T3 ^ Attention Theorists, Users

[Silent Method]

I’ve been looking at the current popular T3 theory and usage recommendations. I have some questions that I think are worth looking into. Consider the following:

T3 Assumption #1 – Exogenous T3 will not permanently shut down thyroid function (thyroid hormone output). Instead, use of T3 will only cause a temporary thyroid shutdown.

First let me say that I believe very strongly that interrupting any natural body system has the potential to harm that system. The longer the interruption, the greater the chance that harm will occur.

That being said, I agree that the chance of exogenous T3 permanently shutting down your thyroid is very unlikely. I have seen studies that included people taking T3 at 400mcg/day for many months and, upon cessation, normal thyroid function is restored after several months.

It is a fact that 50-75mcg of exogenous T3 will halt natural thyroid hormone output. Lesser amounts are inhibitory to a lesser degree.

It has been proposed by some that 12.5mcg of T3 is probably not inhibitory to any appreciable degree. What evidence do we have for this?



T3 Assumption #2 – Regarding T3 use by healthy persons, it is widely accepted that a pyramid dosing pattern is the “safest” method of use.

Recent theorists have proposed that the “ramp up” portion of the pyramid is of little if any value. In fact, some solid arguments have been made that the ramp up may do more harm than good. Still, it is generally accepted (and I believe wisely so) that a short ramping up phase is favorable, reducing the suddenness of shock to the thyroid as well as allowing the user to assess the effect of the drug.

Regarding the ramp down, it would seem to me that, having already shut your thyroid down, simply reducing subsequent doses to lesser and lesser inhibitory levels would serve only as a buffer for the effects of hypothyroidism suffered by the T3 user.

Ignoring the typical effects of systemic “rebound” (i.e. sluggish metabolism, increased fat storage, etc) might it be beneficial in regards to thyroid health to skip the ramp down in order to lessen the amount of time exogenous T3 exists in the body?

What evidence do we have that the ramp down is necessary, or has any effect at all, regarding restoration of natural thyroid function?

 

[Silent Method]

input?

 

[AUcowboy]

My brother had a shitty thyroid and the doc put him on t3(he only wieghed 165??) but after a few months he took him off and his thyroid started running at normal rates again. So i too believe that cycling shuts down t3 production, but in the long run your body adapts most of the time.

But my best advice to give to someone taking t3 would be to run some sort of anabolic with it unless you wanna see your muscles evaporate. I ran it at 25-50-75-50mcg right after all the "coming off therapy" after my first cycle to cut up and i went from 16in not flexed biceps to 14in in the 4 weeks. Needless to say live and learn, <----me venting my anger....great post though

n

 

[Silent Method]

bump

 

[Elapid]

I'm glad you posted this, because I think there is a lot of bad side effects associated with this drug that haven't been seen first hand by most users or documented by the medical community and then there's the typical "my sisters husbands best friend's thyroid shut down while on 75mcg" bullshit.

Don't get me wrong, I think its healty to be cautious of drugs that affect things as important as our thyroid, but I can only remember one post in the last year about someone having thyroid problems after taking t-3.

Also, I think ramping up is a waste of time but I would the first time to make sure you know what dosage you can tolerate. I've used T-3 twice as high as 125mcgs and its my opinion that it works very well to get you over fat loss sticking points.

War Lobo used to post good stuff about T-3 over on the Womens Discussion Board.

 

[Silent Method]

Thanks for your input. It'd be nice if there was a nice little "one size fits all chart" detailing doses and durations correlated with degree and duration of thyroid shutdown, including recovery characteristics. I fear its not that simple. Anyone wanna take a crack at the first post here?

 

[Amp]

Proof through blood test

I took 75mcg for 4 weeks straight. A few days later I had blood work done and my TSH were normal.

I did Lipokinetix for 4 weeks (which is still on shelves) and after bloodwork I had low TSH levels, which did rebound after 4 weeks once I got tested again a month later.

