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What are the negative effects of an anti-e while on?

McFakerton

New member
What are the downsides to running an anti-e while on? Obviously the upsides are no bloat, gyno prevention, etc; but I imagine there are negative aspects as well. If so, what are they?
 
if too much E suppression, dry skin, joints, lethargy and lowered libido. These sides are most common with letrozole.

lowered libido also very possible with nolva (over a third of users- in clinicals) (ER antagonism)
 
macrophage69alpha said:
if too much E suppression, dry skin, joints, lethargy and lowered libido. These sides are most common with letrozole.

lowered libido also very possible with nolva (over a third of users- in clinicals) (ER antagonism)
hey macro, u always give good advice and ur right once again, but i think he ment negative effects regarding his cycle, will taking an anti-e make u not get as strong as u would have maybe? thanks bro
 
a little estrogen can sometimes be a good thing, so complete and utter annihilation of estrogen is not preferred. a lot of people report strength gains with a slight increase in E
 
macrophage69alpha said:
if too much E suppression, dry skin, joints, lethargy and lowered libido. These sides are most common with letrozole.

lowered libido also very possible with nolva (over a third of users- in clinicals) (ER antagonism)


Aha! thats the culprit! I recently increased anastrozole because I increased my test amount by adding a little super test and was wondering why I was so much less of a horn dog. Thanks for the info!
 
mikefear said:
a little estrogen can sometimes be a good thing, so complete and utter annihilation of estrogen is not preferred. a lot of people report strength gains with a slight increase in E


Interesting. This has been good info!

I have been so focused on all the other stuff that I am taking that I guess I neglected this area a little.
 
Joint hurt, also one can get VERY moody, when my e levels are too supressed its the one time I am more prone to moodyness
 
OMEGA said:
Joint hurt, also one can get VERY moody, when my e levels are too supressed its the one time I am more prone to moodyness
estrogen is a bitch.. too little -- moody.. too much -- moody.. :mad:
 
McFakerton said:
What are the downsides to running an anti-e while on? Obviously the upsides are no bloat, gyno prevention, etc; but I imagine there are negative aspects as well. If so, what are they?

Nolvadex supresses GH/IGF-1 sythesis, which sucks. I think Nolva is becoming a dinosaur as better alternatives are discovered (AIFM/Aromasin/Proviron).
 
Hmm I run .25/.50 mg Arimidex for the entire cycle. Is this hindering my gains much? I blow up like a bloated fathead if I don't use it.
 
aromasin and AIFM are better than dex because they suppress estradiol more heavily and estrone less so. Allowing for some of the weaker estrogen, whereas dex completely suppresses the weaker and allows for the stronger.

they both also suppress shbg
 
A little bloat can go a long way in terms of strength gain, and this can be a good tool. Sometimes steroids like d-bol get a bad rap because critics attribute so much of the "gains" to water, and then dismiss the gains as "unkeepable" when their weight (both bodyweight and lifts) starts dropping upon cessation of the drug.

The truth is that the water weight was helping them to be strong, and to work at a level of intensity otherwise impossible. Not to mention the massive pump you get while holding a bit of extra water! I still get huge pumps when I’ve used an anti-e to stay pretty hard, but if I allow a little bloat pumps are off the hook! (And I do think there is a sound basis for some stimulation of hypertrophy associated with a chronically induced pump! Plus it kicks ass feeling like Kong Zilla after a session of legs and chest.)
 
I agree with a lot of stuff said on this thread. Im was using 1mg adex ed and my gains were not as big as I would like them to be and I was not as big of a hornball. I changed over to AIFM 2 weeks ago and do 3 sprays ed. I was just paranoid about getting gyno and lactating again that I used 1mg adex ed throughout most of the cycle....I obviously did not need that much and it definately hindered my gains. But....I did loose bf (with the help of sesapure and glucerall as well) and did not bloat at all. So I guess I cant look at it as getting more quality gains and less sides to look on the upside of things. You live and learn.
 
Letro makes me ache like I have the flu, even at 1.25mg EOD. I'm unsure as to how it's supposed to work vs adex - adex lowers estrogen by 50% while letro wipes out almost all of it, correct?


Is this only once a certain threshold has been passed in terms of daily doseage, or is it a case of more letro = less estro? Would taking low low dose letro (say .5 E3d) leave enough estro floating around to prevent aching bones and messed up lipid profiles?
 
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