Fro. Prolactin, PR, Fina. Help with answers

[DrZaius]

Golfer18, what did you use to finally end your problem?
I also had a little rebound effect with puffy nips about 2 months after my Abombs and Eq cycle.

Fina and Abombs progesterone sides would be the same associated with gyno correct?


Peac
DrZ

 

[thejonboy]

Bump

 

[mvmaxx]

I’m going to do an experiment to gage the effectiveness of vitex on persistent gyno caused by Tren (My own).
I have ordered Vitex and will take 1500 mg ED. If Vitex is effective than I should see some resolution. If my mass does not shrink than I will try Bromocriptine which I have also ordered. If the tissue growth is in fact being influenced by this feedback loop than I should see some resolution with either or. If the vitex does not work and the Bromo does, than it will be safe to say the Vitex is effective in inhibiting estrogen through elevations in progesterone, where people have reported improvement through its use. If the Vitex works than it will be safe to say that it does in fact lower prolactin.

Hope that makes sense. I will keep the results posted.

I just got done reading through this entire thread....AGAIN and I noticed that both fro and LONE_AZ said they were going to try experiments on themselves and post the results.

So guys, any updates?? I know LONE_AZ is getting surgery done so I assume it didn't work. I just want to know if the bromo had any effect.

fro's thread-

Originally posted by frorider6
I'm going to drop the Vitex and Nolva and keep Fina at 37.5 mg ED (as well as Proviron 50 mg ED). But as soon as I can get some Bromo I'll up the dose back to 75 mg ED. I'll try to keep everyone informed of my progress.

 

[perfectspecimen]

Here is what I am doing with my Fina cycle:

for 2 weeks prior i am using bromocriptine at 1.25mg a day
then starting the fina at 75mg/ed and winny at 75mg/ed for 8 weeks with dostinex at .25mg twice a week and vitex at 3g/ed

then 1 week after that i am using bromocriptine again at 1.25mg/ed

and i am also running t3 with my fina

 

[Golfer18--old]

Golfer18, what did you use to finally end your problem?
I also had a little rebound effect with puffy nips about 2 months after my Abombs and Eq cycle.

Fina and Abombs progesterone sides would be the same associated with gyno correct?


Peac
DrZ

Liquidex stopped most of my problems...........

I also got some bromocriptine.

 

[jboldman]

But nandi, the study cited by panerai above noted NO change in prolactin levels after administration of TA. The only tissue that I am aware of that TA binds to the pr is the Bovine PR in the uterus. And even if it binds to it, do wee know if it as an agonist?

jb

-Fina binds to the progesterone receptor in certain tissues
-Progesterone stimulates the production of prolactin
-Prolactin and/or estrogen are the causes of gyno
-RU-486 blocks progesterone and reduces prolactin
-Progesterone downregulates estrogen receptors
-Blocking progesterone with RU-486 upregulates the estrogen receptor
-RU-486 causes gyno.

For references see my post (nandi12) on this topic at Triedia:

http://www.triedia.com/forum/showthread.php?s=&threadid=11926

 

[LONE_AZ]

The bromo help some vitex did not do shit. I think my case is to advanced to be of any measure of the effectiveness of Bromocriptine or Vitex.

 

[nandi12]

If you read my entire post you will see that unlike in humans, TRH does not influence prolactin release in sheep. (1)

I suggested two different theories that might explain how tren could elevate prolactin, if in fact it really does. One involved progesterone receptor binding, and the other (in case tren is not a progesterone receptor agonist) involved TRH elevation.


(1) Endocrinol 1988 Apr;117(1):115-22

Release of prolactin is independent of the secretion of thyrotrophin-releasing hormone into hypophysial portal blood of sheep.

Thomas GB, Cummins JT, Yao B, Gordon K, Clarke IJ.
Medical Research Centre, Prince Henry's Hospital, Melbourne, Australia.

 

[ambulancechaser]

Shameless bump to what I think is a very important thread. Did someone post a summary? I've been reading that fucking thing for over 1.5 hours and I think I know less than when I started. I'm going blind looking at the monitor.

I am surprised, however, at the level of civil debate and discussion. I don't think there was 1 flame in there.

If someone can post a summary or point me in the right directions, that would be awesome. It seems that the answer is: "Nobody Knows." That would suck.

 

[LONE_AZ]

Nandi,

I suspect that Prolactin Inhibiting Factor (PIF) which inhibits the release of prolactin and is purported to be dopamine, is effected in some way. I'm not sure how but maybe the mechanism by which PIF works does not function properly. Quite possibly locking the dopamine receptors in the pituitary or a possible down-regulation.