AG-GUYS Best for Gyno???

[Mr.X]

Mr X, could you elaborate on the benefits of using nolvadex and femera together? Is the nolva for lipid profile issues, or is there a synergystic effect i'm not grasping? Thanks.

This thread is about gynecomastia, not lipid profiles. You missed the point a bit bro. The nolvadex + femara (letrozole) combination is very potent for getting rid of gyno/gyno symptoms.

 

[Mr.X]

J Steroid Biochem Mol Biol. 2001 Dec;79(1-5):27-34. Aromatase overexpression transgenic mice model: cell type specific expression and use of letrozole to abrogate mammary hyperplasia without affecting normal physiology.

Mandava U, Kirma N, Tekmal RR.

Department of Gynecology and Obstetrics, Emory University, 4217 Woodruff Memorial Building, 1639 Pierce Drive, Atlanta, GA 30322-4710, USA.

Our recent studies have shown that overexpression of aromatase results in increased tissue estrogenic activity and induction of hyperplastic and dysplastic lesions in female mammary glands and gynecomastia and testicular cancer in male aromatase transgenic mice. Both aromatase mRNA and protein are overexpressed in transgenic mammary glands and its expression is not limited to epithelial cells. However, it is more in epithelial than in stromal cells.Our results also indicate aromatase overexpression-induced changes in mammary glands can be abrogated [destroyed] with very low concentrations of the aromatase inhibitor, letrozole. Low concentration of letrozole had no effect on normal physiology as indicated by no significant change in the circulating levels of estradiol and follicle stimulating hormone as well as no change in estrogen responsive genes such as the progesterone receptor and lactoferrin in the uterine tissue. These observations indicate that the expression of aromatase in both epithelial and stromal cells can influence the complex interactions of biochemical pathways leading to mammary carcinogenesis and that the aromatase inhibitor, letrozole can be used as chemopreventive agents without affecting normal physiology.

 

[RaoulDuke..]

This thread is about gynecomastia, not lipid profiles. You missed the point a bit bro. The nolvadex + femara (letrozole) combination is very potent for getting rid of gyno/gyno symptoms.

i'm right with you on this thread being about gyno. i was wondering if the addition of nolvadex along with the femera was to improve lipid profiles caused by the femera. i have read nolva has a positive effect in that respect. if i remember correctly some members have added low dose nolva along w/ arimidex for such issues. am i misunderstood?

What i'm not understanding is the benefit of using a serm along w/ an AI to reduce gyno. i guess my logic is that if aromatization is inhibited, whats the use in blocking estrogen from breast tissue receptors? i'm obviously confused about something here, thanks for the help.

 

[Mr.X]

i'm right with you on this thread being about gyno. i was wondering if the addition of nolvadex along with the femera was to improve lipid profiles caused by the femera. i have read nolva has a positive effect in that respect. if i remember correctly some members have added low dose nolva along w/ arimidex for such issues. am i misunderstood?

What i'm not understanding is the benefit of using a serm along w/ an AI to reduce gyno. i guess my logic is that if aromatization is inhibited, whats the use in blocking estrogen from breast tissue receptors? i'm obviously confused about something here, thanks for the help.

I answered your question here
http://www.elitefitness.com/forum/showthread.php?t=460900

 

[RaoulDuke..]

i know, i posed this particular question before i had started that thread. just ordered some ag letro...from what i hear it's top notch...we'll see how it goes, thanks for the help

 

[Mr.X]

i know, i posed this particular question before i had started that thread. just ordered some ag letro...from what i hear it's top notch...we'll see how it goes, thanks for the help

good man, ag is top notch bro.

how far in is your gyno?

 

[RaoulDuke..]

good man, ag is top notch bro.

how far in is your gyno?

well, it's sort of hard to say. i had small glandular in the left ever since i was 15, and only "puffiness" in the right up until i did my first cycle last spring/early summer. i did 350mg test/wk, .5mg arimidex ED, 15 mg nolva ED for 12 weeks. believe it or not the gyno/puffiness disappeared throughout the duration and up until about a month after my cycle. i experienced no tingling or pain, but the gyno seemed to reappear. now it's a bit worse than it was before my cycle, but i'm gonna run 1.25mg AG GUYS letro and see what happens. i'll post an update with my results.

 

[Mr.X]

well, it's sort of hard to say. i had small glandular in the left ever since i was 15, and only "puffiness" in the right up until i did my first cycle last spring/early summer. i did 350mg test/wk, .5mg arimidex ED, 15 mg nolva ED for 12 weeks. believe it or not the gyno/puffiness disappeared throughout the duration and up until about a month after my cycle. i experienced no tingling or pain, but the gyno seemed to reappear. now it's a bit worse than it was before my cycle, but i'm gonna run 1.25mg AG GUYS letro and see what happens. i'll post an update with my results.

Letro + nolvadex is what I suggested here, not letro alone. I'm going to assume you're running the combo, right?

 

[RaoulDuke..]

Letro + nolvadex is what I suggested here, not letro alone. I'm going to assume you're running the combo, right?

I had planned on starting w/ letro alone and add nolvadex if i get no/little results. i have both on hand, but would rather save the nolva if i can get away w/ it. bad idea? do i need the nolva to act directly on breast receptors? has anyone you know of had success w/ letro alone? much appreciated.

 

[Mr.X]

I had planned on starting w/ letro alone and add nolvadex if i get no/little results. i have both on hand, but would rather save the nolva if i can get away w/ it. bad idea? do i need the nolva to act directly on breast receptors? has anyone you know of had success w/ letro alone? much appreciated.

Saving something can give you problems down the road. The longer you have the gyno, the harder it is to get rid of. Think of it this way, your 'savings' can amount to a $5000 gyno surgery.