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East Germans sue over Oral-Turinabol
- Thread starter aussiebeef
- Start date
landser
New member
axe3 said:
I think what happened with Ben Johnson, was that he was supposed to be taking Furuzabol, a Japanese steroid, to avoid failing a drug test as Furuzabol was not tested for at that time. However, the doctor he was getting his AAS from, decided to give ben winstrol instead of furuzabol because it was cheaper, and he could make more profit off of ben by doing this. Thus ben failed his test.
macrophage69alpha
New member
paridhm said:
yes, anadrol has been linked. But its not neccesarily abuse nor cause, its more likely that anadrol is a "trigger", the underlying mechanism was already present in the individuals.
macrophage69alpha
New member
some light reading
Cancer. 1999 Oct 15;86(8):1571-5. Related Articles, Links
Comment in:
Cancer. 2000 May 1;88(9):2195-7.
Intratesticular leiomyosarcoma in a young man after high dose doping with Oral-Turinabol: a case report.
Froehner M, Fischer R, Leike S, Hakenberg OW, Noack B, Wirth MP.
Department of Urology, Universitaetsklinikum "Carl Gustav Carus," Technical University of Dresden, Dresden, Germany.
BACKGROUND: Androgenic anabolic steroids have been suspected of activity as carcinogens in the development of carcinoma and angiosarcoma of the liver and adenocarcinoma of the prostate. Although the proliferation of smooth muscle cells is stimulated by sexual steroids, to the authors' knowledge a possible relation between androgenic anabolic steroids and the development of leiomyosarcoma has not previously been reported in humans. METHODS: A 32-year-old man underwent right radical orchiectomy for a tumor of the upper pole of the right testicle. Routine histopathologic examination and immunohistochemical staining were performed. RESULTS: The tumor was identified as an intratesticular leiomyosarcoma based on its typical growth pattern and the characteristic immunohistochemical staining profile. The patient reported a 5-year history of systematic use of high dose Oral-Turinabol (4-chloro-1-dehydro-17alpha-methylteststerone) that began at age 18 years and stopped approximately 9 years before presentation. CONCLUSIONS: The rarity of intratesticular leiomyosarcoma, the experimental induction of similar tumors in animals by androgens and estrogens, and the unusually young age at presentation of the patient in the current study support the hypothesis that high dose doping with androgenic anabolic steroids could have played a cocarcinogenic role in the development of the tumor in this case.
Cancer. 1999 Oct 15;86(8):1571-5. Related Articles, Links
Comment in:
Cancer. 2000 May 1;88(9):2195-7.
Intratesticular leiomyosarcoma in a young man after high dose doping with Oral-Turinabol: a case report.
Froehner M, Fischer R, Leike S, Hakenberg OW, Noack B, Wirth MP.
Department of Urology, Universitaetsklinikum "Carl Gustav Carus," Technical University of Dresden, Dresden, Germany.
BACKGROUND: Androgenic anabolic steroids have been suspected of activity as carcinogens in the development of carcinoma and angiosarcoma of the liver and adenocarcinoma of the prostate. Although the proliferation of smooth muscle cells is stimulated by sexual steroids, to the authors' knowledge a possible relation between androgenic anabolic steroids and the development of leiomyosarcoma has not previously been reported in humans. METHODS: A 32-year-old man underwent right radical orchiectomy for a tumor of the upper pole of the right testicle. Routine histopathologic examination and immunohistochemical staining were performed. RESULTS: The tumor was identified as an intratesticular leiomyosarcoma based on its typical growth pattern and the characteristic immunohistochemical staining profile. The patient reported a 5-year history of systematic use of high dose Oral-Turinabol (4-chloro-1-dehydro-17alpha-methylteststerone) that began at age 18 years and stopped approximately 9 years before presentation. CONCLUSIONS: The rarity of intratesticular leiomyosarcoma, the experimental induction of similar tumors in animals by androgens and estrogens, and the unusually young age at presentation of the patient in the current study support the hypothesis that high dose doping with androgenic anabolic steroids could have played a cocarcinogenic role in the development of the tumor in this case.
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