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Bromocriptine: A new addition to the Gainskeeper Formula!!!
- Thread starter Fonz
- Start date
LewdTenant
New member
chakarov said:
hlaf life is 6 hours so it is important to take 2 doses per day.
Lewd
NEXT BIG THING!!
during researching Bromocriptine i found following useful info from some sites and t-mag: -
"As an aside, several medications are known to increase GH levels. Most of these medications are neuroendocrine (by extension used in psychiatry). These medications include Zolmitriptan, Clonidine, Apomorphine, Baclofen, Bromocriptine, Pergolide mesylate, L-692,429 and L-163,255 (compounds in development by Merck), ghrelin (a developmental drug) and other dopamine and GABA agonists. Please note that the duration of elevated GH from any of these medications isn't yet defined."
"There is some evidence that the antioxidant bromocriptine can facilitate L-Dopa by lowering the usual effective dose to half. This has sometimes been found to result in less long-term degeneration and sometimes seems to lead to repairs of damage to dopaminergic nerve cell layers [Teychenne 1983; Vance 1984]. (It should be noted that bromocriptine is structurally related to Hydergine, which may explain its antioxidant effects.)"
by Brock Strasser: -
"Well, Lyle has a new book out and I was fortunate enough to review this book before it was published and sold. The information contained in Bromocriptine — An Old Drug with New Uses (Lyle's new fat loss codex) may revolutionize the way we look at fat loss, dieting, and supplementing for both.
Bromocriptine has been around for over thirty years as a prescription treatment for Parkinson's Disease and other associated neurological deficits. It (and its newer analogs like cabergoline) has a solid track record in humans. It's a drug I'd have little reservations about using in low dosages for fat loss over extended periods of time because of its impressive safety profile. In fact, I'd certainly pick bromocriptine over clenbuterol (which I feel is useless), liothyronine, and the smorgasbord of other "diet drugs" that have become too commonplace in today's bodybuilding arsenal.
Lyle takes fat loss in an entirely new direction with his book. Traditional fat loss mantra maintains we need to stimulate the beta 1-2-3 and/or alpha 1-2 receptors to induce lipolysis. Either that or we have to tweak thyroid hormone levels up high enough to crank up basal metabolic rate and core body temperature. But Lyle looks at fat loss through a different perspective, that of the dopamine receptors (DA-1 and DA-2) and the current crop of dopaminergic agonists. "
by Cy Wilson: -
"Q: Is there anything a person can do to get his sex drive back after a cycle? Even with Clomid this seems to take a while.
A: If you simply want to increase the urge to have sex, then you can go with clomiphene along with bromocriptine or something like vitex which is found in Biotest's M. The reason is simply because these substances are dopamine agonists which can lower the production of prolactin (prolactin decrease sex drive and is often elevated after a cycle of Testosterone and other androgens). When prolactin is decreased, sex drive can increase rather dramatically. (There was even a case in the UK where a man sued the makers of bromocriptine since it gave him an uncontrollable sex drive.)
So why should we care about inhibiting prolactin secretion? Let me explain. First off, estrogen and prolactin are related in terms of their release. In other words, when estrogen rises, so does prolactin. Who gives a rat's ass? You should for a few reasons, one being that it decreases LH and Testosterone. There's also a good amount of evidence suggesting prolactin is partially responsible for the degree of sensitivity in terms of gonadal steroid feedback (negative feedback) and may even regulate the sensitivity of the gonads to stimulation by LH.
In one study researchers took eleven normal men and studied them both during hyperprolactinemia and hypoprolactinemia. What they found was that LH rose in a state of hypoprolactinemia. However, in men, it's been shown time and time again that elevated prolactin leads to decreased gonadotropin levels (LH).
Furthermore, in a study with men who had elevated prolactin levels, they decided to measure the effect of hCG (acts like LH) administration on Testosterone production. What they found was that in hyperprolactinemic men, their response to hCG administration (measured in terms of Testosterone levels) was significantly lower than that of men with normal prolactin levels. When they treated the individuals with hyperprolactinemia and reduced prolactin levels, they found the increase in Testosterone after hCG administration was much higher.
So you think your prolactin levels will never rise? Think again. If your Testosterone rises (and thus estrogen rises via conversion by the aromatase enzyme), your prolactin will rise as well. Furthermore, prolactin has been shown to rise in times of stress. As we know, the combination of everyday life and bodybuilding can produce a large amount of stress. On a side note, this once again confirms to me that methandrostenolone (D-bol) increases dopamine levels and thus increases sex drive."
"Bromocriptine also affects the most famous of all pituitary hormones- growth hormone (GH). Bromocriptine increases growth hormone secretion in individuals with normal growth hormone concentrations, but paradoxically suppresses GH secretion in some patients with acromegaly (a condition of excessive-production of GH). Studies indicate that bromocriptine does not affect the release of any other anterior pituitary hormones.
Due to its dopamine enhancement bromocriptine has even been cited as an aphrodisiac, although little effort has been made to study and confirm this action. There have been several reports of “better controlled” orgasms and “almost orgasms” before the real orgasm occurs. If any countries allow for more medical categories such as “weak orgasm syndrome” or perhaps “clinical sex-drive loss” then dopamine agonists such as bromocriptine are going to receive a lot of attention from the pharmaceutical manufacturers, especially in the wake of Viagra sales.
