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UG LrHGH

WannaImpress

WannaImpress

New member
Ok guys I know several of you guys have heard about the recently released long acting rHGH from an UG Lab. Just wanted to get some feedback on this particular product!:D
 
WannaImpress said:


LOL, greedy with that Karma aren't you? Better hit me back up! Bump for Fonz!:D
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Good stuff.

Been on it for a month and can already see a difference. My chest didn't grow worth beans for 3 years no matter how i trained it, and now its finally strating to grow after I added the GH.

Doesn't have to be refrigerated either, which is a huge bonus.

Fonz
 
Fonz said:


Good stuff.

Been on it for a month and can already see a difference. My chest didn't grow worth beans for 3 years no matter how i trained it, and now its finally strating to grow after I added the GH.

Doesn't have to be refrigerated either, which is a huge bonus.

Fonz
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Not to mention it's a lot less expensive than Nutropin Depot.
 
Fonz said:


Good stuff.

Been on it for a month and can already see a difference. My chest didn't grow worth beans for 3 years no matter how i trained it, and now its finally strating to grow after I added the GH.

Doesn't have to be refrigerated either, which is a huge bonus.

Fonz
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Very nice Fonz. Quick ?'s if you don't mind. Does it come pkgd. all pretty in a box like the Nutropin Depot/hologramed and how often do you shoot it? Also why doesn't it have to be refrigerated?
 
Can't do it. Ask Fonz why, You can email me though. It is that ok Fonz?
 
WannaImpress said:


Very nice Fonz. Quick ?'s if you don't mind. Does it come pkgd. all pretty in a box like the Nutropin Depot/hologramed and how often do you shoot it? Also why doesn't it have to be refrigerated?
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2 vials. One with a wafer and one with the solution(3ml).

You mix the two and inject Sub-Q. Thats it. :)

You can either shoot it once a month(3ml) or once every 2 weeks(1.5ml).

The Nutropin solution is very delicate(Hence refrigeration is needed). The UG solution is far more resistant to heat.

Fonz
 
WannaImpress said:


JA, I know who this UG Lab is but why can't we let it out yet? Just curious bro.:)
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Ask Fonz. PM or email him. There are specific reasons for it.
 
WannaImpress said:


JA, I know who this UG Lab is but why can't we let it out yet? Just curious bro.:)
Click to expand...

Remember what happenned to IP...when everybody mentioned his name on every board?

Same thing applies here. No commentary on the manufacturer, just the product.

Fonz
 
Juice Authority said:
Can't do it. Ask Fonz why, You can email me though. It is that ok Fonz?
Click to expand...

Yes, thats fine.
 
Also, what's your guys opinions on UG Labs not being able to develope LrHGH for the reason that is is extremely expensive up to 100k in equipment to make this particular product or is it something they relabel themselves?
 
WannaImpress said:
Also, what's your guys opinions on UG Labs not being able to develope LrHGH for the reason that is is extremely expensive up to 100k in equipment to make this particular product or is it something they relabel themselves?
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I read that little quote from steirodology...and found it quite funny.

$100k? LOL.......not quite.

Anyways, they probably buy the wafers at wholesale prices.

Fonz
 
Fonz said:


I read that little quote from steirodology...and found it quite funny.

$100k? LOL.......not quite.

Anyways, they probably buy the wafers at wholesale prices.

Fonz
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LOL, yeah that's where I got it from. So Fonz in your opinion is this UG LrHGH better or as good as the Nutropin Depot? By the way since it releases 2+IU's/ed does interfere with your own production of GH?
 
At thesse prices and the fact that it doesn't have to be shipped on ice nutropin is going to lose a lot of market share. Oh well.
 
WannaImpress said:
Hey hey now, since I started this post I suggest you all hook me up wth some Karma!:D
Click to expand...

You have given out too much Karma today, try again later. Tomorrow Bro.
 
Juice Authority said:
At thesse prices and the fact that it doesn't have to be shipped on ice nutropin is going to lose a lot of market share. Oh well.
Click to expand...

Yeah the price is definitely attractive and not having to be shipped cold is a plus but from my understanding HGH has always been needed to be shipped cold except for........damn I can't recall the brand right now. Bump for more input!



Juice Authority said:


You have given out too much Karma today, try again later. Tomorrow Bro.
Click to expand...

Way too much Karma, yeah right......just look at my ONE whole green block, wow!:D

Fonz, I'm still a little leery regarding interference of your own production though, if you could elaborate I would greatly appreciate it.
 
