If you're on a cycle you could take 2 grams of ibuprofen a day and still make gains. In theory on paper NSAIDS inhibit muscle gains, and if you're taking hi doses every day, not eating, and not on cycle, you might start to lose muscle mass. But all this crap about NSAIDS being poison to bodybuilders is garbage. It's also a way for sources to push their "pain meds".