Fro. Prolactin, PR, Fina. Help with answers

[Hugh Gellatts]

if it is worth anything, i do hold a little water on tren/vitex but hold none on tren alone (could be increased progesterone causing this). the addition of winstrol completely negates this though.

 

[nandi12]

While it is true that prolactin can suppress gonadotropin levels, and low levels of testosterone (T), luteinizing hormone (LH) and follicle stimulating hormone (FSH) often accompany hyperprolactemia, this is not always the case, suggesting that prolactin can lead directly to gynecomastia/galactorrhea without an effect on gonadotropin secretion. (1) (2) (3)

On the other hand there have been negative studies in which patients with elevated drug-induced prolactin but with normal gonadotropin levels did not present with gynecomastia.(4)

It would be interesting to know how many bodybuilders who take testosterone and tren, along with arimidex or nolvadex, develop gyno. If gyno occurs in these subjects it would suggest a direct action of prolactin rather than an indirect action via a depressed testosterone/estrogen ratio. Any readers out there with experience in this regard?

(1)Nephron 1986;42(1):19-22
Parlodel treatment of uremic hypogonadism in men.
Ermolenko VM, Kukhtevich AV, Dedov II, Bunatian AF, Melnichenko GA, Gitel EP.

(2)J Clin Pharm Ther 2002 Feb;27(1):75-7
Gynecomastia with sulpiride.
Kaneda Y, Fujii A.

(3) Schweiz Arch Tierheilkd 1996;138(5):241-4
[Gynecomastia in a goat buck]
Janett F, Stockli A, Thun R, Nett P.

(4) Ann Pharmacother 2001 Dec;35(12):1523-7
Effects of risperidone on gonadal axis hormones in schizophrenia.
Kaneda Y.

 

[jatos]

This makes alot of sense and I compliment the amount of work that has gone into this thread.

I have a question though, How much of an effect would taking T3 along with Tren have on prolactin?

Fonz, you have cleared up the relation between TRH and Prolactin levels. So would continuing Tren after finishing a T3 bout be a NO NO? What do you think?

 

[perfectspecimen]

would it be wise to start my t3 cycle the same time i start my fina/bromo/winny?

 

[jatos]

This makes alot of sense and I compliment the amount of work that has gone into this thread.

I have a question though, How much of an effect would taking T3 along with Tren have on prolactin?

Fonz, you have cleared up the relation between TRH and Prolactin levels. So would continuing Tren after finishing a T3 bout be a NO NO? What do you think?

A selfish bump

 

[Fonz]

A selfish bump

Very astute observation.

Fina has LOWERED T3 levels, which are INDIRECTLY
responsible for the Fina Gyno.

Now, what happens if we ADD 25mcg's of T3/day.

Hmmmm.....now things get interesting.

T3 levels go BACK TO NORMAL. TRH goes back to
normal, but TSH drops(no real problem).

Result: INCREASED Anabolism at the expense
of a portion of Fina's powerful anti-glucocorticoid
action.

BUT, you ALSO get an extra FAT-BURNING effect from the T3.

So, by adding T3 you INCREASE anabolism, fat-burning
but reduce anti-catabolism. HOWEVER, you also
reduce TRH, and therefore PROLACTIN LEVELS.

So, by adding T3 you will reduce the prolactin increase
caused by the trenbolone.

Add Bromocriptine to the mix, and your chances of getting
Fina gyno are reduced to like 0.0000001%.

Fonz

 

[perfectspecimen]

would pergolide (permax) be a better choice instead ofbromocriptine?

 

[perfectspecimen]

bump

 

[Golfer18--old]

I just got off fina for eight weeks. Im only on winstrol for the last two weeks. I havent had any prolactin problems (knocking on wood) I got some bromo in case. Im running liquidex at 1mgED and some eca's, nyc's, and yohimbe. I dont have any problems this time but then again my problems started THREE months after i discontinued Fina on my last cycle.

 

[perfectspecimen]

pergolide or dostinex instead of bromo, which is the better choice