Any way to decrease SHBG production?

[Big Rick Rock]

You guys know of any(proven) way to lower SHBG production?

 

[georgie24]

what is that?

 

[Big Rick Rock]

what is that?

.....an enzyme known as SHBG ( Sex Hormone Binding Globulin) and it's the deciding factor in how much testosterone you can use to build muscle and how much will remain in a "bound" unusable state. SHBG clings to testosterone and keeps it from working its magic. The more SHBG you have, the less "available" testosterone there'll be.....

 

[thx9000]

Aromasin.

 

[Big Rick Rock]

Aromasin.

Seriously dude?
Any data/studies avalible on that?

 

[SpeedFreak5]

^

 

[thx9000]

Seriously dude?
Any data/studies avalible on that?

FDA Clinical info

a dose-dependant decrease in SHBG has been observed with daily exemestane doses of 2.5mg or higher.

Comparative clinical pharmacology and pharmacokinetic interactions of aromatase inhibitors

A minor androgenic effect of exemestane is revealed by a significant suppression of sex hormone binding globulin (SHBG).

 

[Big Rick Rock]

FDA Clinical info

a dose-dependant decrease in SHBG has been observed with daily exemestane doses of 2.5mg or higher.

Comparative clinical pharmacology and pharmacokinetic interactions of aromatase inhibitors

A minor androgenic effect of exemestane is revealed by a significant suppression of sex hormone binding globulin (SHBG).

NICE!

K 4 U

 

[majutsu]

wow nice thread and post! Good thoughts. (for the guy who questioned) People (like Ronnie and Arnold) who flower with anabolics are thought to have certain genetic factors, such as lower SHBG binding, that enable them to get more anabolic activity from the same dose than others, to "waste" less. So the idea would be say test+aromisin = killer stack. I've heard dbol reduces SHBG, is this true thx or just a myth? And any more data on aromasin? And have you stacked aromasin with anything?

 

[MrMakaveli]

Didnt Nelson recommend certain herbs that lowered SHBG? Never knew if they actually worked though.