None of this information is correct. It is all a rehash of a post many years ago by a guy with the handle of Dr. Swale. He made it all up. It's total BS.
Swale said to use 250 iu to prevent primary hypogonadism from desensitization of the leydig cells. Desensitization doesn't exist. When the leydig cells stop producing testosterone it's because they have used up the available cholestrol. The leydig cells use cholesterol to make testosterone.
Here is an article from pubmed:
Evaluation of endocrine testing of Leydig cell function using extractive and recombinant human chorionic gonadotropin and different doses of recombinant human LH in normal men.
Cailleux-Bounacer A, Reznik Y, Cauliez B, Menard JF, Duparc C, Kuhn JM.
Department of Endocrinology and INSERM CIC 204, Rouen University Hospital, 76000 Rouen, France.
BACKGROUND: The functional testing of endocrine testis uses extractive human chorionic gonadotropin (ehCG). Recombinant human hCG (rhCG), avoiding any contamination, should replace ehCG. Moreover, a functional evaluation with recombinant human LH (rhLH) would be closer to physiology than a pharmacological testing with hCG. METHODS: The study was conducted in normal men. We first evaluated the dose-effect of ehCG on plasma testosterone and estradiol levels, before and after injection of either hCG or vehicle. Secondly, the responses to the optimal dose of ehCG were compared with those of rhCG. Thirdly, we investigated the dose-effect of rhLH, on steroid hormone secretion. LH, testosterone, and estradiol plasma levels were measured after the injection of either rhLH or placebo. RESULTS: ehCG induced dose-dependent increases in plasma estradiol and testosterone levels. They respectively peaked at 24 and 72 h after the injection. The most potent dose of ehCG (5000 IU) induced results similar to those observed with 250 microg (6500 IU) rhCG. By comparison with placebo, rhLH induced a significant and dose-dependent increase in plasma testosterone levels 4 h after the injection. Peak response of testosterone to rhLH and rhCG was significantly correlated. rhLH did not induce significant change in plasma estradiol level. CONCLUSIONS: In normal men, a single i.v. injection of 150 IU rhLH induces a 25% rise in plasma testosterone levels by comparison with placebo. At the moment, the dynamic evaluation using hCG remains the gold standard test to explore the Leydig cell function. The use of 250 microg rhCG avoiding any contamination should be recommended.
PMID: 18495695 [PubMed - indexed for MEDLINE]
Please take note of this "250 microg (6500 IU) rhCG" so 250 microg is equal to 6500 iu" And to this "The use of 250 microg rhCG avoiding any contamination should be recommended."
So the doctors that did this study on normal men said to use 6500 IU as a recommended dose ofrhCG, and there is no doubt that what you have is rhCG. If you are shut dow, a single injection of 200mg of testosterone enantahte will shut you down, the standard dosage to use is 6500 iu. 250 iu twice a week won't do shit!!!
Don't take my word for it take the word of the people that did the study. And not some quake that made it all up so he could boost the numbers of his clinic.
And just to avoid confusion lets look at this line: a single i.v. injection of 150 IU rhLH induces a 25% rise in plasma testosterone levels by comparison with placebo" This is not hCG this is hLH. So you can't compare the two.