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Spartacus
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yohimbe
well gary i have great respect for you and most of your inof,but you have it wrong regarding yohimbe's desire enhancing effects......."Enter yohimbine.
Chemically, yohimbine is classified as an alpha-2 adrenergic receptor blocker. Alpha-2 adrenergic receptors are located primarily in the abdominal and pelvic area, including the primary sex organs.
As an receptor blocker, yohimbine is, in a way, an anti-hormone. But in another way, it is similar to cocaine and amphetamine in causing mental agility and arousal.
Why?
The only explanation that seems to make sense is that by interfering with the docking of epinephrine (adrenaline) in the abdominal and pelvic tissue, or by even replacing it from alpha-2 receptors to which it normally is bound, yohimbine causes an increase of freely circulating epinephrine / adrenaline.
The freely circulating additional epinephrine (adrenaline) as a hormone exerts the typical adrenergic effect on the heart, leading to an increased heart rate (tachycardia, palpitations) which will always occur with a sufficiently high dosage of yohimbine. But because epinephrine is not just a hormone but also a neurotransmitter, it also effects the central nervous system in a manner which actually is quite similar to cocaine or amphetamine, with increased alertness, mental agitation, and proneness to arousal, sexual and otherwise.
Yohimbine is unique in that it has a dual aphrodisiac function: it improves sexual function by displacing hormonal epinephrine from alpha-2 adrenergic receptors in the pelvic area, and it increases proneness to arousal through supplying the epinephrine from the alpha-2 adrenergic receptors to the central nervous system (the brain), where it is active as a neurotransmitter.
As a pro-sexual drug, yohimbine has a definite edge over cocaine, amphetamine, and methamphetamine. The three street drugs may have the effect of causing sexual arousal, but at the same time interfere negatively with sexual function.
This is the case because hormonal epinephrine not only has the function to increase heart rate and blood pressure in order to make the body ready for fight or flight, but also to shut down functions that are not essential for fighting or fleeing. Blood is drawn from the digestive tract while bowel movement may be hastened to rid the body of weight.
Vasodilatation in the genital tract is made impossible. An erection during a fight would be an unwelcome obstacle, and a highly vulnerable target on top of that. This is why the increased catecholamine levels effected by cocaine, amphetamine, and methamphetamine all lead to a strong shrinkage of the male genitals. Therefore, what one gets from cocaine and amphetamines is a plus in desire and a minus in capability… an odd combination indeed.
Yohimbine, on the other hand, does not elevate epinephrine effects throughout the body. Yohimbine effects a minus of epinephrine in the abdominal and genital areas where alpha-2 adrenergic receptors prevail, and a plus of epinephrine in the central nervous system and other, mostly upper parts, of the human body.
In order to understand why the interference with alpha-2 adrenergic receptors works to facilitate erections, one has to know that the normal, flaccid genital state is, in the first place, only caused by hormonal epinephrine (adrenaline) being almost permanently docked to alpha-2 adrenergic receptors. To achieve an erection normally, nerve impulses will have to initiate a physiological process by which epinephrine (adrenaline) is removed from alpha-2 adrenergic receptors.
The same effect can be reached by ingesting some 5 to 50 milligram of yohimbine. "..........."
Yohimbe and yohimbine will make those who have ingested it easier to stimulate sexually. Yohimbe works mentally and physically towards this end, with both aspects strongly interacting. Men who normally have problems having an erection will feel a mental stimulation from the fact that a hard-on comes easy.
Yohimbe definitely increases erectile rigidity, and may increase erectile capacity. Yohimbe will definitely make orgasms more powerful. It will do this by postponing the point of ejaculation, and by making the orgiastic release more strongly felt. On the route to the orgiastic release, there will be a greatly accelerated heartbeat, caused by mental stimulation rather than physical effort"
well gary i have great respect for you and most of your inof,but you have it wrong regarding yohimbe's desire enhancing effects......."Enter yohimbine.
Chemically, yohimbine is classified as an alpha-2 adrenergic receptor blocker. Alpha-2 adrenergic receptors are located primarily in the abdominal and pelvic area, including the primary sex organs.
As an receptor blocker, yohimbine is, in a way, an anti-hormone. But in another way, it is similar to cocaine and amphetamine in causing mental agility and arousal.
Why?
The only explanation that seems to make sense is that by interfering with the docking of epinephrine (adrenaline) in the abdominal and pelvic tissue, or by even replacing it from alpha-2 receptors to which it normally is bound, yohimbine causes an increase of freely circulating epinephrine / adrenaline.
The freely circulating additional epinephrine (adrenaline) as a hormone exerts the typical adrenergic effect on the heart, leading to an increased heart rate (tachycardia, palpitations) which will always occur with a sufficiently high dosage of yohimbine. But because epinephrine is not just a hormone but also a neurotransmitter, it also effects the central nervous system in a manner which actually is quite similar to cocaine or amphetamine, with increased alertness, mental agitation, and proneness to arousal, sexual and otherwise.
Yohimbine is unique in that it has a dual aphrodisiac function: it improves sexual function by displacing hormonal epinephrine from alpha-2 adrenergic receptors in the pelvic area, and it increases proneness to arousal through supplying the epinephrine from the alpha-2 adrenergic receptors to the central nervous system (the brain), where it is active as a neurotransmitter.
As a pro-sexual drug, yohimbine has a definite edge over cocaine, amphetamine, and methamphetamine. The three street drugs may have the effect of causing sexual arousal, but at the same time interfere negatively with sexual function.
This is the case because hormonal epinephrine not only has the function to increase heart rate and blood pressure in order to make the body ready for fight or flight, but also to shut down functions that are not essential for fighting or fleeing. Blood is drawn from the digestive tract while bowel movement may be hastened to rid the body of weight.
Vasodilatation in the genital tract is made impossible. An erection during a fight would be an unwelcome obstacle, and a highly vulnerable target on top of that. This is why the increased catecholamine levels effected by cocaine, amphetamine, and methamphetamine all lead to a strong shrinkage of the male genitals. Therefore, what one gets from cocaine and amphetamines is a plus in desire and a minus in capability… an odd combination indeed.
Yohimbine, on the other hand, does not elevate epinephrine effects throughout the body. Yohimbine effects a minus of epinephrine in the abdominal and genital areas where alpha-2 adrenergic receptors prevail, and a plus of epinephrine in the central nervous system and other, mostly upper parts, of the human body.
In order to understand why the interference with alpha-2 adrenergic receptors works to facilitate erections, one has to know that the normal, flaccid genital state is, in the first place, only caused by hormonal epinephrine (adrenaline) being almost permanently docked to alpha-2 adrenergic receptors. To achieve an erection normally, nerve impulses will have to initiate a physiological process by which epinephrine (adrenaline) is removed from alpha-2 adrenergic receptors.
The same effect can be reached by ingesting some 5 to 50 milligram of yohimbine. "..........."
Yohimbe and yohimbine will make those who have ingested it easier to stimulate sexually. Yohimbe works mentally and physically towards this end, with both aspects strongly interacting. Men who normally have problems having an erection will feel a mental stimulation from the fact that a hard-on comes easy.
Yohimbe definitely increases erectile rigidity, and may increase erectile capacity. Yohimbe will definitely make orgasms more powerful. It will do this by postponing the point of ejaculation, and by making the orgiastic release more strongly felt. On the route to the orgiastic release, there will be a greatly accelerated heartbeat, caused by mental stimulation rather than physical effort"
