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PyroGenX (my new fat burner)...

  • Thread starter Thread starter Anthony Roberts
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Anthony Roberts

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I'm going to tell you guys a bit about the new Fat Burner I'm coming out with.

It's called "PyroGenX" and is part of the "Anthony Roberts" line of supplements produced by Protein Factory. If you've got any questions for me, I'd love to answer them in this thread. Omega, Nelson, Primordial, BRR, and Triceptor (Carl Lanore) have all known about this product for months now, and I've sent them all the literature, because I respect and value their opinions. All of them were blown away by the study I sent (the full version of the abstract below). It's just a damn impressive product, and when my friends and colleagues tell me that they think it's good, then I know it will be. Also...remember, this is unheard of in the supplement industry...sending a copy of your research for your next product to people who own their own supplement businesses. But I wanted good advice, so I turned to good people.

Anyway...

It primarily works by Mitochondrial Uncoupling, via UCP1 (though there is UCP2 & UCP3 action as well). Think of it like a nutritional version of dnp - dinitrophenol - , which comes from naturally occuring sources. The primary ingredient is Fucoxanthin*. I've also added some other stuff I think is good, but you're probably only interested in the Fucoxanthin.

The dose I'm putting in PyroGenX is 500mgs/cap. And they're going to be bad ass liquid-caps, so they get totally absorbed, 100%. Anyway, in the study I have (thirty fucking bucks to buy the thing!), it shows that in the test animals, a 2% fucoxanthin rich diet (1-2 caps with each meal will get you there), the animals in the test group ended up with 15% less bodyweight and a 25% reduction in abdominal fat.

So I thought this would be a great product, contacted Protein Factory, and it's in production right now. Should be available by the end of this week or next.

Anyway, here's the abstract of the study which shows Fucoxanthin to do what I was just talking about:

Fucoxanthin from edible seaweed, Undaria pinnatifida, shows antiobesity effect through UCP1 expression in white adipose tissues.
Maeda H, Hosokawa M, Sashima T, Funayama K, Miyashita K.

Laboratory of Biofunctional Material Chemistry, Division of Marine Bioscience, Graduate School of Fisheries Sciences, Hokkaido University, Hakodate, Hokkaido 041-8611, Japan.

Mitochondrial uncoupling protein 1 (UCP1) is usually expressed only in brown adipose tissue (BAT) and a key molecule for metabolic thermogenesis to avoid an excess of fat accumulation. However, there is little BAT in adult humans. Therefore, UCP1 expression in tissues other than BAT is expected to reduce abdominal fat. Here, we show reduction of abdominal white adipose tissue (WAT) weights in rats and mice by feeding lipids from edible seaweed, Undaria pinnatifida. Clear signals of UCP1 protein and mRNA were detected in WAT of mice fed the Undaria lipids, although there is little expression of UCP1 in WAT of mice fed control diet. The Undaria lipids mainly consisted of glycolipids and seaweed carotenoid, fucoxanthin. In the fucoxanthin-fed mice, WAT weight significantly decreased and UCP1 was clearly expressed in the WAT, while there was no difference in WAT weight and little expression of UCP1 in the glycolipids-fed mice. This result indicates that fucoxanthin upregulates the expression of UCP1 in WAT, which may contribute to reducing WAT weight.

PMID: 15896707 [PubMed - indexed for MEDLINE]
 
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Nice! I was trying to find info on PyroGenX weeks ago and couldn't. I will absolutely check out protein factory and give it a run.

Are we saying that calories don't need to be cut or cut as low for effect? Also, would any similar sides associated with DNP be expected?

Anthony Roberts said:
I'm going to tell you guys a bit about the new Fat Burner I'm coming out with.

It's called "PyroGenX" and is part of the "Anthony Roberts" line of supplements produced by Protein Factory. If you've got any questions for me, I'd love to answer them in this thread. Omega, Primordial, BRR, and Triceptor have all known about this product for months now, and I've sent them all the literature, because I respect and value their opinions. All of them were blown away by the study I sent (the full version of the abstract below). It's just a damn impressive product, and when my friends and colleagues tell me that they think it's good, then I know it will be. Anyway...

It primarily works by Mitochondrial Uncoupling, via UCP1 (though there is UCP2 & UCP3 action as well). Think of it like a nutritional version of dnp - dinitrophenol - , which comes from naturally occuring sources. The primary ingredient is Fucoxanthin*. I've also added some other stuff I think is good, but you're probably only interested in the Fucoxanthin.

