Addicted to GHB

[FullCircle]

Fonz, I don't see the need to be so defensive. You are acting (note I said "acting") like an addict with your denile and defensiveness.

A case of withdrawal from the GHB precursors gamma-butyrolactone and 1,4-butanediol.

Schneir AB, Ly BT, Clark RF.

Division of Medical Toxicology, Department of Emergency Medicine, UCSD Medical Center, California Poison Control System-San Diego Division, 200 West Arbor Drive, San Diego, CA 92103-8925, USA.

We describe a case of withdrawal from the gamma hydroxybutyric acid (GHB) precursors gamma butyrolactone and 1,4-butanediol. Symptoms included visual hallucinations, tachycardia, tremor, nystagmus, and diaphoresis. Administration of benzodiazepines and phenobarbital successfully treated the withdrawal symptoms. As predicted from the metabolism of gamma butyrolactone and 1,4-butanediol to GHB, the symptoms were nearly identical to those reported from GHB withdrawal. Because GHB is now illegal in the United States, individuals have begun abusing the legal and easier to acquire GHB precursors. More frequent cases of both abuse and withdrawal from these GHB precursors can be expected.

Gamma-hydroxybutyrate withdrawal syndrome.

Dyer JE, Roth B, Hyma BA.

California Poison Control System, San Francisco Division, San Francisco General Hospital, CA 94110, USA. [email protected]

STUDY OBJECTIVE: Gamma-hydroxybutyrate (GHB) withdrawal syndrome is increasingly encountered in emergency departments among patients presenting for health care after discontinuing frequent GHB use. This report describes the characteristics, course, and symptoms of this syndrome. METHODS: A retrospective review of poison center records identified 7 consecutive cases in which patients reporting excessive GHB use were admitted for symptoms consistent with a sedative withdrawal syndrome. One additional case identified by a medical examiner was brought to our attention. These medical records were reviewed extracting demographic information, reason for presentation and use, concurrent drug use, toxicology screenings, and the onset and duration of clinical signs and symptoms. RESULTS: Eight patients had a prolonged withdrawal course after discontinuing chronic use of GHB. All patients in this series were psychotic and severely agitated, requiring physical restraint and sedation. Cardiovascular effects included mild tachycardia and hypertension. Neurologic effects of prolonged delirium with auditory and visual hallucinations became episodic as the syndrome waned. Diaphoresis, nausea, and vomiting occurred less frequently. The onset of withdrawal symptoms in these patients was rapid (1 to 6 hours after the last dose) and symptoms were prolonged (5 to 15 days). One death occurred on hospital day 13 as withdrawal symptoms were resolving. CONCLUSION: In our patients, severe GHB dependence followed frequent ingestion every 1 to 3 hours around-the-clock. The withdrawal syndrome was accompanied initially by symptoms of anxiety, insomnia, and tremor that developed soon after GHB discontinuation. These initial symptoms may progress to severe delirium with autonomic instability.

Just a couple more... There is one I am aware of that is an actual in house study that was done in the early 80's, but I can't seem to find it. I'll keep looking.

Anyway, listen guys, I find GHB as benefitial and enjoyable as anyone, trust me on that. There is a reason I feel GHB to cause physical dependency that is beyond 3rd person anecdotes. Myself and at least three others suffered withdrawls from it a couple years ago after 25g+ daily usage. Although mine were minor compared to some of the above listed (anxiety, depression, insomnia, lethargy...likely a result of the insomnia) they were without a doubt present. Lasted about a month till all symptoms subsided, most lingering being the anxiety, and the shortest lived was insomnia lasting about a week. If used properly its a safe and useful compound, but it does have drawbacks if abused. There is no argument when it comes to comparing toxicity and addictive potential...alcohol kicks GHB's ass.

GHB is our friend, just don't piss him off and use him too much.

-FC

 

[Wombat]

Quote by Fonz in the club board

I've got a 500ml bottle of GHB for my 7-day stay there. I'm going to go through the ENTIRE bottle this year..............muhaha

Just thinking about the party gets me wired.
I'm NOT sleeping for the ENTIRE week.(Yeah right....LOL

END Quote---

Does this sound like a guy who takes it just to sleep?????

 

[Fonz]

Quote by Fonz in the club board

I've got a 500ml bottle of GHB for my 7-day stay there. I'm going to go through the ENTIRE bottle this year..............muhaha

Just thinking about the party gets me wired.
I'm NOT sleeping for the ENTIRE week.(Yeah right....LOL

END Quote---

Does this sound like a guy who takes it just to sleep?????

Wombat, you are SO TAKING my post out of context.

I WILL BE IN IBIZA!!!!!

In IBIZA you PARTY ALL-DAY.

I'd rather do GHB than weed, alcohol, X,K, LSD, speed, etc.. etc..

I did this last year and the year before that and had NO PROBLEMS.

I use high doses only for one week THE ENTIRE YEAR and I'm
addicted to it.......LOL

I'm sorry but taking GHB in high doses is FAR SAFER than
combining 3-4 party drugs all at once+copious amounts
of alcohol.

Besides, I normally ony go through about 250-300ml at the
most in those 7 days. Thats 35-40ml's/day.

I also go clubbing for about 14 hours/day.

High amount excercise=High GHB excretion rate

Not to mention my tolerance IS MUCH HIGHER than
a normal persons.

The only problem I get at high doses is I lose my
apetite. Thats about it.

Once out of ibiza I just go back to my normal routine.

So, nice try.

Godspeed

 

[FrankRizzo]

It's Machiavelli

 

[Wombat]

FONZ ---I agree IBIZA is all about partying and I to use G from time to time but you are stating that you use it just to sleep. No where is this thread have you said that you use it to party. But ONLY to sleep ---that is why I put your quote up there.

 

[ragin']

good insight from everyone. could anyone post an article or some written facts to supports thier opinions?

 

[NCLifter]

GHB is a great drug/supplement

You need to know how to use it correctly. Get sodium based G from a reliable source. Try it out at home and then take a few caps before you go out. Drink a few beers and you will feel relaxed and happy. Do not start taking caps after your shot of jager or you will end up in the ER. Take a few caps, get relaxed then drink a few miller lights. Leave the G at home. Dont fucking abuse it and start taking it every day or you are in for serious trouble. I took it all day long for a year and it totally killed my sex drive, I felt akward without it and when I did take caps, I felt horrible about myself becaue I knew I needed help. Stay away from potassium based G that will land you in the ER quick. GHB is an excellent drug for athletes. Respect it and dont abuse it.

 

[Andy13]

Here's my $.02 on the topic..

I think "addiction" is very, very psychological. I've done GHB for two years straight.. Came off cold turkey with no problems..

I've even used the infamous 'bain every day for two weeks straight.. Came off cold turkey-- no problems.

I can't help that weak willed and un-diciplined individuals get addicted (physiologically of psycholgically, whatever) and then try and blame the drug for their weakness.

I am however addicted to nasal spray.. go figure... But I don't "see vampires " or shit like that when I don't use it.. I juse cannot breathe as well.

Andy

 

[jakethemus]

I don't think addiction is purely psychological at all.
That is Bullshit!
Some of us have a genetic predispition (sp?) to addiction.
All this weak willed, un disciplined talk really fucking winds me up.

Maybe for a lot of people GHB isn't addictive at all, but for a few people including myself it is very addictive and the withdrawls are no joke.

Anyway GHB is crap if you ask me, smoke a joint if you need to get high or get to sleep, its more fun and less likely to fuck you up.

Just my opinions on this.

 

[1Mistake]

WTF???? GHB is OTC in Europe and used to treat alcohol and H addictions...for like 20 yrs now....

J