The only thing that is going to make a difference is how much pain will come with the shot. I shoot in my glute.... doesnt feel like anything. Exspect to be sore after your first for a couple days. Then its smooth sailing. PCT=Post Cycle Therapy. Read the post cyce therapy stickys they are long but you will get a good idea on what they are and how they work. Get a platiunum Membership and use the search and READ. It will take awhile but it will be worth it.