Please Scroll Down to See Forums Below Hey, currently on tren enth, oral methyl-DHT, letro, nolva and selegiline......ive been waking up and going to bed with some anxiety problems lately, anyone else get them on selegiline? I know its supposed to help with it (i take about 7mg ED), but ive been waking up unhappy and unable to sleep well....i hate it, very unhappy with my life situation even thought there is nothing to get upset about. Im getting my old seperation anxiety back..........anyone?
Anxiety from dopaminergics?
- Thread starter bigrand
- Start date
macrophage69alpha
New member
its definitely possible, though any and all of those can contribute to anxiety
njmuscleguy
New member
I'm not sure that selegiline causes anxiety... it didn't for me, and I'm prone to random panic attacks...it's not listed as a typical side effect either.... however, I did get headaches while on selegiline at 5mg ED, so I stopped taking it altogether.... if I were to guess, it could be any of the AAS you're taking... they could exacerbate anxiety
njmuscleguy
New member
have you done a cycle like this before? first time for anything? tren is known to cause anxiety in many
macrophage69alpha
New member
cabergoline is a specific D2 receptor agonist
macrophage69alpha
New member
kbrkbr said:
uncommon, but it can.
solidspine
New member
Stop taking it.
Over
Over
needtogetaas
New member
seems pretty simple if you want to find out if thats what is causing the problem.solidspine said:
krishna said:
Ive used tren before with no problem......the sel is the only new thing, its actually suppposed to help with depression/social anxiety.
Ill try bromo
As far as cabergoline, i think i read 15% can experience depression (ill find the source)...not to mention there have been SEVERAL links to it causing valve problems (regurgitation)....its an ergot alkaloid like what was used in fen-phen
macrophage69alpha
New member
bigrand said:
this is an issue witth all ergot derived drugs including bromocriptine. though it has only been found at higher end dosing ie. many people using these drugs for parkinsons use up to 6mg ED of cabergoline, as opposed to .5mg e4d typically used in these circles.
from NEJM "In patients with Parkinson's disease, the usual daily dose ranges from 2 to 6 mg, whereas in hyperprolactinemia, the weekly dose ranges from 0.25 to 3.5 mg. So far, fibrotic reactions and valvular heart disease due to the use of ergot dopamine agonists have been reported almost exclusively in patients with Parkinson's disease"
with bromocriptine up to 56mg per day is used in parkisons. 2.5mg is high end for most, most bodybuilders use .65mg to 1.25mg
basically dosing cabergoline at 12-42mg/week vs. maybe 2mg per week(in high dose users)
macrophage69alpha
New member
btw- it is still something to consider, if only in passing, in making your dopaminergic choice, however that being said the risk is likely extremely minimal at the dosages commonly used for prolactin inhibition.
macrophage69alpha said:
I think the incidence of valvular damage from bromo was like 17 in 10000....not enough evidence to make a real good comparison, but high dose cabergoline didnt look good....perhaps ill try it at a anti-prolactin dose......suggestion Macro (QD or QOD)?
I would try Norprolac as its not derived from ergot alkaloids...but its too hard to find.
There are just too many other variables with selgeline as its a MAO-B inhibitor under 10mg QD, i know its not the tren, ran tren before with no probs, not to mention, its too early for the tren enth to kick in.
One more thing Mac, do you know of the body clearence rate of selegiline, or at least time table for MAO-B levels to return to normal after stopping use? Im having a time trying to find diffiniative info on it.....its not as easy as being metabolized and excreted, ive read 2 weeks?
Sels 2 metabolites, meth-amphetamine and amphetamine dont interact well with caffeine.....i dont want to jump start anything else until i know my levels are normalized......i stopped the selegiline about 2 days ago.
Sels 2 metabolites, meth-amphetamine and amphetamine dont interact well with caffeine.....i dont want to jump start anything else until i know my levels are normalized......i stopped the selegiline about 2 days ago.
macrophage69alpha
New member
if you are just taking caffiene dont worry about it, often take plenty of caffeine with up to 20mg selegiline daily.
2 weeks is the "industry" word on clearance... would say generally 3-5 days is sufficient unless taking high doses or taking something that is highly contraindicated
2 weeks is the "industry" word on clearance... would say generally 3-5 days is sufficient unless taking high doses or taking something that is highly contraindicated
pitbullrocco
New member
http://www.selegiline.com/
http://www.selegiline.com/refs/index.html
the good drug guide......good reading
http://www.selegiline.com/refs/index.html
the good drug guide......good reading
I take Dostinex (in VERY low dose) 0.5mg/wk. Shit is amazing. Feel good. Horny as hell. Getting some bad press for heart valve sides. BUT only in Parkinson's patients, at much higher doses. And only ONE study. This shit is like a happy / horny pill. And a must with Deca.
I don't know bro, but Tren can make you pretty crazy. Just my 2cents.
Source: http://www.medicinenet.com
GENERIC NAME: CABERGOLINE - ORAL (kah-BURG-oh-leen)
BRAND NAME(S): Dostinex
Medication Uses | Other Uses | How To Use | Side Effects | Precautions | Drug Interactions | Overdose | Notes | Missed Dose | Storage
USES: This medication is used to treat certain hormone problems (excess prolactin). The drug is used to reduce or prevent breast milk production, except after childbirth (postpartum).
OTHER USES: This drug may also be used for Parkinson's disease, prolactin-producing tumors and to adjust various hormone levels in certain diseases (ovarian diseases).
