I can see it being worth it if ..
1. you are tight for cash,
2. you stay on for long periods of time, and at high dosages
3. you are the "crafty" kinda person who enjoys doing things like that to save a buck.
For me, the only powders I can justify buying is Var powder, just because its is SIGNIFICANTLY cheaper than buying human grade stuff. I would be broke running var how I wanted at the dosage I wanted as human grade. Also, I dont need to worry about cooking and sterility issues as I am taking it orally.
I dont run tren (which I agree is pricy), and I get my gear already for pretty cheap. The more sources you get to know over time, the better deals you can find. I like to buy human grade gear. No fucking around, I get it, open it, and shoot it. I dont have to brew shit, or worry about messing anything up. I know a few folks who have invested in a LOT of var powder, and tried to brew it, and it crashed on them. Waste of var!
But .. if I wanted to invest the time and effort into brewing it, i would. For instance, I am the type of person that if something goes wrong with my car, other than brakes and oil changes, tires etc, I am taking it in. My life is pressed for time huge as it is. I struggle to get workouts in, so I dont have the time, to take a Saterday afternoon and try to work on it for example. I would rather take it in to someone, pay, and have them do it for me. Catch my drift?
My cycles are shorter now, (6ish weeks), and I dont run expensive gear choices, with the excpetion of var, which will be powder brewed, by a good friend of mine!

A few bottles of prop or NPP or EQ are not expensive nowadays. Prices are getting very competetive. Christ omnadrens are going for "candy bar" price these days per amp. Its getting more and more competetive.
Mavy