The dose I'm putting in PyroGenX is 500mgs/cap. And they're going to be bad ass liquid-caps, so they get totally absorbed, 100%. Anyway, in the study I have (thirty fucking bucks to buy the thing!), it shows that in the test animals, a 2% fucoxanthin rich diet (1-2 caps with each meal will get you there), the animals in the test group ended up with 15% less bodyweight and a 25% reduction in abdominal fat.

So I thought this would be a great product, contacted Protein Factory, and it's in production right now. Should be available by the end of this week or next.

Anyway, here's the abstract of the study which shows Fucoxanthin to do what I was just talking about:

Fucoxanthin from edible seaweed, Undaria pinnatifida, shows antiobesity effect through UCP1 expression in white adipose tissues.
Maeda H, Hosokawa M, Sashima T, Funayama K, Miyashita K.

Laboratory of Biofunctional Material Chemistry, Division of Marine Bioscience, Graduate School of Fisheries Sciences, Hokkaido University, Hakodate, Hokkaido 041-8611, Japan.

Mitochondrial uncoupling protein 1 (UCP1) is usually expressed only in brown adipose tissue (BAT) and a key molecule for metabolic thermogenesis to avoid an excess of fat accumulation. However, there is little BAT in adult humans. Therefore, UCP1 expression in tissues other than BAT is expected to reduce abdominal fat. Here, we show reduction of abdominal white adipose tissue (WAT) weights in rats and mice by feeding lipids from edible seaweed, Undaria pinnatifida. Clear signals of UCP1 protein and mRNA were detected in WAT of mice fed the Undaria lipids, although there is little expression of UCP1 in WAT of mice fed control diet. The Undaria lipids mainly consisted of glycolipids and seaweed carotenoid, fucoxanthin. In the fucoxanthin-fed mice, WAT weight significantly decreased and UCP1 was clearly expressed in the WAT, while there was no difference in WAT weight and little expression of UCP1 in the glycolipids-fed mice. This result indicates that fucoxanthin upregulates the expression of UCP1 in WAT, which may contribute to reducing WAT weight.

PMID: 15896707 [PubMed - indexed for MEDLINE]
 
You don't have to cut calories and you'll still lose weight. Just make sure you are taking enough PyroGenX to compensate for having calories at maintenance.
 
This is really interesting stuff. I've felt for sometime that non CNS fat burners are the wave of the future. This looks like the first major leap in that direction. We may soon say bye, bye to stims.
 
Nelson Montana said:
This is really interesting stuff. I've felt for sometime that non central nervous system fat burners are the wave of the future. This looks like the first major leap in that direction. We may soon say bye, bye to stims.

Yeah...the problem with the CNS stuff is that after a few weeks, you can still get your money's worth at an all you can eat buffet, even after you take ECA or whatever.

I'm really, really happy with this product, and really excited about seeing it out there on the market. And then retiring from designing supps!
 
interesting, I'd like to see how humans respond to it, have you run any trials with people yet? got any testers who are trying it?
 
ironclaw said:
interesting, I'd like to see how humans respond to it, have you run any trials with people yet? got any testers who are trying it?


I'd like to know the same? And if ya need a human tester I've got my hand waaaayyyyy up! lol!
 
Had Anthony not ran with this idea I would have included the fucoxanthin in Primordial's next fat burning product. It should workout to be good stuff…

-Pp
 
Anthony Roberts said:
I'm going to tell you guys a bit about the new Fat Burner I'm coming out with.

It's called "PyroGenX" and is part of the "Anthony Roberts" line of supplements produced by Protein Factory. If you've got any questions for me, I'd love to answer them in this thread. Omega, Nelson, Primordial, BRR, and Triceptor (Carl Lanore) have all known about this product for months now, and I've sent them all the literature, because I respect and value their opinions. All of them were blown away by the study I sent (the full version of the abstract below). It's just a damn impressive product, and when my friends and colleagues tell me that they think it's good, then I know it will be. Also...remember, this is unheard of in the supplement industry...sending a copy of your research for your next product to people who own their own supplement businesses. But I wanted good advice, so I turned to good people.

Anyway...

It primarily works by Mitochondrial Uncoupling, via UCP1 (though there is UCP2 & UCP3 action as well). Think of it like a nutritional version of dnp - dinitrophenol - - dinitrophenol - , which comes from naturally occuring sources. The primary ingredient is Fucoxanthin*. I've also added some other stuff I think is good, but you're probably only interested in the Fucoxanthin.

