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Restoring serotonin levels and natural sleep aids

soflaguy

New member
After the cyclical use of Ambien, Nyquil, and Tylenol PM I am looking for way to normalize my seratonin levels and achieve a good night's sleep naturally.

I have been taking the following:

5-HTP: 200mg
GABA: 1000mg
Valerian Root: 600mg
Melantonin: 3mg
Kava-kava: 50mg
L-Theanine: 100mg
Glycine: 100mg
B6: 50mg
Taurine: 400mg

It has been over 6 months that I had taken Ambien, and I have to admit that is one powerful and addicting drug not to be taken lightly. The above mentioned "stack" does not even come close to the sound-sleep that Ambien provided me. A year ago it would have probably knocked me out taking these supps, now it just sometimes helps.
 
I know exactly what you are saying bro. Ambien is very addictive in that I must take it to go to sleep at night. I have tried not to take it but I just could not ever go into a deep restful sleep without it. The great thing about Ambien is that you can have all the problems in the world but once you pop
it 30 minutes later every worry disappears from your mind.
 
AMbien used to knock me on my ass but now I can take it and still not sleep. I never took it mire than 3-4 days in a row. Tylenol PM is a totally different story. That shit floors me.
 
Guy from work I know got addicted to this stuff. He would experiment with it, like take it and then try to stay up, to fight the sleep, and well now he cant sleep witout it. He claims that Melatonin has helped him alot. The stuff knocks me out, nothing compared to Ambien, but ove only taken ambien a handfull of times.
 
Since when does ambien knochk you out? Maybe I am one of a kind, however if I pop an ambien and do not actually lay down and attempt to sleep, I stay up all night. It doesn't knowck me out in any way. It does however make me trip if I stay up. its also extremely addicting. I was addicted because I was dumb and took it for over 2 years, and it was terrible trying to get off it.
 
  The great thing about Ambien is that you can have all the problems in the world but once you pop it 30 minutes later every worry disappears from your mind

That is the problem with the drug. I would stay up late doing work and then look at the clock thinking I need some sleep. Within 10-15 of popping a pill I was sound asleep and wake up 6 hours later feeling great.

After using it for awhile, I started noticing my mental focus during the day started to diminish. The withdrawal from it was horrible, but I know that drug probably creates some neurological malfunctions and I didn't want to mess with my mind anymore.

I would be interested in anyone who has come clean with the drug sleep aids and what you have used now. It worries me that Ambien permanently affected my ability for a restful sleep now.

Anyone who is using it, I would highly recommend to stop using it.

Here is a little article I pulled:

'Benzo receptors' are actually receptors for the neurotransmitter GABA (gamma amino-butyric acid), which is primarily an inhibitory neurotransmitter (meaning that, when it binds to its receptor, it causes hyperpolarization, and the neuron is less likely to fire an action potential). Benzodiazepines and similar substances (like Ambien) act by binding to a place on the GABA receptor different from where GABA itself binds, but when benzos are present, a little GABA goes a longer way -- neurons affected are even LESS likely to depolarize and fire an action potential. This is what makes Benzos and Ambien useful as hypnotics.

After repeated use of benzos, neurons do adapt in a variety of ways. One of them may be downregulation of receptor synthesis -- so FEWER GABA receptors. This is an attempt at synapse homeostasis. The neuron is trying to keep things in balance. It senses too much GABA-ish activity and compensates by giving GABA and benzos fewer things to bind to. So long term benzo (or Ambien) users may have fewer GABA receptors.

The thing is, as benzo use is reduced or eliminated, the neurons again try to keep things in balance -- eventually upregulating receptor synthesis so that there are an appropriate # of GABA receptors to balance the amount of GABA activity.

So the bottom line is, DON'T WORRY about 'brain damage'. Brains are remarkably plastic. They can change this way, and they can change that way. Most prescription sleep drugs can cause rebound effects because of this plasticity. But also because of this plasticity, the rebound doesn't last forever.
 
Ugh:
1) it's GABA-ergic activity you should be worried about due to Ambien (benzodiazepine) nature of activity
2) your stack while might seem like a remedy, you are essentilly attempting to mimic ambiens effects - induce same GABA-ergic activity via those substances, and while due to their weaker action your receptors might resenthysize, I would strongly suggest finding a GABA-antagonist or NMDA-agonist to restore natural GABA activity.

