I meant if you have gyno already and you are mid-cycle. If you are mid-cycle haven't been using arimidex, you will already have very high estrogen levels. Arimidex doesn't reduce already high estrogen levels, it just prevents new estrogen from forming, hence the need to start it before your cycle (before the estrogen forms in the first place). If you already have gyno and are just about to start a cycle, running arimidex before and through your cycle *should* ensure estrogen levels stay low and thus avoid the gyno from increasing. But there are no guarantees, so in that case I would play it safe and also use nolva.