Theoretically, yes. Food is the most anabolic supplement of all, and it's not even illegal.
Stuff like prohormones, steroids, glucose disposal agents, CNS stimulants, etc - will just speed you to your goal faster, they are not nescessary for muscle gain. People got plenty big and ripped in the old days before all of the above were popularized.
reg creatine doesnt seem to work for all--but if it doesnt there are those tricreatine malate mixes that work for those that are more resistant because they are more water soluble