HOW TO USE: This drug is taken by mouth twice weekly. Dosage is adjusted generally at 4 week periods based on blood tests (prolactin). Follow all instructions.
SIDE EFFECTS: Unusual weakness or fatigue, nausea or vomiting, constipation, headache, dizziness, drowsiness, tingling or numbness sensation may occur. If these persist or worsen, notify your doctor. Unlikely but report promptly: mental or mood changes. Very unlikely but report promptly: fainting, swelling of feet or ankles, breast pain, menstrual changes, vision problems. If you notice other effects not listed above, contact your doctor or pharmacist.
PRECAUTIONS: Before using this drug, tell your doctor your medical history, including: allergies (especially drug allergies), liver disease, psychiatric illness, uncontrolled high blood pressure, high blood pressure during pregnancy. Limit alcohol as it may aggravate side effects of this drug. Caution performing tasks requiring alertness, such as driving. To avoid dizziness and lightheadedness when rising from a seated or lying position, get up slowly. Tell your doctor if you are pregnant before using this medication. It is not known if this drug is excreted into breast milk. Because of the potential risk to the infant, breast-feeding while using this drug is not recommended. Consult your doctor before breast-feeding.
DRUG INTERACTIONS: Tell your doctor of all nonprescription and prescription medication you may use, especially of: blood pressure drugs, dopamine blockers (e.g., metoclopramide, antipsychotics such as chlorpromazine, haloperidol). Also report the use of drugs that cause drowsiness such as: sedatives, sleeping pills, narcotic pain relievers (e.g., codeine), anti-anxiety medications, antidepressants, muscle relaxants, anti-seizure medications, certain antihistamines (e.g., diphenhydramine). Do not start or stop any medicine without doctor or pharmacist approval.
OVERDOSE: If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly. Symptoms of overdose may include mental/mood changes, nasal congestion, fainting, lightheadedness, or irregular heartbeat .
NOTES: Do not share this medication with others.
MISSED DOSE: If you miss a dose, contact your doctor promptly to establish a new dosing schedule.
STORAGE: Store at room temperature between 68 and 77 degrees F (20-25 degrees C) away from light and moisture.
Last Editorial Review: 3/2/2005
I don't know bro, but Tren can make you pretty crazy. Just my 2cents.
Source: http://www.medicinenet.com
GENERIC NAME: CABERGOLINE - ORAL (kah-BURG-oh-leen)
BRAND NAME(S): Dostinex
Medication Uses | Other Uses | How To Use | Side Effects | Precautions | Drug Interactions | Overdose | Notes | Missed Dose | Storage
USES: This medication is used to treat certain hormone problems (excess prolactin). The drug is used to reduce or prevent breast milk production, except after childbirth (postpartum).
OTHER USES: This drug may also be used for Parkinson's disease, prolactin-producing tumors and to adjust various hormone levels in certain diseases (ovarian diseases).
HOW TO USE: This drug is taken by mouth twice weekly. Dosage is adjusted generally at 4 week periods based on blood tests (prolactin). Follow all instructions.
SIDE EFFECTS: Unusual weakness or fatigue, nausea or vomiting, constipation, headache, dizziness, drowsiness, tingling or numbness sensation may occur. If these persist or worsen, notify your doctor. Unlikely but report promptly: mental or mood changes. Very unlikely but report promptly: fainting, swelling of feet or ankles, breast pain, menstrual changes, vision problems. If you notice other effects not listed above, contact your doctor or pharmacist.
PRECAUTIONS: Before using this drug, tell your doctor your medical history, including: allergies (especially drug allergies), liver disease, psychiatric illness, uncontrolled high blood pressure, high blood pressure during pregnancy. Limit alcohol as it may aggravate side effects of this drug. Caution performing tasks requiring alertness, such as driving. To avoid dizziness and lightheadedness when rising from a seated or lying position, get up slowly. Tell your doctor if you are pregnant before using this medication. It is not known if this drug is excreted into breast milk. Because of the potential risk to the infant, breast-feeding while using this drug is not recommended. Consult your doctor before breast-feeding.
DRUG INTERACTIONS: Tell your doctor of all nonprescription and prescription medication you may use, especially of: blood pressure drugs, dopamine blockers (e.g., metoclopramide, antipsychotics such as chlorpromazine, haloperidol). Also report the use of drugs that cause drowsiness such as: sedatives, sleeping pills, narcotic pain relievers (e.g., codeine), anti-anxiety medications, antidepressants, muscle relaxants, anti-seizure medications, certain antihistamines (e.g., diphenhydramine). Do not start or stop any medicine without doctor or pharmacist approval.
OVERDOSE: If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly. Symptoms of overdose may include mental/mood changes, nasal congestion, fainting, lightheadedness, or irregular heartbeat .
NOTES: Do not share this medication with others.
MISSED DOSE: If you miss a dose, contact your doctor promptly to establish a new dosing schedule.
STORAGE: Store at room temperature between 68 and 77 degrees F (20-25 degrees C) away from light and moisture.
Last Editorial Review: 3/2/2005
Triple J said:
Too many ifs with this sel stuff, i mean basically over night, i went from normal to absolutly hating my life. No doubt its the sel. Ive taken letro, nolva, tren before (not methyl-DHT, but dont think its that) with no problems....so ill need another D2 agonist or levodopa or something else....maybe ill try the dostinex at say .25mg every Mon and Thurs?
macrophage69alpha
New member
doses that people will find anxiogenic with any of the compounds or combination there of will vary considerably... if you find a dosage anxiogenic then lower it.
