The biggest thing that causes fear for me and should be the main concern for all is prostate enlargement and prostate cancer wich is the number one cause of death in men.They actually do a castrating type of surgery to stop your body from producing androgens to stop further agravation of the prostate if they are able to control the cancer.I read in mens health that androgens and testosterone are one of the main culprits for prostate cancer,and thats not even artificial their talking about thats just what we naturally produce.Imagine what putting 10 times the amount we produce for long periods of times in your body is doing to the prostate,I dont know why I never see anyone ever mention this as an issue when speaking of sides but it is by far the worst and one of the ones that can be deadly and comon.