Well, my natural FSH and LH are 2 and 3 times the maximum range and yet I make no test at all according to my doc. I would think if you shut down your natural production of anything that eventually your body will not make it at all which would be no different than your body becoming resistant to a drug that makes it produce something. As for eating sugar, your body doesn't get overworked and develop type II diabetes. I never ate sugar, watched what I ate and I am not fat by any means. Last year my sugar levels were fine, this year they are elevated. I am not type II, but run the risk of becoming type II. It is a heriditary thing to some extent as my grandfather had type II. I would think if we could keep all our homorn levels balanced at the levels they were say when we were 25, then we wouldn't have a problem, but something in our genes tells our bodies to start doing things different when we reach a certain age.