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PimpnAintEasy
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Here's an article from the latest Angelsfire Newsletter:
NOLVADEX EXPOSED
Nolvadex, Tamoxifen Citrate, is a drug thats technically an estrogen. Its classified as a mixed estrogen agonist/antagonist. It was developed for females with breast cancer. It works by attaching to estrogen receptors (ER) in target tissues and doing nothing. In other words, it has a benign activity in certain tissues, so when it attaches to those ER it prevents estrogen from attaching there and activating the receptor. In the early 80's, Dan Duchaine started using it on himself and others in his circle because he thought it could have the same activity in abnormal male breast tissue, he was right. Thus Nolvadex entered the bodybuilding scene. Now lets talk about the other things Nolvadex does, for one thing in many tissues it acts as an estrogen, for example, the liver, this is not good. For years "experts" in the art of performance enhancing steroid use have hypothesized that Nolvadex caused a reduction in the production of IGF-1. Well it does, just not the way a lot of people thought, in fact estrogen in high quantities causes a reduction in IGF-1, and when it attaches to ER at the liver, Nolvadex acts like an estrogen. Another common misconception is that some people think when they are using an estrogen antagonist like Nolvadex that the amount of estrogen in the body is being reduced, that's not the case, all of it is still there, wreaking havoc in other ways, like increasing the ability for the body to store macronutrients as fat and causing a reduction in IGF-1 (Nolvadex makes this event even worse). Out of all the ancillary medication out there to use as a PREVENTATIVE measure, Nolvadex is by far the worst, in addition to the things I have mentioned, Nolvadex also has many other possible side effects, most of them hematological, such as greatly increasing the possibility of venous thrombosis, and pulmonary embolism, this is not good considering that most of the steroids we use during a mass cycle increase red blood cell count, thus thickening the blood before the Nolvadex is even added. Now kept in you arsenal as a medication for gyno that has already started, Nolvadex is the best thing available to us, but if we are using anicillaries during the cycle, we will never have a reason to use it. And saying that it will benefit a cycle just aint so. Saying it should be included in every cycle is BS. There are just too many things out there that work better.
NOLVADEX EXPOSED
Nolvadex, Tamoxifen Citrate, is a drug thats technically an estrogen. Its classified as a mixed estrogen agonist/antagonist. It was developed for females with breast cancer. It works by attaching to estrogen receptors (ER) in target tissues and doing nothing. In other words, it has a benign activity in certain tissues, so when it attaches to those ER it prevents estrogen from attaching there and activating the receptor. In the early 80's, Dan Duchaine started using it on himself and others in his circle because he thought it could have the same activity in abnormal male breast tissue, he was right. Thus Nolvadex entered the bodybuilding scene. Now lets talk about the other things Nolvadex does, for one thing in many tissues it acts as an estrogen, for example, the liver, this is not good. For years "experts" in the art of performance enhancing steroid use have hypothesized that Nolvadex caused a reduction in the production of IGF-1. Well it does, just not the way a lot of people thought, in fact estrogen in high quantities causes a reduction in IGF-1, and when it attaches to ER at the liver, Nolvadex acts like an estrogen. Another common misconception is that some people think when they are using an estrogen antagonist like Nolvadex that the amount of estrogen in the body is being reduced, that's not the case, all of it is still there, wreaking havoc in other ways, like increasing the ability for the body to store macronutrients as fat and causing a reduction in IGF-1 (Nolvadex makes this event even worse). Out of all the ancillary medication out there to use as a PREVENTATIVE measure, Nolvadex is by far the worst, in addition to the things I have mentioned, Nolvadex also has many other possible side effects, most of them hematological, such as greatly increasing the possibility of venous thrombosis, and pulmonary embolism, this is not good considering that most of the steroids we use during a mass cycle increase red blood cell count, thus thickening the blood before the Nolvadex is even added. Now kept in you arsenal as a medication for gyno that has already started, Nolvadex is the best thing available to us, but if we are using anicillaries during the cycle, we will never have a reason to use it. And saying that it will benefit a cycle just aint so. Saying it should be included in every cycle is BS. There are just too many things out there that work better.
