Good Test Levels but Low LH./High Estradiol

[ColtSSBR]

On TRT (Test Cyp, HCG, Anastrozole) for low test etc.

Most recent bloodwork shows greatly improved test levels(1500) but now my LH is very low and frikin estradiol back up to 51.

One suggestion was to drop the Anastrozole and switch to Tamoxifen for awhile.

Anyone else have this problem before? What worked for you?

Dosages:
Test Cyp 100mg twice a week.
HCG 250 IU twice a week.
Anastrozole .5 EOD

Thanks

 

[Zyglamail]

Your E is high because your T is high. Your E will go through the roof if you drop ana and start nolva. You do realize that nolva does NOT prevent the creation of E dont you? It simply competes with E at the receptor.

I would simply up the ana to 1 EOD.

Since your on TRT, what does the doc say?

As for low LH, LH triggers test production, you dont need any produced so why would you expect it to be anything but low?

 

[caribeman]

Zyg is right. First of all talk to your doc about this but you can mention to up your Anas to 1mg per day.

 

[ColtSSBR]

Your E is high because your T is high. Your E will go through the roof if you drop ana and start nolva. You do realize that nolva does NOT prevent the creation of E dont you? It simply competes with E at the receptor.

I would simply up the ana to 1 EOD.

Since your on TRT, what does the doc say?

As for low LH, LH triggers test production, you dont need any produced so why would you expect it to be anything but low?

I wish to stay with the Anastrozole and it made sense to me to simply increase the dosage.

The main reason I posted this is because I was told (Dr) that the Tamoxifen can raise the LH and reduce the E, while the Anastrozole simply reduces/blocks the E. As I look around, I don't really see where this is an accurate statement as far as raising the LH.

 

[Zyglamail]

I wish to stay with the Anastrozole and it made sense to me to simply increase the dosage.

The main reason I posted this is because I was told (Dr) that the Tamoxifen can raise the LH and reduce the E, while the Anastrozole simply reduces/blocks the E. As I look around, I don't really see where this is an accurate statement as far as raising the LH.

The body has multiple feedback mechanisms to try and keep hormone levels in check. In men the majority of E comes from aromatising T.

So, if T is high, natural E will be high as there is more T to aromatise.

In someone not taking exo T, if you take nolva it will block many of the bodies E receptors so that E can not occupy them, This artifically makes the body think that T is low since E is a result of aromatizing T. To trigger more T production LH output is increased. However the body also monitors T levels so as LH increases and in turn T increases, if Nolva is still in use and blocking the E receptor there will come a point when the elevated T levels alone with tell the body there is already high enough T even if it cant seem to register high enough E (because nolva is blocking the receptors).

Now, in your case, your T is already high, my bet would be high enough that you wont be able to fool your body into producing more LH even if E receptors are blocked so body thinks E is low.

IS your doc an endo or what kind of experience does he have? low LH is the norm in your situation and I dont think you are going to be able to increase it much, and if you did to what end? Your E levels seem in line with your T levels and I am assuming you dont mind high T but would like to lower E a bit, hence my initial suggestion.

 

[ColtSSBR]

The body has multiple feedback mechanisms to try and keep hormone levels in check. In men the majority of E comes from aromatising T.

So, if T is high, natural E will be high as there is more T to aromatise.

In someone not taking exo T, if you take nolva it will block many of the bodies E receptors so that E can not occupy them, This artifically makes the body think that T is low since E is a result of aromatizing T. To trigger more T production LH output is increased. However the body also monitors T levels so as LH increases and in turn T increases, if Nolva is still in use and blocking the E receptor there will come a point when the elevated T levels alone with tell the body there is already high enough T even if it cant seem to register high enough E (because nolva is blocking the receptors).

Now, in your case, your T is already high, my bet would be high enough that you wont be able to fool your body into producing more LH even if E receptors are blocked so body thinks E is low.

IS your doc an endo or what kind of experience does he have? low LH is the norm in your situation and I dont think you are going to be able to increase it much, and if you did to what end? Your E levels seem in line with your T levels and I am assuming you dont mind high T but would like to lower E a bit, hence my initial suggestion.

I see and was not aware that the low LH is commonplace in these situations- I'm fairly new to this. Actually, I'm using a TRT specialist who has been extremely helpful. However, I'm not sure why the Tamoxifen suggestion???
I am going to up the Anastrozole and see where I'm at in a few weeks.
Thank you,

 

[straitedge52]

Consider HCGenerate along with Forma Stanzol. So far for the lat 10~12 weeks this combo has been spot on for me.

 

[Zyglamail]

I see and was not aware that the low LH is commonplace in these situations- I'm fairly new to this. Actually, I'm using a TRT specialist who has been extremely helpful. However, I'm not sure why the Tamoxifen suggestion???
I am going to up the Anastrozole and see where I'm at in a few weeks.
Thank you,

as I said, LH causes test production, your test is already high so it makes sense the body would reduce production of the signaling chemical responsible....

Luteinizing Hormone

In both sexes, LH stimulates secretion of sex steroids from the gonads. In the testes, LH binds to receptors on Leydig cells, stimulating synthesis and secretion of testosterone. Theca cells in the ovary respond to LH stimulation by secretion of testosterone, which is converted into estrogen by adjacent granulosa cells.

 

[hayjay7]

This is an interesting conversation for me.

I'm currently in the process of possibly switching my protocol to a clinic and had blood work done recently.

My test results came back with high E (52) and low LH. The clinic suggested tomaxifin as well, citing the low LH.

Their suggested dosage of test was pretty large also.

 

[pendit]

Consider HCGenerate along with Forma Stanzol. So far for the lat 10~12 weeks this combo has been spot on for me.

How much HCGenerate are you taking? How many pumps of Forma? How many times a day?