WannaImpress said:


Yeah the price is definitely attractive and not having to be shipped cold is a plus but from my understanding HGH has always been needed to be shipped cold except for........damn I can't recall the brand right now. Bump for more input!





Way too much Karma, yeah right......just look at my ONE whole green block, wow!:D

Fonz, I'm still a little leery regarding interference of your own production though, if you could elaborate I would greatly appreciate it.
Click to expand...

Any kind of exogeneous GH will interfere with your own production. Doesn't matter if its long acting or dhort scting.

Fonz
 
WannaImpress said:


Fonz, I'm still a little leery regarding interference of your own production though, if you could elaborate I would greatly appreciate it.
Click to expand...

What do you think Nutropin and other the other GH does?? Same as AAS but you do recover.
 
has anyone had this GH tested? has anyone other then fonnz used it? this shit sounds almost to good to be true, and an UG lab has the capabilities to produce it? need more feedback please
 
alltraps said:
has anyone had this GH tested? has anyone other then fonnz used it? this shit sounds almost to good to be true, and an UG lab has the capabilities to produce it? need more feedback please
Click to expand...


Bump
 
OXANDRIN said:
so what size needle is needed? and how many cc would 1 dose of 22.5mg equal?
Click to expand...

I would use a 30 guage but check with Fonz...
 
OXANDRIN said:
sub-q...a 28 gauge works well.... but most slin darts only hold 100iu or 1cc
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That should be fine but check with Fonz.
 
OXANDRIN said:
sub-q...a 28 gauge works well.... but most slin darts only hold 100iu or 1cc
Click to expand...

I used a 25 gauge 5/8" pin...but mostly because I had a few 100 of them lying around because I also shoot ALcar sub-Q as well.

A 28 gauge would work just as well.

Fonz
 
Fonz said:


I used a 25 gauge 5/8" pin...but mostly because I had a few 100 of them lying around because I also shoot ALcar sub-Q as well.

A 28 gauge would work just as well.

Fonz
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I can't wait to get my kit!! Not many people have it. None of the Supra remailers have access to it.
 
Hey Fonz - The only way I know that a 191 residue protein can be synthesized efficiently is with an automated protein synthesizer. $100k doesn't sound like an outrageous price for that kind of sophisticated equipment, not to mention the reagents needed to use the machine are not cheap either. How is it that a UG lab can afford that kind of equipment?

This is not meant as a flame or anything but I would suspect any HGH product from an UG lab to be a fake unless they were buying the HGH wafers from a bonafide pharmaceutical company and re-selling them. I just can't see Joe wannabe chemist brewing up HGH in his bathtub.

I am glad you are getting good results though. Have you had it tested to verify it is genuine?
 
Hey Fonz - The only way I know that a 191 residue protein can be synthesized efficiently is with an automated protein synthesizer. $100k doesn't sound like an outrageous price for that kind of sophisticated equipment, not to mention the reagents needed to use the machine are not cheap either. How is it that a UG lab can afford that kind of equipment?
Click to expand...


bump. thats what i want to know
 
Spidey said:


unless they were buying the HGH wafers from a bonafide pharmaceutical company and re-selling them.
Click to expand...

You hit the nail on the head there. :)

Fonz
 
I hear this stuff is the best long-acting GH available (in limited supply).

Bump
 
Yeah George, buy some more by hook or by crook before it’s all gone. Sell some shares, that’s what I did. Actually I borrowed against some shares. I like doing that because it’s a sweet tax loophole. Hopefully I’ll receive by end of week. I’ll snap some pictures.
 
benevolent anarchist said:
Yeah George, buy some more by hook or by crook before it’s all gone. Sell some shares, that’s what I did. Actually I borrowed against some shares. I like doing that because it’s a sweet tax loophole. Hopefully I’ll receive by end of week. I’ll snap some pictures.
Click to expand...

Check your PM.
 
is ANYONE other then FONZ using this? anyone at all?

not that i dont trust fonz, its just that i like to get a few more critiques of this before i splurge my life savings. i dont think im the only one that needs more then one person to convince me, no matter how credible they are ie fonz

bump
 
alltraps said:
is ANYONE other then FONZ using this? anyone at all?

not that i dont trust fonz, its just that i like to get a few more critiques of this before i splurge my life savings. i dont think im the only one that needs more then one person to convince me, no matter how credible they are ie fonz

bump
Click to expand...

