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Trans dermal info for everyone
- Thread starter lord_regulator
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lord_regulator
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Transdermal is still only going to get at best 20-30% absorption. Esterified drugs can be used, since there are esterases present in the tissues, which will release the free drug.
Also, primobolan depot can be taken orally, since it is the 1-methyl group that confers protection from metabolism, not the ester.
Also, primobolan depot can be taken orally, since it is the 1-methyl group that confers protection from metabolism, not the ester.
Montecristo
New member
Ok, you guys mentionned molecular weight as a determining factor here. What about base ie: Sustanon 250 can be based on oil or alcohol... Think you could use this with an oil based sustanon like the nile stuff...
lord_regulator
New member
Yes i see we are finally geting some tru scientists on board here
I have always said that through education you will atain your greatest goals for any body who truly wants to learn the chemical make up of specific anabolics and drugs go to http://www.steraloids.com/trivindx.html
i have found it great for chemical formula,Molecular Weight,Melting Point,Rotation
I have always said that through education you will atain your greatest goals for any body who truly wants to learn the chemical make up of specific anabolics and drugs go to http://www.steraloids.com/trivindx.html
i have found it great for chemical formula,Molecular Weight,Melting Point,Rotation
kickboxer99
New member
Cockdezl---Why is it only effective for 20-30% absorbtion? Does anyone else have any idea what the absorbtion rate is?
lord_regulator
New member
The real absobrtion rate for Trans Dermal is eighty percent not twenty to thirty percent
"The real absobrtion rate for Trans Dermal is eighty percent not twenty to thirty percent"
REGULATOR, if you can give me one study that shows a formulation which gives 80% recovery of an applied hormone, I would be a happy man. I'd have that shit made up and would be selling it right now. Look up the research...transdermals have a tough time fighting their way through the stratum corneum.
"Okay let's get this straight here....is it because of the ester or the parent compound that makes it orally available? Is this why Trenbolone acetate is purported to be orally active?"
The ester is what gives an INJECTABLE drug its half-life. It modifies the drug's potential to remain in it's vehicle (oil or water), or to exit the vehicle and enter the tissues/blood.
Chemical modification of the base drug is what gives the majority steroids protection from hepatic metabolism. Most are 17-alpha alkylated, some are 1-alkylated. The exception is Andriol (testosterone undecanoate). This drug is orally active, due to its highly lipophilic ester, which partitions itself in chylomicrons and is taken up by the lymphatic system. Unfortunately, it tends to remain in the chylomicrons, thus giving very low release and effects.
REGULATOR, if you can give me one study that shows a formulation which gives 80% recovery of an applied hormone, I would be a happy man. I'd have that shit made up and would be selling it right now. Look up the research...transdermals have a tough time fighting their way through the stratum corneum.
"Okay let's get this straight here....is it because of the ester or the parent compound that makes it orally available? Is this why Trenbolone acetate is purported to be orally active?"
The ester is what gives an INJECTABLE drug its half-life. It modifies the drug's potential to remain in it's vehicle (oil or water), or to exit the vehicle and enter the tissues/blood.
Chemical modification of the base drug is what gives the majority steroids protection from hepatic metabolism. Most are 17-alpha alkylated, some are 1-alkylated. The exception is Andriol (testosterone undecanoate). This drug is orally active, due to its highly lipophilic ester, which partitions itself in chylomicrons and is taken up by the lymphatic system. Unfortunately, it tends to remain in the chylomicrons, thus giving very low release and effects.
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