Some more good info on Anadrol.
The use of oxymetholone should be strict and brief. While it is no doubt the strongest steroid, quantitatively, its also by far the most hazardous steroid to your health. Apart from the great risk of common steroid-related side-effects (acne vulgaris, benign prostate hypertrophy, gynocomastia and androgenetic alopecia), it also has numerous other side-effects. Most notable is oxymetholone's hepatoxicity (damaging to the liver) : Its standard 17-alpha-alkylated as with most oral steroids, resulting in an inavoidable raise in liver transaminase enzyme counts. The most frequent of the hepatoxic effects is jaundice4 (yellow coloration of the skin) due to an oxymetholone induced increase in biliburine, but others include peliosis hepatis and formation of hepatic tumors (cancer). And that's not all. There is also a number of intrinsic side-effects noted with the use of this steroid. Headaches, stomach aches, nausea, vomiting, insomnia and diarrhea are among common afflictions associated with oxymetholone use.
Other notes I should mention about this compound are that oxymetholone's androgenic qualities are not linked to a 5-alpha reduced form. As a matter of fact it shows rather poor interaction with the 5AR enzyme, making it futile to treat a possible increase in hair loss with 5-alpha reductase-blocking products such as finasteride. Its androgenic component stems from the fact that oxymetholone is very much like Dihydrotestosterone were it not for the added 2-hydroxymethylene group. Since this group can be metabolically removed, that would leave methyl-DHT. A compound with a weaker affinity for the androgen receptor than straight DHT, but more active and with less affinity for the DHT-reducing enzyme 3beta hydroxysteroid dehydrogenase. Ultimately resulting in much stronger, instead of weaker androgenic effects than compounds that are actively 5-alpha reduced. This evens out largely, because the distribution is even across the body, where 5-alpha-reduction usually concentrates more potent androgenic forms in androgen responsive tissue such as skin and scalp.
The effect on the blood pressure is rather drastic, so its recommend that you use a anti-hypertensive drug in conjunction, especially if you already have a fairly high blood pressure. Here too the care and control of a physician is advised. Because of the HPTA (hypothalamic-pituitary-testicular axis) suppressive nature, the use of Clomid or Nolvadex and HCG is advised as well towards the end of your oxymetholone use. Lastly, oxymetholone also has an ill effect on the glucose tolerance5, causing borderline diabetic situations. Something to be weary of if you yourself have been diagnosed with similar problems already.