Not many people at EF using it. They are mostly at AF.

Fonz
 
hate to burst any bubbles here, but... there is no method to meter release of rhGH. Any claims to the contrary are bullsh*t.

All rhGH denatures rapidly once reconstituted. What is this shit, magical?
 
riskarb said:
hate to burst any bubbles here, but... there is no method to meter release of rhGH. Any claims to the contrary are bullsh*t.

All rhGH denatures rapidly once reconstituted. What is this shit, magical?
Click to expand...


Hate to burst your bubble, but here is a commercially available product called Nutropin that is a one-shot per month rHGH. You can look it up on the web.


As far as a UG lab having access to this type of product, I guess will have to wait and see. This is a new one and the verdict is still out.
 
Holy sh*t, and I make a market in DNA options... hadn't heard of the dev. of depot.

<bad karma for moi>

sorry guys, disregard -- although I wonder what the practical half-life would be. I would certainly prefer to use the short-acting to limit endo-suppression.

I've been on Saizen for a year, love the stuff.
 
buckwheat1 said:
I believe the GH is embeded in microspheres that dissolve over time releasing the GH.
Click to expand...
Yep, you got it, as far as the Genetech version.
How does Nutropin Depot work?
Nutropin Depot consists of thousands of tiny balls (microspheres) made of a substance commonly found in medical products such as the "thread" used for dissolvable stitches. Each of these microspheres contains molecules of GH. Once Nutropin Depot suspension is injected under the skin (subcutaneously), its microspheres degrade, releasing the GH into the body in 2 phases—this is known as biphasic release. About 50% of the drug is released within the first day or two after the injection, and the remainder is released in the secondary (long-acting) phase as the microspheres degrade.
Click to expand...
 
Anyone have an opinion on how this would compare to ED injections? Besides the convenience factor of course.

One of the "problems" with exo-GH use, and SC injections, is that the IGF-1 releases are more like spikes as the GH diseminates from the fatty tissue relatively quickly. You can get a more even release with IM injections, but then bioavailabililty drops from low 80% range to somewhere in the 60% range.

Let's say one were to compare regular GH ED to L-rHGH. Would the encapsulation of the GH lead to greater bioavailabilty such that 2iu ED of long gives more bang for the buck than 2iu of regular? Would the slow release of the long version help with sustaining IGF-1 release and eliminating the spike seen with ED injections?
 
thx9000 said:
okay, last try....
Click to expand...

The only one that I know who has been on this particular long-acting GH for any length of "noticeable" time is Fonz. That's it. I get my kit this week but the results from the long-acting HGH aren’t going to be instantaneous. It takes several months to notice a change in body chemistry so be prepared to bust out some $$$.
 
Statement from Nutropin Depot site (little cropped but gets the message across)


Estimates of relative bioavailability for a single dose of Nutropin Depot ranged from 33% to 38% when compared to a single dose of Nutropin AQ® [somatropin (rDNA origin) injection] in healthy adults, and from 48% to 55% when compared to chronically dosed Protropin® (somatrem for injection).

I'll take the daily injections over the bi-monthly or monthly.
 
Kepeli said:
Statement from Nutropin Depot site (little cropped but gets the message across)


Estimates of relative bioavailability for a single dose of Nutropin Depot ranged from 33% to 38% when compared to a single dose of Nutropin AQ® [somatropin (rDNA origin) injection] in healthy adults, and from 48% to 55% when compared to chronically dosed Protropin® (somatrem for injection).

I'll take the daily injections over the bi-monthly or monthly.
Click to expand...

Damn, I will have to look and see where I got numbers of 83% for SC and 67% for IM on the daily dosed version.
 
http://boards.elitefitness.com/foru...d=266900&highlight=Medical+community+Nutropin

J Pediatr Endocrinol Metab. 2002 May;15 Suppl 2:715-22. Related Articles, Links


A long-acting human growth hormone (Nutropin Depot): efficacy and safety following two years of treatment in children with growth hormone deficiency.

Silverman BL, Blethen SL, Reiter EO, Attie KM, Neuwirth RB, Ford KM.

