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Anavar toxic to kidneys?
- Thread starter kingc_79
- Start date
ichabodcrane
New member
Like Buff said, just cuz it is eliminated by the kidney, doesn't mean it is toxic to it. The only concern would be accumulation of the var due to decreased renal function (decreased GFR/clearance) in general. Donor's have ~ 75-85 % of normal renal function (level of evidence B). There is also no strong evidence for the increased incidence of HTN post donation and there is also no strong evidence for increased late mortality above normal populations. There may, however be a small increase in proteinurea which seems to be NON PROGRESSIVE. So all in all, this does sound pretty good. So of course one can live perfectly fine with one kidney, but one would need to pay very careful attention to things that damage the kidney, particularly HTN, which can lead to the proteinurea I was talking about. Of course you will be monitored closely for this as well as other things. But to answer your question specifically, it should be no different than dosing any other drugs (renal dosing) in any other situation where a person has slightly diminished renal function. While I can't give you a definate answer, I think the key would lie in dosage adjustment. You would just need to be sure to dose any drug accordingly, so as not to cause accumulation of the drug which then would/could lead to toxicities. But IMO, it can be done. It is done all the time, but with careful monitoring of course. I would not attempt it alone. But I am sure you (or your practitioner) could find population paramaters which show plasma concentrations of var in normal (two kidney vs. one kidney) people to serve as guidelines to renal dosing. This could apply to any AAS or any drug for that matter. The main things you need to watch out for are drug accumulation (especially if they are renally excreted), and HTN or any condition that could exacerbate HTN. The last thing you want to do is damage your one good kidney. It is not the drug itself I am worried about, but the possible side effects of the drugs which may lead to kidney damage.
I totally applaud your actions and wish you the best of luck. Please keep us posted.
I totally applaud your actions and wish you the best of luck. Please keep us posted.
kingc_79
New member
well..surgeons met yesterday..and i can donate. I was so happy i couldnt even talk when the nurse called. I go down to san antonio on 15th to run blood 1 more time and stay till surgery on the 22nd. I'm so happy. this is my 1st surgery, but the doc said i should be able to work out again after bout 4wks
bawling: ) i know, but its worth it.
guess thats it for me with a.s. unless i convince myself that mild cycle of anavar is safe enough later on.
bawling: ) i know, but its worth it. guess thats it for me with a.s. unless i convince myself that mild cycle of anavar is safe enough later on.
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