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Someone please define what you mean by 'derived'!
Which one is harsher on Hair? Sus or Primo?
- Thread starter mrt
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This is taken from http://www.mesorx.com/articles/roberts/000124.htm
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DHT derivatives
I have read numerous articles which stated that Primobolan Depot and Winstrol were derivatives of DHT and are particularly bad for hair loss. Is this true? Are they derived from DHT?
In medicinal chemistry, one starts with a "lead compound" that has some activity you are interested in: for example, it acts as an androgen. Compounds which you make from that compound, but which now are different because of what you have done to it, are called derivatives of that compound. A derivative will generally differ from the parent compound in its properties.
In other words, what I am saying is that whether a steroid is a "derivative" of DHT is purely a question of historical interest: it has nothing to do with how the compound acts in the body.
Incidentally, Primobolan and Winstrol could also be called a testosterone derivatives, or androstenedione derivatives, or DHEA derivatives even. So you can see the whole thing is a moot point and anyone who bases arguments on it is just playing tricks with words.
In fact Primobolan and Winstrol act differently from DHT in that, unlike DHT, they are not converted to androstanediol. They are comparable in effect on the hair to anabolically-equivalent doses of any other synthetic except nandrolone.
Would 200mg of Primobolan Depot be harsher on scalp hair than 200mg of testosterone enanthate?
Nope. Easier.
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DHT derivatives
I have read numerous articles which stated that Primobolan Depot and Winstrol were derivatives of DHT and are particularly bad for hair loss. Is this true? Are they derived from DHT?
In medicinal chemistry, one starts with a "lead compound" that has some activity you are interested in: for example, it acts as an androgen. Compounds which you make from that compound, but which now are different because of what you have done to it, are called derivatives of that compound. A derivative will generally differ from the parent compound in its properties.
In other words, what I am saying is that whether a steroid is a "derivative" of DHT is purely a question of historical interest: it has nothing to do with how the compound acts in the body.
Incidentally, Primobolan and Winstrol could also be called a testosterone derivatives, or androstenedione derivatives, or DHEA derivatives even. So you can see the whole thing is a moot point and anyone who bases arguments on it is just playing tricks with words.
In fact Primobolan and Winstrol act differently from DHT in that, unlike DHT, they are not converted to androstanediol. They are comparable in effect on the hair to anabolically-equivalent doses of any other synthetic except nandrolone.
Would 200mg of Primobolan Depot be harsher on scalp hair than 200mg of testosterone enanthate?
Nope. Easier.
panerai said:
Hey thanks for correcting me, panerai. I have always read that primo is THE hardest on the hair. Since the whole hair issue has never concerned me, I just let it go at that. Also, since primo does not interest me that much, I have not done more than cursory research into it.
Good info.
badazzwhitedude
New member
That is interesting info panerai. It just seems that if you used anything that was derived from DHT, it could possibly accelerate hair loss. I do realize that every AS is related to testosterone, but at least if it were Test itself (has not yet converted to DHT and only some of it will convert), or a 19-nor drug (Deca or Fina, which some of that would convert to the weaker nor-DHT), it would be less likely to lose hair than if you used an AS that was already derived from DHT. But, then, like you said, once it has been changed from DHT, it is just a deriative and may act differently.
I have used some Primo before, however, and I didn't seem to have any problems. I have never used Winny, but I have read that it is a very potent androgen stimulator, including to those in the scalp, possibly causing a little hair loss. You just have to try it for yourself.
I have used some Primo before, however, and I didn't seem to have any problems. I have never used Winny, but I have read that it is a very potent androgen stimulator, including to those in the scalp, possibly causing a little hair loss. You just have to try it for yourself.
BadAzz, in my opinion, all this info is for guys who are prone to MPB. For anyone else, it is kind of important, but not an immediate concern.
As one of the MPB club members, I found out on my personal experience, that Test by itself is no bueno! with Finasteride/Saw Palmetto/Nizoral shampoo/Xandrox is ok!
I don't touch Deca or Tren anymore! Loosing hair, but not that bad on dbol, if I multiply dose of Saw Palmetto by 4!
LOL
As one of the MPB club members, I found out on my personal experience, that Test by itself is no bueno! with Finasteride/Saw Palmetto/Nizoral shampoo/Xandrox is ok!
I don't touch Deca or Tren anymore! Loosing hair, but not that bad on dbol, if I multiply dose of Saw Palmetto by 4!
LOLAnabolicum Mister
New member
Thanks for the post Panerai, that was exactly my point. Winstrol is can also be 'derived' from anadrol but how similar are they pharmacologically? Not very!
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