Battling Losing Natural Testosterone output while on Paxil

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http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=9539303&query_hl=1



http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=14764772&query_hl=1


http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15181056&query_hl=2


Here is what Paxil and other SSRI's do to Prolactin.

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=9443523&query_hl=3

This is mainly due to direct stimulation of the 5HT2 subtype of the serotonin receptor. Stimulation of this receptor will cause an increase in ACTH, Cortisol, Prolactin and acts as a governor on dopamine release in certain parts of the brain. Lowering prolactin is well known to increase LH receptor sensitivity.


This one is interesting because it shows a direct decrease in the direct metabolite of dopamine HVA which is a marker for decreased dopamine levels.

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=8274586&query_hl=2


This is also why wellbutrin an NDRI is so popular to add to SSRI treatment.

It would be interesting to see what a combo like dostinex and proviron would do.

I stand corrected. Those articles are great. Thanks very much for the insight.