Femara Questions

[kbrkbr]

femara is so strong that will kill your mojo .
Victor

What do you mean by that? Sorry, I'm an old fart.

 

[VeteranNewbie88]

What do you mean by that? Sorry, I'm an old fart.

He means it will kill your sex drive my friend....Triple J, thanks for the input....unfortunately, I have no idea where to find Aromasin, I have also been searching in vain for Dostinex which is another story...anyway, thanks for all the inout guys...I believe I will try Femera at 1mg every other day....adjusting this dosage depending on how I react...

 

[kbrkbr]

He means it will kill your sex drive my friend....Triple J, thanks for the input....unfortunately, I have no idea where to find Aromasin, I have also been searching in vain for Dostinex which is another story...anyway, thanks for all the inout guys...I believe I will try Femera at 1mg every other day....adjusting this dosage depending on how I react...

All these years in the game and I never knew femera could hurt your libido. I wonder why it does this.

Have you tried mastersmarketing for your dostinex?

 

[einstein1905]

estrogen is a very individual issue that each user needs to learn how to address to suit his own needs ... one's conversion of T to E will vary based on age, bodyfat%, genetics, etc. - personally i hate any bloat and prefer to run an anti-a on any T cycle. I try to take as little ant-a as possible to minimize bloat. once bloat is controlled, i find there is no need for further protection. i also believe nolva would be counter-productive since it may act to raise SHBG levels, and I believe this would be counter-productive. if you believe as i do, that free T is important, you will want to keep your e levels in line, too since estrogen directly acts to increase levels of SHBG. also i believe the danger to lipid levels from moderate usage of anti-a's is somewhat exaggerated. the harm to lipid values, on the typical AAS cycle, is more directly caused by the anabolics (just about anything other than T). granted nolvadex can probably help with this lipid situation somewhat, but the issue is probably best addressed in other ways: diet and nutritional supplements.

Nolva doesn't reaise SHBG in any study I've ever seen. i do agree that using JUST enough of an AI to prevent excessive bloat/hypertension is perfect. however, estrogen is incredibly anabolic, so suppressing estrogen beyond preventing excessive bloat is counterproductive. That's why nolva allows one to maintain a supraphysiological estrogen level w/o sides.
Also, i rely on androgens themselves to lower SHBG. I'll always add in proviron in th elatter part of a cycle to lower SHBG levels and raise the % of bioavailable AAS.


Another thing....using exemestane alone is the same theory as overdoing a class II AI.....you're suppressing estrogen too much.....why not reap the benefits of estrogen?

Nolva both raises HDL and lowers LDL. There's no good reason not to use it IMO'.

comparing adex and femara, most people who have used both, report femara to be considerably stronger in effect and I agree with this. I have read this is because femara penetrates the adipose cells better thus inhibiting their aromatase activity better than adex. some report that femara is too strong which can have ill effects on sex drive - I believe this issue is just a matter of finding the right dosage level. Since adex and femara are similiary priced, and femara is stronger and thus can be effective in doses as low as .5mg eod, I find that it is slightly more cost effective to run femara.

 

[Triple J]

FYI I refer you to pubmed, seach on nolvadex SHBG:
http://www.ncbi.nlm.nih.gov/entrez/...ve&db=pubmed&dopt=Abstract&list_uids=10810443
http://www.ncbi.nlm.nih.gov/entrez/...ve&db=pubmed&dopt=Abstract&list_uids=11430992

also there are studies indicating nolvadex decreases IGF1
http://www.ncbi.nlm.nih.gov/entrez/...ve&db=pubmed&dopt=Abstract&list_uids=11844826
http://www.ncbi.nlm.nih.gov/entrez/...ve&db=pubmed&dopt=Abstract&list_uids=10848871

I do not like to over-rely on the studies, experience is just as important, perhaps more so, as no studies are performed on AAS taking athletes. Since I have experienced the downside of estrogenic sides I prefer to use what I consider to be the more active management approach offered by anti-a's.

 

[einstein1905]

FYI I refer you to pubmed, seach on nolvadex SHBG:
http://www.ncbi.nlm.nih.gov/entrez/...ve&db=pubmed&dopt=Abstract&list_uids=10810443
http://www.ncbi.nlm.nih.gov/entrez/...ve&db=pubmed&dopt=Abstract&list_uids=11430992

also there are studies indicating nolvadex decreases IGF1
http://www.ncbi.nlm.nih.gov/entrez/...ve&db=pubmed&dopt=Abstract&list_uids=11844826
http://www.ncbi.nlm.nih.gov/entrez/...ve&db=pubmed&dopt=Abstract&list_uids=10848871

I do not like to over-rely on the studies, experience is just as important, perhaps more so, as no studies are performed on AAS taking athletes. Since I have experienced the downside of estrogenic sides I prefer to use what I consider to be the more active management approach offered by anti-a's.

One of the two articles regarding SHBG is not available online in full text, but it states that SHBG levels remained w/in normal ranges but were "significantly elevated", which usually implies that it was a minor increas......statistically significant changes are alluded to in terms of "significant change" as opposed to the actual % change when that change isn't a large value. The 2nd study was in vitro but did cause a practically signifiacnt rise in SHBG of ~50%. The dose of tamoxifen used was likely a dose equivalent to therapeutic doses, so that's legit. One thing to counter this is that, although estrogens do increase SHBG (and apparently synthetic estrogens too), androgens lower SHBG levels, so AAS users have the advantage of supraphysiological androgen levels as well.....potentially to fully counter the SHBG effects by nolva and then some.


As for the IGF-1 implications, they refer to serum IGF-1 levels, which are relatively unimportant to us IMO. It's the intramuscular synthesis of IGF-1 (IGF-1Ea) that's important to us. I have seen the study that implicates tamoxifen acting at the level of the pituitary on GH release, but most studies are also done in breast cancer patients, people who have abnormally high IGF-1 synthesis in mammary fat pads, which is a phenotypical characteristic of breast cancer.....since tamoxifen has a high affinity for breast ERs, it's very likely that a good deal of the reduce3d serum IGF-1 also results from decreased IGF-1 synthesis in mammary fat pads and other localized stromal cells.


I do agree with you that the pros of tamoxifen outweigh the cons, especially considering our typical androgen levels, and I also use exo GH and IGF-1, so that issue is null and void for me.

 

[Smokescreen]

Dostinex here's 2 sites.http://www.buy-dostinex.com/buy-dostinex/Buy_Dostinex_Cabergoline_Cabaser.asp
http://www.shoprxonline.com/dostinex/

And Femera http://www.pumpnpose.com/

I've always used Adex and liked the results. Loved femera results way better though. Except for the fact that it killed my sexual desires and it made my bones and joints ache. I'm now using Aromasin. Seems to work ok. Not great but ok. At least my joints don't hurt. And now I do desire sex. Still up in arms between Adex and Aromasin though.

 

[boogersnax]

Anytime you reduce the level of total estrogen you are going to affect cholesterol levels.

PEACE

 

[einstein1905]

Anytime you reduce the level of total estrogen you are going to affect cholesterol levels.

PEACE

Thank you....I completely agree......the two studies showing aromasin not affecting HDL will be anomalies in the grand scheme of things, once more studies are done. Lowering systemic estrogen lowers HDL....that's it.

 

[nbk]

I read that if I take nolvadex while on femara, the amount of femara in my system will drop somewhat? What gives