Another interesting clinical study administered a component of tobacco called DMBA to rats at a level where it is known to be very effective in producing breast cancer. However, rats that had been pretreated with bromocriptine completely avoided any cancer development. Bromocriptine therefore appears to also offer itself as a very potent free radical quencher.
One of the most recent studies indicates that bromocriptine may be a candidate for the treatment of Type-2 diabetes. This is because bromocriptine has been shown to suppress lipogenesis and improve glucose tolerance and insulin resistance.
One animal study suggested that a further action of bromocriptine is to alter CNS (central nervous system) regulating metabolism and as such has another important use in helping to prevent weight gain (this would be in addition to its improvement of diabetic conditions).
Dosages, Side Effects, Contraindications
Bromocriptine is a very potent substance and it mustn’t be used by pregnant or lactating women unless under the guidance of a physician. Side effects include nausea, dizziness, lowering of blood pressure, hypotension and confusion. The first three are relatively common, especially when undertaking initial use. It is also known to increase fertility, and thus “extra care” and contraception is advised where necessary.
It does contraindicate with psychoactive and hypotensive drugs and other dopamine enhancing drugs (such as deprenyl and L-dopa etc) should only be administered concurrently under a physician’s guidance. Its effects can also be exaggerated when combined with other ergots including Hydergine and nicergoline.
Overall, there is little need to exceed a dosage in excess of 1.25mg or 2.5mg daily for most people unless treating a serious medical disorder (and therefore only under a physician’s guidance). Bromocriptine has a wide and diverse range of clinically applications, it should be considered to only be an anti-aging medicine for the serious longevist."
"As an aside, several medications are known to increase GH levels. Most of these medications are neuroendocrine (by extension used in psychiatry). These medications include Zolmitriptan, Clonidine, Apomorphine, Baclofen, Bromocriptine, Pergolide mesylate, L-692,429 and L-163,255 (compounds in development by Merck), ghrelin (a developmental drug) and other dopamine and GABA agonists. Please note that the duration of elevated GH from any of these medications isn't yet defined."
i am going tomorrow to pharmacy to get one for me
during researching Bromocriptine i found following useful info from some sites and t-mag: -
"As an aside, several medications are known to increase GH levels. Most of these medications are neuroendocrine (by extension used in psychiatry). These medications include Zolmitriptan, Clonidine, Apomorphine, Baclofen, Bromocriptine, Pergolide mesylate, L-692,429 and L-163,255 (compounds in development by Merck), ghrelin (a developmental drug) and other dopamine and GABA agonists. Please note that the duration of elevated GH from any of these medications isn't yet defined."
"There is some evidence that the antioxidant bromocriptine can facilitate L-Dopa by lowering the usual effective dose to half. This has sometimes been found to result in less long-term degeneration and sometimes seems to lead to repairs of damage to dopaminergic nerve cell layers [Teychenne 1983; Vance 1984]. (It should be noted that bromocriptine is structurally related to Hydergine, which may explain its antioxidant effects.)"
by Brock Strasser: -
"Well, Lyle has a new book out and I was fortunate enough to review this book before it was published and sold. The information contained in Bromocriptine — An Old Drug with New Uses (Lyle's new fat loss codex) may revolutionize the way we look at fat loss, dieting, and supplementing for both.
Bromocriptine has been around for over thirty years as a prescription treatment for Parkinson's Disease and other associated neurological deficits. It (and its newer analogs like cabergoline) has a solid track record in humans. It's a drug I'd have little reservations about using in low dosages for fat loss over extended periods of time because of its impressive safety profile. In fact, I'd certainly pick bromocriptine over clenbuterol (which I feel is useless), liothyronine, and the smorgasbord of other "diet drugs" that have become too commonplace in today's bodybuilding arsenal.
Lyle takes fat loss in an entirely new direction with his book. Traditional fat loss mantra maintains we need to stimulate the beta 1-2-3 and/or alpha 1-2 receptors to induce lipolysis. Either that or we have to tweak thyroid hormone levels up high enough to crank up basal metabolic rate and core body temperature. But Lyle looks at fat loss through a different perspective, that of the dopamine receptors (DA-1 and DA-2) and the current crop of dopaminergic agonists. "
by Cy Wilson: -
"Q: Is there anything a person can do to get his sex drive back after a cycle? Even with Clomid this seems to take a while.
A: If you simply want to increase the urge to have sex, then you can go with clomiphene along with bromocriptine or something like vitex which is found in Biotest's M. The reason is simply because these substances are dopamine agonists which can lower the production of prolactin (prolactin decrease sex drive and is often elevated after a cycle of Testosterone and other androgens). When prolactin is decreased, sex drive can increase rather dramatically. (There was even a case in the UK where a man sued the makers of bromocriptine since it gave him an uncontrollable sex drive.)