The dose I'm putting in PyroGenX is 500mgs/cap. And they're going to be bad ass liquid-caps, so they get totally absorbed, 100%. Anyway, in the study I have (thirty fucking bucks to buy the thing!), it shows that in the test animals, a 2% fucoxanthin rich diet (1-2 caps with each meal will get you there), the animals in the test group ended up with 15% less bodyweight and a 25% reduction in abdominal fat.

So I thought this would be a great product, contacted Protein Factory, and it's in production right now. Should be available by the end of this week or next.

Anyway, here's the abstract of the study which shows Fucoxanthin to do what I was just talking about:

Fucoxanthin from edible seaweed, Undaria pinnatifida, shows antiobesity effect through UCP1 expression in white adipose tissues.
Maeda H, Hosokawa M, Sashima T, Funayama K, Miyashita K.

Laboratory of Biofunctional Material Chemistry, Division of Marine Bioscience, Graduate School of Fisheries Sciences, Hokkaido University, Hakodate, Hokkaido 041-8611, Japan.

Mitochondrial uncoupling protein 1 (UCP1) is usually expressed only in brown adipose tissue (BAT) and a key molecule for metabolic thermogenesis to avoid an excess of fat accumulation. However, there is little BAT in adult humans. Therefore, UCP1 expression in tissues other than BAT is expected to reduce abdominal fat. Here, we show reduction of abdominal white adipose tissue (WAT) weights in rats and mice by feeding lipids from edible seaweed, Undaria pinnatifida. Clear signals of UCP1 protein and mRNA were detected in WAT of mice fed the Undaria lipids, although there is little expression of UCP1 in WAT of mice fed control diet. The Undaria lipids mainly consisted of glycolipids and seaweed carotenoid, fucoxanthin. In the fucoxanthin-fed mice, WAT weight significantly decreased and UCP1 was clearly expressed in the WAT, while there was no difference in WAT weight and little expression of UCP1 in the glycolipids-fed mice. This result indicates that fucoxanthin upregulates the expression of UCP1 in WAT, which may contribute to reducing WAT weight.

PMID: 15896707 [PubMed - indexed for MEDLINE]

interesting....what about safety any long term studies about side effects on humans?
 
Primordial Performance said:
Had Anthony not ran with this idea I would have included the fucoxanthin in Primordial's next fat burning product. It should workout to be good stuff…

-Pp

That's when I knew I had a winner. When people in the industry would use it themselves in their next product if I hadn't.
 
slimsc said:
Hey AR...

when will the caps be available for consumption... :)

A week or two. Also..there's 2 other bad ass ingredients in this stuff...just like my other products, 3 ingredients each...
 
Anthony Roberts said:
A week or two. Also..there's 2 other bad ass ingredients in this stuff...just like my other products, 3 ingredients each...


hey pro,

looks good... i am really wanting to give it a try...
 
Magick69 said:
interesting....what about safety any long term studies about side effects on humans?

interesting....what about safety any long term studies about side effects on humans?
 
The Second Ingredient In Pyrogenx!

The second ingredient in PyroGenX is Korean Pine Nut (Pinolenic Acid). At first, I resisted putting in an appetite suppressant, but then I thought that really, if you're not putting a strong stimulant into a fat burner, then you probably need some kind of appetite suppression with a Mitochondrial Uncoupler. This is because, frankly, based on my experience with them, you feel like garbage when you eat too much...sweaty, tired, hot, and miserable. SO I decided to put in Pinolenic Acid into the mix. It's a polyunsaturated fatty acid which is actually pretty healthy for you because it lowers blood pressure as well as improves cholesterol (1-2).

It Pinolenic Acid curbs your appetite by stimulating the release of the cholecystokinin (CCK) and Glucagon-Like Peptide (GLP-1), which is are hormones that tells your brain it's time to stop eating(3)...it boosts those hormones by 25% and 60%, RESPECTIVELY, FOR 4 HOURS (4)many other appetite suppressants work by antagonizing ghrelin, which will also tell your brain that you're full, but will potentially halt the release of GH as well. Pinolenic Acid has tha advantage of being very good for your blood lipids (and we know that cutting cycles often involve harsh compounds like Winny, halo, etc..)...so this should really be a home run. It's healthy and will help suppress appetite...

