An interesting conversation with my Endocrinologist

[Ffactor]

He said 200 mg of Test Enanthate every other week is enough to cause negative feedback and suppress endogenous testosterone production.

 

[swordfish151]

He said 200 mg of Test Enanthate every other week is enough to cause negative feedback and suppress endogenous testosterone production.

anyone have knowledge on this? and is it just Enanthate? or test period?

 

[Ffactor]

Personally, I don't think there is any medical evidence to substantiate that, it's all theory.

 

[|3ossman]

Why are you suprised by this, of course it will supress your natural test. production. 100mg of test a week will shut you down.

 

[sherpa1]

200 mg of Test Enanthate "or any other long acting test" every other week IS enough to cause suppress endogenous testosterone production while your taking it every other week. That will go away with time / pct depending on how long you took 200mg every other week.

From what I have read, the average guy only makes around 100mg a week of test. So if you are getting that 100mg a week of test elsewhere, it would be enough to suppress test production. I dont know what he means about the negative feedback.

 

[Makavelli]

Yeah it would. That's roughly what your body produces naturally.

 

[Alpine`]

I dont see why this is suprising? Even a small amount of Var can be suppressive...
The bodies Endocrine System is a complex, delicate & finely tuned system. Toying with it even slightly brings imbalances.

 

[StereOMaN]

I agree with Bossman. The body only produces about 100mg of test a week that amount is regulated by that feedback loop, that means if your body only wants to produce 100 under normal circumstances if 102mg were present they would be inhibited by the feedback mechanism until the 100 mg was maintained. Homeostasis. ergo 200mg of Test anything eow reaches ~100mg per week, you don't need anymore so your nuts wont make any more - inhibition, this mechanism is exactly what Negative Feedback is. He just tried to word it that way to scare you. Doctors love their nomenclature. If you were planning on doing 200mg of Test E eow, please skip it and send me the money instead. You would just be replacing and maintaining the normal amount of test in your body while shutting down your nuts. You will not be any more anabolic. Unless you were just using it in horomone replacement therapy then you are fine for that purpose.

 

[Ffactor]

Only way to tell is checking LH/FSH mid cycle. He also doesn't recommend PCT, he says given time it will reverse itself. I say bullshit, HCG should jump start my pituatary if its asleep. I'm not willing to wait for a year for my things to turn to normal.

 

[Madcow2]

Natural test production varies for each individual but I don't ever believe I've seen the average quoted at or near even 10mg daily (7 I believe was it but it's been so long). So for the sake of argument we assume everyone here is superhuman and gets 10mg a day that's 70mg per week. If you take 200mg weekly (nearly 3x our very generous estimate and almost 4x what I recall being the right number) you are already way over. Make it a long ester not only do you have the 200mg but you get weekly layers as the half-lives don't completely delete the test so hit a spreadsheet and do the math but no matter what you come up with you are suppressed.

EDit: bad math above

 

[|3ossman]

Only way to tell is checking LH/FSH mid cycle. He also doesn't recommend PCT, he says given time it will reverse itself. I say bullshit, HCG should jump start my pituatary if its asleep. I'm not willing to wait for a year for my things to turn to normal.

Smart endo some doctors are so stupid, it never ceases to amaze me. What the fuck is this guy thinking, please somebody tell me

 

[Judo Tom]

it will most likely suppress you at those levels

 

[Anthony Starks]

He also doesn't recommend PCT, he says given time it will reverse itself. I say bullshit, HCG should jump start my pituatary if its asleep. I'm not willing to wait for a year for my things to turn to normal.

Your pituary gland is constantly working, it never is "asleep" and can't be "jump started". It can, however, be supressed, in which case adding more suppressive hormones (HCG) is not the answer. Listen to your doc, run a nolvadex PCT and then take some time off

 

[LoneTree]

He said 200 mg of Test Enanthate every other week is enough to cause negative feedback and suppress endogenous testosterone production.

I have enough knowledge of endocrinology to have an opinion.
Your endocrilogist is right. Any exogenous administration that causes your test levels to be higher than normal would shut down endogenous production.
But look at the practical effect:
It only means that you have to do PCT.
Your endogenous production is not high enough to make much difference in your gains because you are taking 'super-physiological' dose.

 

[Ffactor]

Whats the best PCT in this case? As you guys know my tets levels were close to 0 ng/l after a four week stint with M1-T. No sex drive at all. Started taking Test Enan to improve sex drive, I've been on a low dose of test on and off to counter low natural test levels for years.

 

[cboogsrun]

Why are you suprised by this, of course it will supress your natural test. production. 100mg of test a week will shut you down.

I would agree with you. I believe the body make anywhere from 6mg-9mg of test a day. So thats 42-63mg a week. so 160% to 200% more in your body. Chances are it'll shut down. Does anyone know the half-life of Natural Test?

Boogs

 

[Ffactor]

Just got off the phone with my endo. Blood test results are back and he was flippin out because my test levels were >1,600 ng/l. He said it could cause sudden death. I told him to relax, 400 mg/ml of test ain't gonna kill me.

 

[PolfaJelfa]

Of course it will shut you down. Its a no brainer.

 

[doublebicep]

Of course it will shut you down. Its a no brainer.

Seems obvious to me - shutdown.

 

[view]

Of course it will shut you down. Its a no brainer.

 

[Ffactor]

Shut me down, yes, kill me, no.

 

[dsh89]

Negative feedback is how most hormones in the body work. It is all about chemoreceptors and stimulation. When the body detects there is not enough hormone, it sends signals to make or release more. Whne levels rise, it sends signals to withold or stop production. So yeah, if you have more than your normal amount of test, you will stop producing it.

 

[Slydog]

Shut me down, yes, kill me, no.

Kill you, what kind of Jackass MD/Endo is this. It pisses me off to hear someone who is supposedly educated in this arena say something so.... stupid (400mg a week of test could cause sudden death) OK and Oh yeah I forgot that I could go blind from jerking off.

 

[_Yossarian_]

Of course it will shut you down. Its a no brainer.

.

 

[|3ossman]

Just got off the phone with my endo. Blood test results are back and he was flippin out because my test levels were >1,600 ng/l. He said it could cause sudden death. I told him to relax, 400 mg/ml of test ain't gonna kill me.

LOL see what i mean, thanks for making my point. some of them have NO clue

 

[LVTitan]

Only way to tell is checking LH/FSH mid cycle. He also doesn't recommend PCT, he says given time it will reverse itself. I say bullshit, HCG should jump start my pituatary if its asleep. I'm not willing to wait for a year for my things to turn to normal.

i've always recovered quickly from test cycles w/out any pct , never had a problem.
i'm currently only taking 125mg/week of test e as a maintenance dose during my primo cycle. i'll be adding eq to the mix in about a week, i may even end up dropping the test, not sure yet.

and to answer the original question< of course exogenous test will shut down your natty production, there is definitely no suprise there, why would you think otherwise ?

 

[Ffactor]

Well actually the focus has now shifted to KILLING me. Just wanna let you know what the endo said.