So why should we care about inhibiting prolactin secretion? Let me explain. First off, estrogen and prolactin are related in terms of their release. In other words, when estrogen rises, so does prolactin. Who gives a rat's ass? You should for a few reasons, one being that it decreases LH and Testosterone. There's also a good amount of evidence suggesting prolactin is partially responsible for the degree of sensitivity in terms of gonadal steroid feedback (negative feedback) and may even regulate the sensitivity of the gonads to stimulation by LH.
In one study researchers took eleven normal men and studied them both during hyperprolactinemia and hypoprolactinemia. What they found was that LH rose in a state of hypoprolactinemia. However, in men, it's been shown time and time again that elevated prolactin leads to decreased gonadotropin levels (LH).
Furthermore, in a study with men who had elevated prolactin levels, they decided to measure the effect of hCG (acts like LH) administration on Testosterone production. What they found was that in hyperprolactinemic men, their response to hCG administration (measured in terms of Testosterone levels) was significantly lower than that of men with normal prolactin levels. When they treated the individuals with hyperprolactinemia and reduced prolactin levels, they found the increase in Testosterone after hCG administration was much higher.
So you think your prolactin levels will never rise? Think again. If your Testosterone rises (and thus estrogen rises via conversion by the aromatase enzyme), your prolactin will rise as well. Furthermore, prolactin has been shown to rise in times of stress. As we know, the combination of everyday life and bodybuilding can produce a large amount of stress. On a side note, this once again confirms to me that methandrostenolone (D-bol) increases dopamine levels and thus increases sex drive."
"Bromocriptine also affects the most famous of all pituitary hormones- growth hormone (GH). Bromocriptine increases growth hormone secretion in individuals with normal growth hormone concentrations, but paradoxically suppresses GH secretion in some patients with acromegaly (a condition of excessive-production of GH). Studies indicate that bromocriptine does not affect the release of any other anterior pituitary hormones.
Due to its dopamine enhancement bromocriptine has even been cited as an aphrodisiac, although little effort has been made to study and confirm this action. There have been several reports of “better controlled” orgasms and “almost orgasms” before the real orgasm occurs. If any countries allow for more medical categories such as “weak orgasm syndrome” or perhaps “clinical sex-drive loss” then dopamine agonists such as bromocriptine are going to receive a lot of attention from the pharmaceutical manufacturers, especially in the wake of Viagra sales.
Another interesting clinical study administered a component of tobacco called DMBA to rats at a level where it is known to be very effective in producing breast cancer. However, rats that had been pretreated with bromocriptine completely avoided any cancer development. Bromocriptine therefore appears to also offer itself as a very potent free radical quencher.
One of the most recent studies indicates that bromocriptine may be a candidate for the treatment of Type-2 diabetes. This is because bromocriptine has been shown to suppress lipogenesis and improve glucose tolerance and insulin resistance.
One animal study suggested that a further action of bromocriptine is to alter CNS (central nervous system) regulating metabolism and as such has another important use in helping to prevent weight gain (this would be in addition to its improvement of diabetic conditions).
Dosages, Side Effects, Contraindications
Bromocriptine is a very potent substance and it mustn’t be used by pregnant or lactating women unless under the guidance of a physician. Side effects include nausea, dizziness, lowering of blood pressure, hypotension and confusion. The first three are relatively common, especially when undertaking initial use. It is also known to increase fertility, and thus “extra care” and contraception is advised where necessary.
It does contraindicate with psychoactive and hypotensive drugs and other dopamine enhancing drugs (such as deprenyl and L-dopa etc) should only be administered concurrently under a physician’s guidance. Its effects can also be exaggerated when combined with other ergots including Hydergine and nicergoline.
Overall, there is little need to exceed a dosage in excess of 1.25mg or 2.5mg daily for most people unless treating a serious medical disorder (and therefore only under a physician’s guidance). Bromocriptine has a wide and diverse range of clinically applications, it should be considered to only be an anti-aging medicine for the serious longevist."
"As an aside, several medications are known to increase GH levels. Most of these medications are neuroendocrine (by extension used in psychiatry). These medications include Zolmitriptan, Clonidine, Apomorphine, Baclofen, Bromocriptine, Pergolide mesylate, L-692,429 and L-163,255 (compounds in development by Merck), ghrelin (a developmental drug) and other dopamine and GABA agonists. Please note that the duration of elevated GH from any of these medications isn't yet defined."
i am going tomorrow to pharmacy to get one for me
Last edited:
Now,
I don't understand why when you increase estrogen, you also get an increase in prolactin.
However, we should use either bromocriptine or cabergoline to suppress prolactin DURING the cycle too since if we use testosterone, it will aromatize into estrogen (more aromatization if we don't use anti aromatase)...
Maybe if sufficient aromatase enzyme is blocked during the cycle and not that many estrogen floating around, prolactin will be under control.
Spoud.
I don't understand why when you increase estrogen, you also get an increase in prolactin.
However, we should use either bromocriptine or cabergoline to suppress prolactin DURING the cycle too since if we use testosterone, it will aromatize into estrogen (more aromatization if we don't use anti aromatase)...
Maybe if sufficient aromatase enzyme is blocked during the cycle and not that many estrogen floating around, prolactin will be under control.
Spoud.
