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What causes muscle growth?

Ok here goes

First you put strain on the muscle. The muscle then develops micro tears in at the cellular level. On the outside of each muscle cell more free nuclei can be created. The damaged cell encorporates more nuclei into itself. The cellular wall is replaced and then cell is now larger. Then through protein synthesis the cell is fortified to become a larger version of its previous self. Muscle cells are the only multi nucleatic cells in the body and react as a natural defense to outside attack (strain). This is why your muscles get bigger but never add more muscle cells.

Cheers,
Scotsman
 
There's these tiny magical gnomes that live inside your muscles. And all they want to do is sit around and read. But when you flex your muscles and work out, they get shaken around and it's hard to read. So afterwards, they get out their shovels and pick axes and start building stronger muscles, so that next time it will be harder for you to shake them around when they're reading.
 
JT Iron said:
There's these tiny magical gnomes that live inside your muscles. And all they want to do is sit around and read. But when you flex your muscles and work out, they get shaken around and it's hard to read. So afterwards, they get out their shovels and pick axes and start building stronger muscles, so that next time it will be harder for you to shake them around when they're reading.

Damn you are a smartass....I love it. How ya been bigness?

Cheers,
Scotsman
 
Do a search on p70s6k. It is the key translational factor for hypertrophy. Certain things phosphorylate it (activate it) like insulin, protein post work-out, and shitloads of other stuff. I'll go into more detail if you like (if you can't find good info on a search), but I'm kinda busy right now...so it will have to wait.
 
There has to be more to muscle growth than stimulation because a baby can sleep all day and still gain more muscle mass reletave to thier body weight than any anabolic supplemented athlete.
 
Schutzhund1 said:
There has to be more to muscle growth than stimulation because a baby can sleep all day and still gain more muscle mass reletave to thier body weight than any anabolic supplemented athlete.

That's genetic growth imprinting.

Cheers,
Scotsman
 
can you "kill" muscle cells?

like if you get punched in the left chest, you can get a bruse, and it damages cells, but does it damage muscle cells killing them causing them to get smaller? or pop and lose nuclei..


that would suck if bodybuilders had to not get trauma or it set them back, and fucked up symetry etc...
 
SublimeZM said:
can you "kill" muscle cells?

like if you get punched in the left chest, you can get a bruse, and it damages cells, but does it damage muscle cells killing them causing them to get smaller? or pop and lose nuclei..


that would suck if bodybuilders had to not get trauma or it set them back, and fucked up symetry etc...

Yeah if you tear or remove muscle it is gone. You can see some of the pro's old injuries where the muslce is shaped differently or there is a divot looking area in a muscle belly.

Cheers,
Scotsman
 
Singleton said:
I found this article: http://www.avantlabs.com/page.php?pageID=161&issueID=15

But it was not presented in a way that was accessible to my level of understanding. It doesn't lend it's self to application. I mean, whatever they're talking about isn't something I can use and apply.

The calcineurin pathway is pretty much a thing of the past anyways...it's been "proven" to be "wrong." They've pretty much got it narrowed down to the akt/mtor/p70s6k pathway. That's how IGF works...akt/mtor/p70s6k are all downstream of IGF. So basically IGF phosphorylates something, that phosphorylates something, that phosphorylates akt, then mtor (mammalian target of rapamycin) then eventually p70...the big boy.
 
Bulldog_10 said:
The calcineurin pathway is pretty much a thing of the past anyways...it's been "proven" to be "wrong." They've pretty much got it narrowed down to the akt/mtor/p70s6k pathway. That's how IGF works...akt/mtor/p70s6k are all downstream of IGF. So basically IGF phosphorylates something, that phosphorylates something, that phosphorylates akt, then mtor (mammalian target of rapamycin) then eventually p70...the big boy.


Thats it. Im calling you Professor now on.
 
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