So from now on I stay on an ECA stack with T3 at 75mcg daily for about 6 weeks to cut up. Using gear of course to maintain muscle mass.

 

[fhg43]

I’ve been looking at the current popular T3 theory and usage recommendations. I have some questions that I think are worth looking into. Consider the following:

T3 Assumption #1 – Exogenous T3 will not permanently shut down thyroid function (thyroid hormone output). Instead, use of T3 will only cause a temporary thyroid shutdown.

First let me say that I believe very strongly that interrupting any natural body system has the potential to harm that system. The longer the interruption, the greater the chance that harm will occur.

That being said, I agree that the chance of exogenous T3 permanently shutting down your thyroid is very unlikely. I have seen studies that included people taking T3 at 400mcg/day for many months and, upon cessation, normal thyroid function is restored after several months.

It is a fact that 50-75mcg of exogenous T3 will halt natural thyroid hormone output. Lesser amounts are inhibitory to a lesser degree.

It has been proposed by some that 12.5mcg of T3 is probably not inhibitory to any appreciable degree. What evidence do we have for this?

I would compare this low level hormone supplementation that we see with hormone deficiencies-it is a low level that doesn't inhibit or replace normal hormonal output. However it may not have a significant impact on the the metabolism of the user. Typically T3 is taken to create a 'suprphysical' level to induce a catabolic fat burning state. If dosage doesn't reach supraphysical states then thyroid function has less of a chance of shutting down. This is my theory at least.

T3 Assumption #2 – Regarding T3 use by healthy persons, it is widely accepted that a pyramid dosing pattern is the “safest” method of use.

Recent theorists have proposed that the “ramp up” portion of the pyramid is of little if any value. In fact, some solid arguments have been made that the ramp up may do more harm than good. Still, it is generally accepted (and I believe wisely so) that a short ramping up phase is favorable, reducing the suddenness of shock to the thyroid as well as allowing the user to assess the effect of the drug.

Regarding the ramp down, it would seem to me that, having already shut your thyroid down, simply reducing subsequent doses to lesser and lesser inhibitory levels would serve only as a buffer for the effects of hypothyroidism suffered by the T3 user.

Ignoring the typical effects of systemic “rebound” (i.e. sluggish metabolism, increased fat storage, etc) might it be beneficial in regards to thyroid health to skip the ramp down in order to lessen the amount of time exogenous T3 exists in the body?

What evidence do we have that the ramp down is necessary, or has any effect at all, regarding restoration of natural thyroid function? [/B]

Like any substance that affects hormonal levels it should be cycled and tapered-more so for health reasons than anything else. You could just quit using it, but I think the crash would be very dramatic and negate many of the benefits of the cycle. By tapering off you may continue to benefit from the substance and reduce crash effects. Recovery time may be the same as if you just quit using T3, but your body may retain more of the gains (or losses in this case).

IMO T3 is a very very individual drug. Some people have tremendous metabolisms and might need a high dosage to benefit from the drug. Some people may benefit from low doses. If some one has a super metabolism they may get nothing from the 12.5-25mg dose.

It is totally dosage dependant but IMO the best course of action for health and benefit, from all the experiences and research done on the board, is to ramp up fast hold the peak for a short amount of time and taper long. some one had a formula that spelled it out and I can't find it. It went something like:

15% of cycle: ramp up
25% of cycle: peak
60% of cycle: taper

And again this drug has various effects. Some people report they screw their thyroids-I believe them. some people say that 400mgs is great and they experince no ill effects-I believe that too. I'd say for the first cycle start low and do a short cycle see what effects it has.

FHG

 

[BigAndy69]

The bottom line is that no matter what you are hurting yourself when using T3. I don't see the point in a long ramp up because you ae wasting your time.

I'm in the middle of a T3 crash, and I felt as soon as I got down t 25mcg, I can't imagine what I would have felt if I had stopped without a ramp down

 

[Silent Method]

Thanks for all your input guys. It'd be nice if pharmakinetics was cut and dry and we had nice little charts and graph that always worked.