cocaine

[spongebob]

Much much more, heroin is a narcotic. Different addictive properties.

Meth does not f--k with the dopamine feedback loop like coke.

Live with a coke addict, tell me it's like pot. Imbecile.

not sure about the dopamine feedback look, but strictly from experience i would say your on to something.

example. i along with people i have partied with all exhibit the same comedown with coke.

you party all night and at the end of the night when the shit runs out and thier is absolutely no chance of getting anymore, you can literally see the immediate crash on peoples faces. they panic and exhaust all measures of getting anymore. they are immediately depressed.

not the same with E, meth, alcohol, etc. from what i have observed.

as far as the dopamine feed back loop causing stronger addiction, im not sure, i believe there are too many other factors involved. there has to be something within each individual or groups of individuals. some people may not have a negative response to the fact that coke encourages your dopamine system to only want coke for the release.

 

[Lestat]

not sure about the dopamine feedback look, but strictly from experience i would say your on to something.

example. i along with people i have partied with all exhibit the same comedown with coke.

you party all night and at the end of the night when the shit runs out and thier is absolutely no chance of getting anymore, you can literally see the immediate crash on peoples faces. they panic and exhaust all measures of getting anymore. they are immediately depressed.

not the same with E, meth, alcohol, etc. from what i have observed.

as far as the dopamine feed back loop causing stronger addiction, im not sure, i believe there are too many other factors involved. there has to be something within each individual or groups of individuals. some people may not have a negative response to the fact that coke encourages your dopamine system to only want coke for the release.

the Bomb Squad is glad to see you back man.

 

[spongebob]

even with all that scientific shit.. an addict can actually die from trying to come off heroin.. i doubt its the same with coke..

not 100% sure about this but the only drug that can cause death from actual withdraws is alcohol.

 

[spongebob]

Coke is like Ritalin's big brother. While it is possible to OD on it, it's not as dangerous as its critics say it is. You'd have to be pretty stupid and take a lot to OD on it. It's not a safe drug, and could affect each user differently, but all in all it's just Ritalin with a little extra kick. And numbies.

i would clasify coke as ritalins cousin.

meth is the big brother of ritalin, adderall and that other ADD drug. if i remember correctly the only difference is the methyl group molecules. pure meth is actually prescribed for ADD.

 

[spongebob]

it has to do with the method of adminsitration.

The linings of the lungs are the fastest way to get a substance into the bloodstream. The speed at which a substance hits the brain is related to enhancing its addictive properties. This is why crack is more addictive than powdered cocaine; it hits the blood 25% faster.

Nicotine gets in the same way, so its already addctive properties are enhanced.

.

if crack is coke and coke is crack, and the brain treats them the same, then i would say that the method of administration may be the difference in the entensity of the high but not neccesarliy the addictive properties physically. probaly pshycologically.

in other words, the high is intense but it is shorter lived that snorting. so you have to do more to stay at baseline.

 

[Mastardo]

taking drugs IV is the fastest. period!

if you smoke anything it gets into the bloodstream thru your lung linings. from thier it travels to the brain. and then crosses the blood brain barrier. that is one step more than IV.

that is the route. so it makes 100% sense that the shortest route to the blood is in the BLOOD. IV.

i have never shot drugs, but ive smoked coke, crack and meth. the rush is not as immediate. it is usually 15 to 20 seconds after the hit.

IV users get the rush almost immediately, thats why you see IV junkies with the needle still in thier arm.

WRONG.

http://science.education.nih.gov/supplements/nih2/addiction/images/guide/fig3.6.gif

http://science.education.nih.gov/supplements/nih2/addiction/guide/lesson3-1.htm

"A drug that is inhaled (smoked) reaches the brain very quickly. The inhaled drugs go directly from the lungs into the left side of the heart, where they enter the arterial circulation that carries them to the brain. Marijuana and nicotine are examples of drugs that are commonly taken into the body by inhalation (smoking). The intensity of the effect of inhaled drugs may be slightly less than that for injected drugs because less of the drug is taken into the body; some of the drug will be exhaled with the rest of the components of the smoke. A drug that is injected intravenously also travels quickly to the brain, where it can exert its effects. The rapid passage of injected heroin, for example, brings a high risk of overdose."

15 to 20 seconds to feel a hit of inhaled meth? Try 2 seconds. IV rushes are more overpowering once they hit you from what I have heard (and seen, although not with heroin so none of them passed out), but not as immediate and not as steep or choppy.

 

[spongebob]

crack is coke

but there are a lot of strippers etc that i know (and know of) that do what they do at least partly due to their choice of drug.

quickest way around here to jump into bed with a stripper is to pull out a bag of coke at 3am and say lets go back to my place and do this.

over here, all you need is E, coke or meth. one of the three on your hook and your gonna reel in a stripper. seems like meth is fast become just as popular. its just a little harder to get.

 

[spongebob]

there is coke in crack but it is def not the same thing.. cocaine cooked with baking soda etc.. etc.. etc.. = crack.. the highs are completely different.. and the comedowns are completely different..

the highs are different because only because of the intensity. and the intensity dictates the comedown.

molecules are identical.

 

[spongebob]

it isnt just the administration - cut a long story short, when you boil cocaine with sodum bicarbonate, the resultant molecule (still cocaine, it hasnt changed much at all) can soak across the blood brain barrier much better than the original form - meaning that for the same dose of cocaine, more make it to the area of the brain where it exerts its effect.

all the dynamics change as well - the amount that soaks into blood, equilibrium between blood and the receptors in the brain etc etc.

.

IMO it sounds like you are just reinterating what Matt said.

he is talking about method of admin dictating the highs entensity and so are you.

 

[spongebob]

I know its a strange question but is there anything you can take/do to ease the come down from coke or are you fucked no matter what?

valium, xanax, or any other benzo will work fine.