (estro, progest, prolactin)?? What drug, if any, can prevent that side effect from occuring? (femara, aromasin, anas, nolva?)

- What is the deal with doing fina while on igf-1? Fina naturally increases igf-1 levels, and that's one reason why it is awesome. But if someone took 30mcg/day of igf-1 with fina, would that be a contributor to igf related gyno?

- In taking igf at the above stated dosage (for 30 days), would test (and fina?) be a good choice to go with the igf-1? Test only? Oral compounds too? I've read that results on a single 30 day plan (30 days for reasons of downregulation and dimishing results) while in the midst of some test or orals is amazing.

- I've read that low dose gh (approx 2iu/day) is great with igf-1, since "GH alone causes a downregulation of the natural production of insulin-like growth factors, and IGF alone inhibits natural production of GH." (quotes = Ironmaster) What are your thoughts on this?

- After receiving igf-1 (shipped in BA), what are the proper storage procedures? Is the accepted method of administration to use a u100 slin dart, take your 30mcg out (3iu), fill the rest of the way with Bacteriostatic water, then inject?

- I've read that injecting IM causes site growth in lagging areas, however most studies that have been posted deal with IV administration. Is the IM site growth statement above incorrect? If not, is SubQ the way to go? Any reason to use it for localized fat loss (like gh)?


Any other opinions on dosage, ancillaries, and results appreciated.


...bd

 

[browndog1]

bump..

...bd

 

[browndog1]

I was speaking with a well-respected member of this board through email about these questions, and wanted to share his responses with everyone.


- What is the deal with igf-1 gyno? What is the cause (estro, progest, prolactin)?? What drug, if any, can prevent that side effect from occuring? (femara, aromasin, anas, nolva?)

IGF-1 gyno would be caused by the IGF-1 itself.
Remember that IGF-1 is responsible for cell
differentation and proliferation so the chance of gyno
is real, but likely not very common.


- What is the deal with doing fina while on igf-1? Fina naturally increases igf-1 levels, and that's one reason why it is awesome. But if someone took 30mcg/day of igf-1 with fina, would that be a contributor to igf related gyno?

It certainly could be but as stated above I think
having increased IGF-1 alone is likely not going to be
the biggest factor in causing gyno. I firmly beleive
you need a host of increased hormones to really get
gyno so if you dont try and overdue it with test etc
while using IGF-1 and/or tren then it likely wont be a
big deal.

- In taking igf at the above stated dosage (for 30 days), would test (and fina?) be a good choice to go with the igf-1? Test only? Oral compounds too? I've read that results on a single 30 day plan (30 days for reasons of downregulation and dimishing results) while in the midst of some test or orals is amazing.

Many orals work in the liver to increase natural IGF-1
production and likely why test/orals/igf-1 are such a
powerfull combo.

- I've read that low dose gh (approx 2iu/day) is great with igf-1, since "GH alone causes a downregulation of the natural production of insulin-like growth factors, and IGF alone inhibits natural production of GH." (quotes = Ironmaster) What are your thoughts on this?

There really is not a lot of good solid research on
this that I have found to directly correlate its use
in bodybuilding so a lot of this is speculation based
on what info we do have.

- After receiving igf-1 (shipped in BA), what are the proper storage procedures? Is the accepted method of administration to use a u100 slin dart, take your 30mcg out (3iu), fill the rest of the way with Bacteriostatic water, then inject?

BA works as a very powerfull solvent on many plastics
etc so I would not leave in syringe for any lentgh of
time. The BA can also likely cause localized soreness
at injection site. I have not igf-1 myself but you may
want to try and dilute it a bit with sterile water and
if you day it will likey make it viable for a couple
weeks. Once again just speculation based on the facts
I have about GH, but igf-1 is similar.

I've read that injecting IM causes site growth in lagging areas, however most studies that have been posted deal with IV administration. Is the IM site growth statement above incorrect? If not, is SubQ the way to go? Any reason to use it for localized fat loss (like gh)?

I would not expect as much localized fat loss from
IGF-1 as from GH, they work together but are similar
in some aspects. The fact that igf-1 is responsible
for cell differentation and proloferation I can see
where one could draw the conclusion that IM could
cause localized mass increasses but once again a lot
of this is speculation and has nothing to back it up.
Now that its bocoming more readily available we
should be hearing a lot more good info about it.


another question I added...
- I've read that 1mcg of igf-1 = 1.5iu of gh. This basically says that igf blows gh away, and best of all, you only use for a month at a time. Do you agree?

I dont think its a safe or realistic to compare the 2
in that manner. Fo mass gains I would likely agree,
GH is not an anabolic hormone, its a diabetogenic
hormones and anabolic properties displayed from its
use are largely due to the effects it has on the rest
of the hormonal system and not because it directly
causes them.



Hope this helps some of you out.


...bd

 

[ripper2]

i've been taking 30mcg IGF for the past week and have found the best way to measure it out is to take a U100 slin dart (if you can get the tuberculin pins they are better b/c supposedly the IGF needs to be drawn with a larger pin. i use a 20g and then swtich back to a 27g slin pin to shoot)

first draw in 50-70 units of bacteriostatic water. then draw 3 units of IGF, then draw in some more Bacteriostatic water to wash the IGF out of the pin. if u dont' add the water first its REAL hard to correctly measure out 3units of IGF b/c basically the pin itself holds that much, so to get the air out of the syringe and CORRECTLY measure out 3iu the only way to do it is to draw in some water first.

it should store fine in the BA. i would still try to keep it at room temp and out of sunlight and to handle it as carefully as possible though

 

[browndog1]

Thanks for the idea ripper. Definitely a good one.

So it's been a week, have you noticed anything yet? (besisdes the hunger I've heard about?)

thanks.

...bd

 

[ripper2]

i don't know if its placebo effect or not, but since i started taking the IGF i seem to have more definition all over.
i've basically changed my diet to eating ~350g protein/day and then whatever else i want. its almost like i eat on a bulker... BUT i still seem to be leaning out. im DEFINITELY much much fuller than i was while dieting, but that is probably just do to the increased food intake. have set a few new PRs in the weight room which could be due to the IGF or could just be the cycle and that im now eating more i've got more strength in the wieght room.

i'd really like to do 50mcg/day for a month and see what happens.