Most anti-depresants can be tough on the liver, they also take 4-8 weeks to kick in, with that in mind I personally feel your best bet is to prepare for post cycle recovery, try hcg the last couple weeks of cycle. Add anastrozole/letrozole to post cycle recovery, get some viagra/cialis for labido etc. I think anti-depresants definatly have thier place but I dont think post cycle is it.