unleashed from protein factory. Whats in it,what it can do, why to take it on,off,or,pct
stinging nettle root. Lets first take a look at just one part of the nettle root. That part you are talking about. lowering the shbg. Now it has other uses and we will get into that but this is what you are asking to be addressed first.
3,4-Divanillyltetrahydrofuran this is part of the nettle root. Feel free to look it up.but wika makes mention of it here
Stinging nettle - Wikipedia, the free encyclopedia along with a lot of its other components and uses.
3,4-Divanillyltetrahydrofuran
(Planta Med. 1997 Dec;63(6):529-32.
Lignans from the roots of Urtica dioica and their metabolites bind to human sex hormone binding globulin (SHBG).
Schöttner M, Gansser D, Spiteller G.
Lehrstuhl Organische Chemie I, Universität Bayreuth, Germany.
Polar extracts of the stinging nettle (Urtica dioica L.) roots contain the ligans (+)-neoolivil, (-)-secoisolariciresinol, dehydrodiconiferyl alcohol, isolariciresinol, pinoresinol, and 3,4-divanillyltetrahydrofuran. These compounds were either isolated from Urtica roots, or obtained semisynthetically. Their affinity to human sex hormone binding globulin (SHBG) was tested in an in vitro assay. In addition, the main intestinal transformation products of plant lignans in humans, enterodiol and enterolactone, together with enterofuran were checked for their activity. All lignans except (-)-pinoresinol developed a binding affinity to SHBG in the in vitro assay. The affinity of (-)-3,4-divanillyltetrahydrofuran was outstandingly high. These findings are discussed with respect to potential beneficial effects of plant lignans on benign prostatic hyperplasia (BPH).
PMID: 9434605 )
Le Magazine February 1999: Bph The Other Side Of The Coin
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Read this whole dame thing if you like. I did and because I enjoy this shit but you would be best to just skip right down to this part.
(Accordingly, these researchers studied an agent thought to inhibit the binding of SHBG to the prostate cell membrane, an extract of the root of the stinging nettle plant, Urtica dioica. In a paper published in 1995 in Planta Medica, they demonstrated that nettle root does indeed inhibit the binding of SHBG to the cell membrane.
In a subsequent series of articles, German researchers have identified a constituent of nettle root known as (-)-3,4-divanillyltetrahydrofuran whose very high binding affinity to SHBG they describe as "remarkable." These researchers suggest that the beneficial effects of plant lignans (such as found in flaxseed oil) on hormone-dependent cancers may be linked to their binding affinity to SHBG. The most potent known lignans in this respect are constituents of nettle root.
Studies show that the ethanolic extract of nettle root is not in inhibiting SHBG binding, while the aqueous and methanolic extracts are.
In addition to inhibiting SHBG binding, at least six constituents of nettle root inhibit aromatase, reducing conversion of androgens to estrogens. Combining nettle root with pygeum results in a stronger, synergistic inhibition. The studies on aromatase inhibition by nettle root used methanolic extracts.) its in the middle of the article and yes the article has copies of the studies don as well.
OK but that is just one part of the nettle root and just a little peace of the product. Lets keep going. you can reed more about the nettle root all across the net. you will see it was a cover story on life extentions mag in 2004 and has been talked about all over for years now
Le Magazine, February 2004 - Cover Story: Testosterone Attacked By The Media
more reads.
Database entry for Nettle - Nettles - Urtica dioica - Nettles - Urtica dioica
Stinging Nettle by Ray Sahelian, M.D., benefit for allergy, prostate
Stinging Nettle Root - Herbs & Supplements - Drug Library - DrugDigest
apotheblogary: Nettle root tincture
and 100,000 other sites studies blah blah blah...
other studies and publications to check out
See:
Extraction and purification of a substance with luteinizing hormone releasing activity from the leaves of Avena sativa. Fukushima M, Watanabe S, Kushima K.
Schottner M, Gansser D, Spiteller G. Lignans from the roots of Urtica dioica and their metabolites bind to human sex hormone binding globulin (SHBG). Planta Med 1997 Dec;63(6):529-32.
Hryb DJ, Khan MS, Romas NA, Rosner W. The effect of extracts of the roots of the stinging nettle (Urtica dioica) on the interaction of SHBG with its receptor on human prostatic membranes. Planta Med 1995 Feb;61(1):31-2.
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Avena Sativa... As far as I can see the only study/reputable source I could find about Avena Sativa and its effects on ether raising free test lowring shbg was that the Institute for Advanced Study of Human Sexuality in San Francisco suggests that Avena Sativa does release Testosterone from its binding proteins. of course again there is 50000 different sites and shit claiming it and putting out some info on it but not much.... I believe this is a subject that will get researched more in the future
Non the less lets take a look at what sites across the net have to say.
Avena Sativa=Avenacosides A&B a fuck do a google search yourself I am slowing down now lololol... Seems to be some good shit...
Muira-Puama . There has been several studies don on its effects on Prolactin and it has been shown to lower Prolactin. This is prob the reason why its been slung all over the industry as a (sex booster)... It also has a effect on blood flow. Many people who take it report a pump like feeling... I myself have used it in high doses just to test it out for products I plan to make later down the road... Its hit mor miss with a lot more hit on this ingredient. I would say a good 80% of the people who use just this in pill form alon have reported a increasing sex drive. So much so that almost every otc libdo increasing product has this in it these days.. Potency and purity makes all the difference in the world IMO so some product clam to have lots when they really have shit. I would only get this from places you trust.. As I stated I have looked into it a lot and its not cheap. So companies will most deff try to lie about how much there product has of this ingredient.
You can research Muira-Puama on google and find all kinds of good shit.
A fuck I am spending way to much time doing this one... There is like 5 more ingredents in the product and I am sure I can find a lot of good reasons why they work,why they are in the product and all that shit....bottom line though..
1. protein factor has been a great sponsor. Many people love and trust them not only on ef but across the net.
2. Nelson himself has been a great bro to have on ef. He is smart,fun, and most of all he helps out big time.
3. I have used unleashed myself and I liked the (increase in sex drive it gave me) this is the only reason I used the product. I only used it an hour before pounding my wifes love cave, and for that reason it worked great.
4. thousands of others have used the product and other products from protein factory and every one has been pretty damn happy with there results.
5... I may come back to this post and thread and spend a more time on it but for now. Unleashed is good shit.
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