Although 3g of this stuff was used in the paper which examined this property of Korean Pine Nut, I didn't put that much in. Why not? Honestly, it's just too much. I don't think that that kind of dose is necessary, nor that kind of appetite suppression. Not with the Fucoxanthin already in the PyroGenX. Plus, remember...you'll likely be taking 6-12 caps a day, and that'll get you up to a level of Pinolenic acid that will provide a nice clean appetite suppression without killing your appetite completely, and making you look like you went on the Paris Hiltom diet...

Anyway, that's ingredient #2 in the PyroGenX. I'll let you know what the third (and final) ingredient is shortly.

References:

1. Sugano M, Ikeda I, Wakamatsu K, Oka T. Influence of Korean pine (Pinus koraiensis)seed oil containing cis-5,cis-9,cis-l2-octadecatrienoic acid on polyunsaturated fatty acid metabolism, eicosanoid production and blood pressure of rats. Br J Nutr. 1994 Nov;72(5):775-83.
2.. Lee JW, Lee KW, Lee SW, Kim IH, Rhee C. Selective increase in pinolenic acid (all-cis5,9,12-18:3) in Korean pine nut oil by crystallization and its effect on LDL-receptor activity. Lipids. 2004 Apr;39(4):383-7.
3. Causey JL. Korean pine nut fatty acids induce satiety-producing hormone release in overweight human volunteers. Paper presented at: American Chemical Society National Meeting & Exposition; March 26-30, 2006; Atlanta, GA. AGFD 117.
4. *Paper presentation: “Korean pine nut fatty acids affect appetite sensations, plasma CCK and GLP1 in overweight subjects,” 12:30 p.m.-3 p.m. Monday April 3, Physiology Obesity and Satiety 494.2/board #C781.
 
It's too bad you didn't get bloodwork with the Myo. I wonder if you didn't get results or you didn't "feel" results.
 
There was a poll on steroid.com where about a quarter of the people who responded said they didn't "feel" anything on 600mgs/week of Eq.

I always wonder about people "feeling" results...

Also...as an FYI, about as many people felt that MyoGenX helped them (at least a little) as felt that EQ worked for them. So I mean...a lot of times you have to look at things like that.
 
Faizakafez said:
What about a free sample i know one person using cyogenx for a prep...

i wont give it bb.com review ;)

Who's using Cyo for prep???
 
a female friend of mine, its not a big deal

but i can use Pyro for my prep and log it with unbiased results...

also how is it for energy?
 
When did you get a female friend??!?

Pyro is not good for energy at all. It's got a small amount of caffeine in it, but that's mostly for it's properties on UCP2 & 3, and to deal with the lethargy of having a mitochondrial uncoupler as potent as Fucoxanthin in it. You won't feel tired on Pyro, but it's got no energy producing properties that are going to be noteworthy.

Amp02 or Lipoflame is much better for energy.

As for samples...I don't handle that, unfortunately. BRR may be giving out samples here on EF, though...it's not my dept. If he does, I'll get your name put in there.

P.S. - I hate logs, personally.
 
lol....its not R.C , there are bbuilders in canada fyi.


good thing you addressed the energy issue most people assume with fatburners yeild energy focus ..


but i personally dont like blogs ;) but i check them out from time to time...
 
How is it working for your friend? I know that it seems to get awesome results in women...far better than I would have imagined possible...they're getting a lot leaner on it, and their mood is well improved...
 
Cha’ de bugre is the final ingredient I’m putting in PyroGenX. It comes from the Cordia salicifolia tree (Paraguay.). I’ve decided to include it because a mitochondrial uncoupler can make you a bit lethargic. See, this stuff has been used for hundreds of years in Paraguay as a mild stimulant (contains potassium, allantoin, allantonic acid, and caffeine), but the reason I really like it is because it contains Potassium as well, and it’s easy to become low in potassium on an Uncoupler. Also, remember….caffeine has mild UCP2 & UCP3 expression…so you get all 3 uncoupling proteins being expressed with PyroGenX.

I put 100mgs of the CDB in each cap, because I think that’s going to be enough to keep you stimulated and not suffering from the Uncoupling effects…but not enough that you can use the pill as an actual stimulant…it’s likely that the mild stimulant effects from the CDB will just be enough so you don’t feel lethargic from the Fucoxanthin. And, of course, if you care to look it up, the CDB has some good folk-type uses for fat loss and such on it’s own in the country it’s from.

So there you have it…the three ingredients in PyroGenX:

Fucoxanthin
Pinolenic Acid
Cha’ de Burgre
 
No idea. Pfizer is being contracted into making the liquid caps...I don't want the caps to be a regular powder, so it's all on them now.
 
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