Please Scroll Down to See Forums Below Hey guys. I have a question about r-ALA and how much to take daily. I see that the Anabolic Fitness Store has pure r-ALA in 100mg capsules/100 count for about 19 bucks. The problem is, that if I am supposed to take 3000 Mg per day - thats going to get REAL expensive REAL fast. Since it is r-ALA, is 3000 MG per day optimal, or is a smaller dose better for r-ALA? Also, if 3000mg per day IS optimal, how the heck do you guys afford it?!?! BTW - stats - 6' 2", 200 LBS.
r-ALA questions
- Thread starter newpump
- Start date
macrophage69alpha
New member
while an exacting comparison (or even a truely accurate generalization) is not yet available due to lack of use among the "athletic and non-diabetic population"...
HOWEVER... you can assume that dosage will be LESS than 50% of the amount of racemic ALA... it VERY likely as low as a third.. perhaps even less.
ONe of the main factors in determining effectiveness is going to be the increase in insulin (a negative effect) that S-ala causes as well as the extent to which it directly interferes with R-ala binding and reduction to Dihydrolipoic acid (though this secondary concern is more related to its anti-oxident effects.. particularly with respect to use to counter DNP effects.. as well as its anti-aging potential)
HOWEVER... you can assume that dosage will be LESS than 50% of the amount of racemic ALA... it VERY likely as low as a third.. perhaps even less.
ONe of the main factors in determining effectiveness is going to be the increase in insulin (a negative effect) that S-ala causes as well as the extent to which it directly interferes with R-ala binding and reduction to Dihydrolipoic acid (though this secondary concern is more related to its anti-oxident effects.. particularly with respect to use to counter DNP effects.. as well as its anti-aging potential)
. I prolly will be purchasing today - just curious, what dose do you recommend I start with? BTW - Yohimburn has been fantastic as well. Really good stuff.macrophage69alpha
New member
between 600-1200mg..spread throughout the day... if just using to increase post workout uptake 100-300mg with post workout meal/drink..
(600mg is the dosage most commonly used with diabetics.. and the 1200mg.. which may be actually a little high.. should be AT LEAST equivilent to 3g of the racemic ALA).. lean toward starting with the 600.. and PERHAPS... slowly moving up.. to see the difference FOR YOU..
(600mg is the dosage most commonly used with diabetics.. and the 1200mg.. which may be actually a little high.. should be AT LEAST equivilent to 3g of the racemic ALA).. lean toward starting with the 600.. and PERHAPS... slowly moving up.. to see the difference FOR YOU..
macrophage69alpha
New member
duey said:
really cant say for sure.. but the dosage will be similar to racemic mixture.. as reduction to DHLA (the "active", in this respect.. metabolite) is similar in this tissue (though in the brain, kidney and heart reduction of s-ala about 1/7 to 1/8 of r-ala and yet may block its reduction in these tissues)
the research is pretty limited.. as most of the r-ala and s-ala comparative studies are with respect to glucose tolerance and uptake effects... though the one study did find that conversion of s-ala was cytosolic which may affect activity.. will look into it more fully
..
riskybizz007
New member
bought 2 bottles as well... hope it's worth the extra cash
macrophage69alpha
New member
riskybizz007 said:
time will tell.. though the indications of the studies are that the difference is considerable.. likely 3 fold with respect to glucose uptake, disposal and insulin sensitization.. in some aspects estimated to be 7 fold (particularly retinal protection.. ie DNP users) the only area where it MIGHT not be superior is in liver protection (but not clear as S-ala is is reduced to DHLA in the cytosol as opposed to mitchrodria)
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