It's changed my life. Good stuff. I hardly have anything negative to say about it so far. Everybody is different though. Here's something I posted on a thread awhile back:
I'm on 300mg/day of Wellbutrin SR. It's great. I'm not "zombied out", and I'm still aware of things I need to do in my life to make it better. I think a lot of people think that anti-depressants are just an easy way out or something and they will take away all motivation to do anything with your life. I know that some people report more sedative effects with some of the drugs that predominantly effect serotonin levels, but I haven't tried those so I can't speak from firsthand experience.
Common problems with a lot of anti-d's are sexual disfunction and a sedative effect. I chose Wellbutrin because it primarily affects dopamine and norepinephrine. People generally report increased sex drives and energy levels, and it is even being studied as a possible weight loss drug. This is mentioned in a muscle magazine this month, according to this week's "Ghost Dawg" column at
www.t-mag.com. The same chemical- bupropion hydrochloride- is marketed under the name "Zyban" as an aid for those trying to quite smoking. Anyway, I knew that I like dopaminergic substances and stimulants (adderall, for example- which I have a scrip for now too), so I figured that if Wellbutrin kind of leaned in that direction than it was the drug for me. And I really value my hard-ons. Wellbutrin is the shit. I enjoy my days like they should be enjoyed, instead of worrying about bullshit or having this undefined feeling of gloom and doom that may descend at any time for no apparent reason and stay for god knows how long. And when I'm in a good mood, I'm not sitting there thinking in the back of my mind, "Man, I know I'm going to crash at any time." I still have my worries, but they're manageable. I still get irritable about things sometimes, but I don't punch holes in my wall anymore and tear my door off the hinges (damn, that was getting expensive too). Everyone- friends, family, coworkers- have noticed a difference. Instead of getting comments like, "Man, you look pissed off most of the time.", people say, "What are you so cheerful about?" I also don't feel like drinking much anymore- the desire just isn't there, which is good after my episode over the summer that I've posted about. Drinking decreases its effectiveness anyway, and since I've laid off the booze it really kicks in good.
A nice little bonus is that they use it in mild cases of ADD- it's that dopamine/norepinephrine connection- so you do find it somewhat easier to focus and pull up words that usually sit on the tip of your tongue.
As far as addiction- anything that has a profound impact on your brain will probably be addictive if you have to take it every day. That's just something you have to accept. You can still wean off of it, but I've never tried, nor do I want to. It's not a toxic drug and I'm sure the benefits from laying off the booze far outway any mild effects it may have on liver values. Oh, another cool thing about Wellbutrin is that it doesn't have a million and one interactions with other drugs like the MAOI's and Tricyclics do.
I wasn't sure I wanted to commit to taking an anti-depressant for a long time either, but finally I made myself go in and I'm sure glad I did. Like I said, I still have life problems and I still have emotions, but life is better and things just seem more manageable. Life doesn't seem to be crushing down on me all the time, while at the same time I'm kicking myself for feeling like shit when I really have it so good compared to so many in the world. It sucks when emotions and rational thought are at odds with each other like that. If you feel down all the time for no reason, go ahead and check it out. Another anti-d might suit you better- who knows- but give something a shot. My doc said some people just take their Wellbutrin during the winter months when they're more prone to the blues and then ween off in the spring. My sister is on Wellbutrin too and she has quit taking it before and then started up again. It's not like you're taking a step from which you can never turn back.
Anyway, I hope this post was somewhat coherent and helped you out a little. I have to leave for the night.
Y'all take 'er easy.