Department of Pediatrics, Northwestern University, Chicago, IL, USA. [email protected]

BACKGROUND: Nutropin Depots [somatropin (rDNA origin) for injectable suspension] is a long-acting form of human growth hormone (GH) to be administered by subcutaneous (s.c.) injection. The availability of this formulation offers the opportunity for greater convenience and compliance by decreasing the number of injections and frequency of administration required. OBJECTIVE: To determine the efficacy and safety of a long-acting formulation of GH administered in children with GH deficiency (GHD) once or twice monthly for 2 years. PATIENTS: Fifty-six previously untreated, prepubertal children with GHD received Nutropin Depot 1.5 mg/kg once monthly (1x/mo), or 0.75 mg/kg twice monthly (2x/mo) for 24 months. The mean pretreatment growth rate was 5.0 +/- 2.4 cm/yr. RESULTS: The 0-12 mo growth rate (mean +/- SD) was 8.3 +/- 1.5 cm/yr in the 1x/mo group and 8.2 +/- 2.0 cm/yr in the 2x/mo group. The 12-24 month growth rate was 7.2 +/- 1.5 cm/yr in the 1x/mo group and 6.9 +/- 1.5 cm/yr in the 2x/mo group. During the 24 months of treatment, height standard deviation score (SDS) increased by 1.0 +/- 0.5 SD in the two groups combined (p <0.0001). The corresponding advancement in bone age was 2.2 +/- 0.7 yr, resulting in a gain in Bayley-Pinneau predicted adult height (PAH) SDS of 0.6 +/- 0.9 SD in the 1x/mo group and 0.6 +/- 1.0 SD in the 2x/mo group. No serious adverse events attributable to the study drug were reported. Injection site reactions were common, but resolved without intervention. Pre-dose fasting and postprandial glucose and insulin levels, as well as hemoglobin A1c levels, were unchanged from baseline values. CONCLUSIONS: Treatment with Nutropin Depot is associated with catch-up growth and normal skeletal maturation and is a viable alternative to daily injections of GH in children with GHD.

Publication Types:
Clinical Trial
Multicenter Study

PMID: 12092685 [PubMed - indexed for MEDLINE]
 
Kepeli said:
Statement from Nutropin Depot site (little cropped but gets the message across)


Estimates of relative bioavailability for a single dose of Nutropin Depot ranged from 33% to 38% when compared to a single dose of Nutropin AQ® [somatropin (rDNA origin) injection] in healthy adults, and from 48% to 55% when compared to chronically dosed Protropin® (somatrem for injection).

I'll take the daily injections over the bi-monthly or monthly.
Click to expand...

Okay, I thought about this.

Nutropin is heat sensitive, and this UGL stuff supposedly isn't. So, I'm not sure we can apply this study to the UGL product. I say this because Nutropin will be wandering around or in depot in your 98C body for up to 28 days which can't be too good for the product's bioavailability.
 
Nutropin AQ is heat sensitive. Nutropin Depot shouldn't be if it is to be time-released over a 2-4 week period. This is just a guess, though. I will go look and see. I cant see them marketing a product that degrades too quickly in the body.
 
Last night before bed I started feeling a little ornery. When I woke up to go to the bathroom, you can imagine my shock and horror when I looked in the mirror and saw a green face staring back at me. I had become the Incredible Hulk.

Smartass comments aside, I realize you guys are hungry for feedback, but you are just going to have to wait if you want detailed results. Unlike AAS, the gains from rHGH come slowly and steadily. Also this product just came out and most people are only on their first month or so. I’m only on my second week. The general feedback from those who are using it is very good and I can tell you this. The stuff feels like good rHGH. Not trying to sound condescending, but if you think that sounds hokey and you don’t know what I mean, then I don’t think you’ve ever used good rHGH.

Stay tuned. :)
 
People, the issue of heat sensitivity is strictly in shipping and handling of the product. All Hgh is heat sensitive Even Serostim should not be exposed to heat. This is the main problem when dealing with street Hgh. Handling of the product during the spring / summer months kills the rDNA.

Think about it, you guys are being to analytical. There is no difference in body temperatures from Adults to Children. Nutropin Depot has a pediatric indication by the FDA. It works in kids, The shorter acting Nutropin AQ works better because it mimics closer to natural Hgh release in the body. All pediatric doses are given at night.

The UGL that released there version of long acting Hgh does not have to be refrigerated by their claims. I would like to see how their delivery system compares to Nutropin Depot? If I had to bet, it will not even shine the shoes of Nutropin Depot. But to be fair, Supra does make a good product.

The bottom line is Nutropin Depot delivers the goods in a BIG way. The adult clinical trials with the depot are being completed as we speak. But take the indication with a grain of salt. They are not studying this fine product for BB or athletic purposes.

All Hgh should never be exposed to heat. That is already a given.
 
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