How does Aromasin work exactly?

[Zyglamail]

when you stop aromasin, you have to essentially wait for the body to produce more aromatase enzyme which is a slow process. my only confusion, is that if the body senses deactivated aromatase enzyme, would it create more, as a reaction to taking aromasin? and you would become tolerant to it?

According to the initial phase one trial...

Maximal suppression of serum estrogen concentration (22-37% suppression) was achieved 3-4 days after single-dose administration of exemestane (25 mg or 50 mg), and almost no suppression was observed 2 weeks later. A significant decrease in the amount of urinary estrogen excretion occurred on day 4 and day 8 after exemestane administration. The level of urinary estrogen excretion almost returned to baseline levels in the 25 mg group and returned to 65% of baseline levels in the 50 mg group 2 weeks after drug administration.

Many cells in the body produce estrogen AND the aromatase enzyme is located in the endoplasmic reticulum of the cell so I dont believe there is a feedback mechanism for it like there is systemically needed hormones.