Vandyl Sulfate does not work at all. There is an article in this months Muscular Develpoment about Supps that work, supps that are in there early stages, and supps that should be thrown away. Guess were Vandyl Sulfate came in! Cretaine is said to work, but you will loss anywhere between 30-50% of your gains in a matter of a couple of weeks. Creatine is good to use after you do a cycle and thats about it.