1. You shouldnt ever up your dose, your first time using it till after the 3rd day. Meaning if you are taking 200 dont up it till DAY 4!.
2. I have not tried crystal before but from what I have read, it is roughly = to 2 times that much in powder.
So in essence your friend started out on a 400 dose of powder(too high for 1st time), then upped it to 800mg(way too high 4 1st time especially since he is only 180lbs) powder before the 400mg dose had enough time to take full effect in the body. IMHO you both should have done more research before you tried but now I am happy that you didnt get hurt and also happy that your friend didnt die. I hope he recovers fully. If you know what you are doing with dnp and take your time with it I believe it is safe as many other things people take like diuretics and shit like that. There is no need to hurry to up the dose with DNP, you have alot of time to lose weight but you only have one life. BE SMART and God Bless
Chuck