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thebabydoc
New member
So let me see if I get this right...
Your references are from a diet book?
And your data is from heretofor unpublished research at Baylor?
What did you say you were before you started writing prescriptions for a living?
Evista:
Use:
Known colloquially as the "designer estrogen", Raloxifene or Evista is an
alternative to estrogen for preventing bone loss in postmenopausal women.
How It Works:
Raloxifene or Evista is a selective estrogen receptor modulator meaning that it
affects some, but not all of the same receptors that estrogen does. In some
instances, it antagonises or blocks estrogen. It acts like estrogen to prevent bone loss and improve lipid profiles, but it has the potential to block some estrogen effects such as those that lead to breast cancer and uterine cancer.
Side Effects:
Being and estrogen-like substance, Raloxifene or Evista has estrogen-like side
effects, for example nausea, vomiting, changes in cycles. However, in general,
it is well tolerated.
Cautions for People:
Because Raloxifene or Evista does have estrogen-like effects, it must be used
with caution by women who could not normally use estrogen, for example
those with breast cancer or uterine cancer. However, as more is understood
about the drug's antagonist effects, it may be a suitable alternative to estrogen
for these women.
Drug Interactions:
Raloxifene or Evista with its estrogen-like effects can affect blood clotting and thus must be used with care in combination with other drugs that affect blood
clotting, for example the warfarin anticoagulants.
Further Reading:
J Bone Min Res 1996;11:835
Obstet Gynocol Surv 1996;51:45
And from the makers of Evista:
http://www.evista.com/about_patient_info.html
-Lowers cholesterol. EVISTA lowers total cholesterol by about 7% and LDL
("bad") cholesterol by about 11%. It does not change HDL ("good")
cholesterol.
-No increased risk of breast cancer. In clinical studies, women taking EVISTA
had no increased risk of breast cancer or uterine cancer.
You idiot. Drugs have side effects, and although you might use AS because the "benefits" to BB's are clear and the risks well-understood, you would NOT use a new drug like Evista for an off-label use like you are suggesting. Furthermore, the doses needed to achieve effects on estrogen receptors in the human body are extremely small, just enough to prevent osteoporosis, and no studies have been done on humans to figure out the effects of higher doses which would be required to even begin achieving the effect you are speculating even exists.
It would be far more reasonable to use birth control pills, as these significantly increase the circulating levels of Sex Hormone Binding Globulin (SHBG), thereby tying up free testosterone and estrogen from binding elsewhere in the body.
By the way, whose password are you using to get on WEBMD for doctors?
Your references are from a diet book?
And your data is from heretofor unpublished research at Baylor?
What did you say you were before you started writing prescriptions for a living?
Evista:
Use:
Known colloquially as the "designer estrogen", Raloxifene or Evista is an
alternative to estrogen for preventing bone loss in postmenopausal women.
How It Works:
Raloxifene or Evista is a selective estrogen receptor modulator meaning that it
affects some, but not all of the same receptors that estrogen does. In some
instances, it antagonises or blocks estrogen. It acts like estrogen to prevent bone loss and improve lipid profiles, but it has the potential to block some estrogen effects such as those that lead to breast cancer and uterine cancer.
Side Effects:
Being and estrogen-like substance, Raloxifene or Evista has estrogen-like side
effects, for example nausea, vomiting, changes in cycles. However, in general,
it is well tolerated.
Cautions for People:
Because Raloxifene or Evista does have estrogen-like effects, it must be used
with caution by women who could not normally use estrogen, for example
those with breast cancer or uterine cancer. However, as more is understood
about the drug's antagonist effects, it may be a suitable alternative to estrogen
for these women.
Drug Interactions:
Raloxifene or Evista with its estrogen-like effects can affect blood clotting and thus must be used with care in combination with other drugs that affect blood
clotting, for example the warfarin anticoagulants.
Further Reading:
J Bone Min Res 1996;11:835
Obstet Gynocol Surv 1996;51:45
And from the makers of Evista:
http://www.evista.com/about_patient_info.html
-Lowers cholesterol. EVISTA lowers total cholesterol by about 7% and LDL
("bad") cholesterol by about 11%. It does not change HDL ("good")
cholesterol.
-No increased risk of breast cancer. In clinical studies, women taking EVISTA
had no increased risk of breast cancer or uterine cancer.
WRONG. It was thought that Tamoxifen might be such a drug but this ain't panning out so well, either.
You idiot. Drugs have side effects, and although you might use AS because the "benefits" to BB's are clear and the risks well-understood, you would NOT use a new drug like Evista for an off-label use like you are suggesting. Furthermore, the doses needed to achieve effects on estrogen receptors in the human body are extremely small, just enough to prevent osteoporosis, and no studies have been done on humans to figure out the effects of higher doses which would be required to even begin achieving the effect you are speculating even exists.
It would be far more reasonable to use birth control pills, as these significantly increase the circulating levels of Sex Hormone Binding Globulin (SHBG), thereby tying up free testosterone and estrogen from binding elsewhere in the body.
By the way, whose password are you using to get on WEBMD for doctors?
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