What do you think about this statement?

[casualbb]

You can say "genetic limit", but can you explain what inside the body makes you stop from going beyond?

The muscles in your body are in a state of constant flux.

Protein is flowing in and out at pretty quick rates. Most of the time protein in = protein out, and youi maintain muscle size.

Working out raises both protein in AND protein out, but protein in just a little bit more. Over time, gains can accrue.

Steroids will both INCREASE the protein in by triggering cellular growth and decrease the protein out by inhibiting cortisol. This will actually happen on its own without working out, but couple it with working out and there's a synergistic growth effect.

However as you get bigger and bigger, the amount of protein leaving the muscles increases (because there's more of them interacting with the blood), but usually the same amount of protein going in. THis is why you have to increase the steroid doses as you get bigger; you need a stronger "protein in" signal to counter the ever increasing "protein out" that results from growing very large.

Genetic limit just refers to a point at which a natural trainee, no matter how he trains or eats, cannot overcome the tendency for the body to breakdown the muscle tissue. ie protein out cannot be overcome with a training stimulus

 

[Makavelli]

This is the way I see it: When one introduces a supraphysiological amount of AAS into their system the androgen receptors on the muscle cells are filled rather quickly which causes hypertrophy of the cells. Thereby creating more receptors, which are then filled, etc. This will continue to occur until the level of receptors meets the level of androgens present. At which point muscle growth will slow dramatically or even come to a halt. Unless more androgens are added or the person can accept gaining much slower(at the pace of someone that is natural), then growth will be minimized. At this point there are more receptors than androgens. If this was not the case when one added more AAS at this point nothing would happen. But obviously when increasing the AAS employed something does happen-more growth. Assuming of course that the individual is eating enough, which was discussed above. JMO.

 

[Ulter]

You can say "genetic limit", but can you explain what inside the body makes you stop from going beyond?

If I did I would be working on the Human Genome Project instead of posting on Elite. No one knows the complete genetic code although muscle growth seems to be regulated by the myostatin gene.

 

[geoboy]

In my opinion, there are two little discussed dangers of steroids, both of which are very real. Although steroids do increase nitrogen retention, reduce muscle catabolism (tissue breakdown), and volumize muscle cells, steroid users are often disappointed with their results. Steroid use at the expense of proper nutrition and intense training often leads to no more than a temporary "bloat." .

Check

Even when combined with intense training and supportive nutrition, the body tends to build up a resistance to the drugs, bringing the enhanced muscle growth to a halt.

the mechanism might not be right, but the end result is for that cycle, and for that amt of the same drug.

As this tolerance develops, the muscle cells begin to develop more cortisol receptors. Cortisol is a catabolic hormone, thus, when the steroid use is stopped, the residual muscle stopped, the residual muscle breakdown is rapid.

complete and utter bullshit.

the breakdown immediately post-cycle is because of the reversal in the cortisol to testosterone ratio. you stop the exogenous steroids and your endogenous test production is shutdown. if you're on HRT or after you regain your natty test levels that acute breakdown stops. I havent seen any studies showing increased cortisol production or incresed # of cortisol receptors. this is a wives tale from early Bodybuilding lore. if anyone has studies to contrary I'd love to see them.

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