Beta Receptors

[eliteandy]

What is in benadryl exactly that up regulated beta receptors when on say an ECA stack? The antihistamines?

 

[shawn_h001]

The only ingredient that is in it, diphenhydramine.

 

[centeroiler]

What is in benadryl exactly that up regulated beta receptors when on say an ECA stack? The antihistamines?

I was wondering this same thing. I believe it was Anthony Roberts that came up with this. I'll have to look that article up. It supposedly works.

 

[needtogetaas]

Cationic ampiphylic drugs are known for their ability to inhibit phospholipase A2. Benadryl (diphenhydramine) is a cationic ampiphylic drug.

Ergo, Benadryl slows desensitization of Beta receptors (i.e. Upgrades them) by inhibiting phospholipase A2, which is the enzyme that breaks down methylated phospholipids, and this action in turn keeps the phospholipid membrane stable, and thus keeps the receptors functioning properly. (7). This will allow you to use clen for much longer and it´ll still have the same effects. Also, since Benadryl is an anti-histamine, and histamines have a direct effect on beta-adrenoreceptors (not just Beta-2´s but all of them), using an anti-histamine will have a direct effect on reducing beta-receptor stimulation (16), and thus upregulating your beta-receptors.

 

[UncleBee]

Good info needto. I know alot of peeps that use antihistamines to help them sleep while on things like clen and albut. good thread bro!

 

[eliteandy]

So how much of a dose is needed to keep the receptors up?

 

[UncleBee]

50mg diphenhydramine hydrochloride QHS(once a day at bedtime). Some say in between your weeks of clen/ECA like week 3, but I use throughout. It does help you sleep good but be careful it can be Habit forming(not addictive though).