I've not been great at a few things at first...But it never takes me long to at least get to the point of being decent at something. I'm athletic and I learn fast.
That said, there's probably some things I never tried and probably never will that would pwn me. I don't really see myself ever being good at lacrosse for some reason. I live with two former college lacrosse players and I haven't once tried to get them to teach me, either lol. We've even got lacrosse nets set up in the backyard and I haven't gone near it haha.