And, Ambien, is plain nasty; have you tried Trazodone? Maybe Clonazepam - a benzodiazepine but with longer half-life=less side-effects!
 
And, Ambien, is plain nasty; have you tried Trazodone? Maybe Clonazepam - a benzodiazepine but with longer half-life=less side-effects!
Trazodone is very effiective for sleeping.It's a short acting SRI at higher doses ie.150mgs and up.It also has antagonistic binding properties for the 5HT2 serotonin receptor.This is the one that is activated with most SSRI's and can cause activation/agitation,insomnia and libido problems in most users.It also demonstrates slight alpha2 antagonism which can cause priapism in some users.
It is beneficial for sleep because 2 half-lives have cleared during a 8 hour sleep.The half-life is 4hrs for the period from 3-10hrs after dosing and 7-8hrs for the period from 10-34hrs.

A benzo with a longer half-life does not=less sides.Clonazepam which has a half-life of 18-50 hrs and diazepam(valium)>50hrs are in the system longer and can make one feel lethargic and cognitively compromised for some time as aposed to benzo's like alprazolam,oxazepam which have half-lives of approx.8hrs.Taken before sleep,the drugs concentration and activity would be greatly reduced during day-time activities.Sleeping meds like zopiclone(imovane)zolpidem(ambien)and zaleplon(starnoc) are gaba agonists with short half-lives ie.approx. 2hrs.
What I think Juve meant was that short-acting benzo's are harder to discontinue due to the withdrawl demonstrated with shorter acting agents.This is why it is standard protocol to switch to an eqivalent dose of diazepam for tapering purposes ie.0.5mgs alprazolam=10mgs of diazepam.Then you would reduce the dosage of diazepam by 5mgs every week or two until discontiuation is achieved.This allows for slow gradual decreases in benzo concentration and gradual increases of your own natural GABA production.

Cheers...B32
 
Oh dude, youre asking to get into a world of trouble. Sports and Body Building in general has pain associated with it. You start taking drugs like that to "HELP" you cope with that pain, and you are stirring up a recipe for self destruction.


You must spread some Karma around before giving it to b1ewsw32 again.

wesley90 said:
What about pain killers such as Percocet and Vicodin? Do they inhibit muscle gain at all?
 
slash747 said:
Oh dude, youre asking to get into a world of trouble. Sports and Body Building in general has pain associated with it. You start taking drugs like that to "HELP" you cope with that pain, and you are stirring up a recipe for self destruction.

You must spread some Karma around before giving it to b1ewsw32 again.
Same here...I'll hit you up asap...Thanks for the attempt.

B32
 
juve said:
And, Ambien, is plain nasty; have you tried Trazodone? Maybe Clonazepam - a benzodiazepine but with longer half-life=less side-effects!

Sorry, no more drugs for sleeping. Trazodone is not a very "nice" drug from what I have read either. I believe some forms of it is used as tranquilizers to "put down" wild animals. It is also used to treat schizo/bipolar disorders. Treating one drug's withdrawals with another drug is simply not a good idea.

Stay away from the Benzos!

Here is a nice read on what to expect:

http://www.benzo.org.uk/riklist.htm
 
wesley90 said:
What about pain killers such as Percocet and Vicodin? Do they inhibit muscle gain at all?

Bad idea.

Mu opiod receptor agonists inhibit the release of gonadotropin releasing hormone and corticotropin releasing factor which in turn decreases plasma levels of luteinizing hormone, follicle stimulating hormone, ACTH and Beta endorphins. In addition, although there is an increase in growth hormone, this occurs concurrently with an increase in prolactin and inantidiuretic hormone.

Jenetic
 
b1ewsw32 said:
What I think Juve meant was that short-acting benzo's are harder to discontinue due to the withdrawl demonstrated with shorter acting agents.This is why it is standard protocol to switch to an eqivalent dose of diazepam for tapering purposes ie.0.5mgs alprazolam=10mgs of diazepam.Then you would reduce the dosage of diazepam by 5mgs every week or two until discontiuation is achieved.This allows for slow gradual decreases in benzo concentration and gradual increases of your own natural GABA production.


:dolphin: :)
 
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