tommboy said:Does Aleve (naproxim) inhibit protein synthesis at all like advil or tylenol does?
tommboy said:omg dude how much does it do ? Like if Im on gear will I notice the effects if im takin aleve everyday?
tommboy said:doc said to take it every day for a few weeks (2 twice daily)
It is for my shoulder and it is helping a great deal but this REALLY fricken sucks that is hurts protein synthesis why is this!!!!!!!!?????KD1 said:Do what the doctor tells you. It may reduce your gains slightly, but its not going to make your cycle worthless or anything.
KD1 said:Something to do with inhibiting certain inflamitory messengers that trigger muscle growth.
Listen, Ive been running 400mg Ibuprofin almost every day for a while now. Sometimes 800mg. Ive made great gains in strength and size both on and off cycle. I dont take it immedietly before or right after training.
If I take it in the evening, its 3-4 hours after working out. If I take it in the morning, its 6-8 hours before training. I dont think its affecting me that much, maybe 20% or something like that.
You have to look at the big picture. If your joints/tendons cant heal from your training sessions, you cant work out, so whats going to build more muscle - not working out or taking Ibuprofin and working out?
tommboy said:It is for my shoulder and it is helping a great deal but this REALLY fricken sucks that is hurts protein synthesis why is this!!!!!!!!?????
KD1 said:Man, I have the best doctor in the area looking at my injury. He is the team orthopedic for two NHL teams, and has over a dozen name pro-players in football and baseball he has operated on. Ive gone through physical therapy, 2 months of if following a cast for 4 weeks and a sling for 8 more.
This is his course of action. My injury is getting better, and its a 6+ month recovery time from surgery, and that may not make it any better than it is. Gradually over time Im using less and less meds, and my arm is getting stronger and stronger. Things like this dont heal overnight. If I completly blow it out, he will operate asap, but until then this is the best treatment.
njmuscleguy said:Well, all I can say is I hope things turn out for the best for you! ... I'm not trying to sound negative, but just because a doctor is well-known or because he's a "doctor to the stars", doesn't mean that they're always providing the most appropriate care... some of those doctors are sometimes known to just give some meds or injections and then everything is hunky-dory (for a while anyway).... Good luck bro!
KD1 said:Thanks, Im not trying to argue for him but I mean just look at it from my perspective, who should I believe - a doctor with his credentials or some well meaning dude on a messageboard?
tommboy said:yes guys this is what my doctor told me to do he said it was probably Tendonitis and then only do it for 4 weeks and then come see him. And Naproxim isnt a NSAID i dont think it is different then advil thats what he said anyways its not a pain reducer just a anti inflammatory
CaddysNJuice said:Naproxen blocks the enzyme that makes prostaglandins (cyclooxygenase ), resulting in lower concentrations of prostaglandins. As a consequence, inflammation, pain and fever are reduced. Naproxen was approved by the FDA in December, 1991.
Naproxen may increase the blood levels of lithium (Eskalith). Naproxen may reduce the blood pressure lowering effects of blood pressure medications. This may occur because prostaglandins play a role in the regulation of blood pressure.
When naproxen is used in combination with aminoglycosides (e.g., gentamicin) the blood levels of the aminoglycoside may increase, presumably because the elimination of aminoglycosides from the body is reduced. This may lead to more aminoglycoside-related side effects.
Individuals taking oral blood thinners or anticoagulants (e.g., warfarin) should avoid naproxen because naproxen also thins the blood, and excessive blood thinning may lead to bleeding.(Such as DBol)
No where in the Harvard Journal does it say decreases protein synthesis. You are more likley to find that milk thistle inhibits protein synthesis more than this stuff.....
njmuscleguy said:also, shoulder pain is often due to the secondary muscles becoming weaker than primary muscles.... so you can do a look-up online for shoulder (strength-building) exercises that will strengthen those smaller, secondary muscles
GoldenDelicious said:hiya. pharmacist.
i dispense nsaids to the elderly, who cannot afford any protein loss (or they start falling down, breaking hips, and dying) and in all the time i was in a very prestigious pharmacy school, taught by academic pharmacists who were nationally and world renowned for their expertise, protein loss was NEVER mentioned as something to think about when dispensing them.
imo their effect on protein is overstated.
njmuscleguy said:very good to know! curious though as to the longer-term effects of using NSAID's? particularly the liver...the stomach...etc.
Quadsweep said:I did not know any of these retard lean mass gains...I actually do not see any reason why any of them would....where did this come from?
Quad
KD1 said:Thanks, Im not trying to argue for him but I mean just look at it from my perspective, who should I believe - a doctor with his credentials or some well meaning dude on a messageboard?
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