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Glutamine: Why It's Important

beefybull

Banned
I originally posted this on the Anabolic board, but figured it'd be good to post here also.

What is Glutamine?
Glutamine is considered a "conditionally essential amino acid". It makes up roughly 61% of the amino acid pool in skeletal muscle.

What does Glutamine do?
- It is an acid/base balancer
- It is a nitrogen carrier
- It is a precursor to macromolecules (proteins & nucleic acids)
- Glutamine (not carbs or fat) is the preferred source of fuel for rapidly dividing cells, such as enterocytes (intestinal cells) and lymphocytes (immune system cells).
- It is a cell volumizer
- It aids in recovery
- It performs other functions as well

How much should I take & when?
Although glutamine is a popular supplement, this question pops up quite often. The amount of glutamine you should take depends on your bodyweight. Dosages at .57g/kg bodyweight have been shown to be safe in short term use. The body needs a minimum of .2g/kg to have a positive effect on nitrogen balance. Here is a chart of daily dosages by body weight (at .2g/kg):
140lbs - 12.7g
150lbs - 13.6g
160lbs - 14.5g
170lbs - 15.4g
180lbs - 16.3g
190lbs - 17.2g
200lbs - 18.1g
210lbs - 19.1g
220lbs - 20g
230lbs - 20.9g
240lbs - 21.9g
250lbs - 22.7g
260lbs - 23.6g
270lbs - 24.5g

Although you could probably take your full daily dosage at once, it may not be the most comfortable thing to do so. Glutamine should not be taken with food, as it will drastically decrease the amount of glutamine that is absorbed. It is best taken post-workout with carbs & protein, or before bed, since Glutamine is believed to cause an increase in growth hormone (and this is an ideal time for this). As Huckleberry Finnaplex suggested, you could also take it in the morning on an empty stomach.

Glutamine is easily one of the top 5 OTC supplements that a bodybuilder should use. In fact, it could be #1 or maybe a close #2 (behind Creatine). It is currently more expensive than creatine, but the price has drastically dropped over the past 18 months. Hope this helps!

BeefyBull
 
Glutamine promises a lot of benefits, it is the uptake that seems to be of the greatest concern... There seems to be a lot of conflicting evidence on bio-availability as well as "best time" to take..
 
Glutamine is questionable at this time. Dosages taken in studies are high and costly. I've never been impressed, I just take my protein like a good boy and don't worry about additional glutamine anymore.
 
asdf

glutamine for me has helped huge. In high dosages though. at 195lbs with abs under good lighting I was taking about 40 g´s a day, and making amazing gains.
try
10gs in the morning
10gs pre workout
10gs postworkout
10gs before bed

or whatever dosage fits your body weight, but those times seem to be the most effective
 
The jury is still out on glutamine. Like Macro said, it's the uptake that is of concern.

Former studies were based upon intravenous dosages; glutamine's effectiveness via the alimentary tract has not yet been fully established.

That being said, there is anecdotal evidence, just no controlled studies.

There may be promise in glutamine peptides, but that has not yet been established, either.
 
MikeMartial said:
The jury is still out on glutamine. Like Macro said, it's the uptake that is of concern.

Former studies were based upon intravenous dosages; glutamine's effectiveness via the alimentary tract has not yet been fully established.

That being said, there is anecdotal evidence, just no controlled studies.

There may be promise in glutamine peptides, but that has not yet been established, either.
Has there been any progress on this in the last 2 years?
 
Thank you, I stopped taking Glutamine several years ago I forgot how essential it is but I will be back on!
beefybull said:
I originally posted this on the Anabolic board, but figured it'd be good to post here also.

What is Glutamine?
Glutamine is considered a "conditionally essential amino acid". It makes up roughly 61% of the amino acid pool in skeletal muscle.

What does Glutamine do?
- It is an acid/base balancer
- It is a nitrogen carrier
- It is a precursor to macromolecules (proteins & nucleic acids)
- Glutamine (not carbs or fat) is the preferred source of fuel for rapidly dividing cells, such as enterocytes (intestinal cells) and lymphocytes (immune system cells).
- It is a cell volumizer
- It aids in recovery
- It performs other functions as well

How much should I take & when?
Although glutamine is a popular supplement, this question pops up quite often. The amount of glutamine you should take depends on your bodyweight. Dosages at .57g/kg bodyweight have been shown to be safe in short term use. The body needs a minimum of .2g/kg to have a positive effect on nitrogen balance. Here is a chart of daily dosages by body weight (at .2g/kg):
140lbs - 12.7g
150lbs - 13.6g
160lbs - 14.5g
170lbs - 15.4g
180lbs - 16.3g
190lbs - 17.2g
200lbs - 18.1g
210lbs - 19.1g
220lbs - 20g
230lbs - 20.9g
240lbs - 21.9g
250lbs - 22.7g
260lbs - 23.6g
270lbs - 24.5g

Although you could probably take your full daily dosage at once, it may not be the most comfortable thing to do so. Glutamine should not be taken with food, as it will drastically decrease the amount of glutamine that is absorbed. It is best taken post-workout with carbs & protein, or before bed, since Glutamine is believed to cause an increase in growth hormone (and this is an ideal time for this). As Huckleberry Finnaplex suggested, you could also take it in the morning on an empty stomach.

Glutamine is easily one of the top 5 OTC supplements that a bodybuilder should use. In fact, it could be #1 or maybe a close #2 (behind Creatine). It is currently more expensive than creatine, but the price has drastically dropped over the past 18 months. Hope this helps!

BeefyBull
 
Wow..and to think I neglected glutamine and creatine for so long. Do you have to ween(spelling) yourself off of this supp or creatine or protien shakes? I do about 1-2 shakes per day and try consuming most of mine from foods. But as for creatine and glutamine can they stay as the basic supps in your regimen? Also kind of a dumb question but on days ur not working out I assume I am correct in still taking it?
 
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